| Company Name: |
TCI Europe |
| Tel: |
320-37350700 |
| Email: |
sales@tcieurope.eu |
| Company Name: |
TCI AMERICA |
| Tel: |
800-4238616 |
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sales@tciamerica.com |
Biotin-PEG6-Mal manufacturers
- Biotin-PEG6-amido-Mal
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2025-06-07
- CAS:1808990-66-0
- Min. Order: 100mg
- Purity: >98.00%
- Supply Ability: 100mg
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| | Biotin-PEG6-Mal Basic information |
| Product Name: | Biotin-PEG6-Mal | | Synonyms: | Biotin-PEG6-Mal;(+)-Biotin-PEG6-Maleimide;(+)-Biotin-PEG6-NH-Mal;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[24-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-22-oxo-3,6,9,12,15,18-hexaoxa-21-azatetracos-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-;N-[2-[2-[2-[2-[2-[2-[2-[(3-Maleimidopropionyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]biotinamide;N-Biotinyl-N'-(3-maleimidopropionyl)-3,6,9,12,15,18-hexaoxaicosane-1,20-diamine;Biotin-PEG6-amido-Mal;Biotin-PEG6-CH2CH2-NH-Mal | | CAS: | 1808990-66-0 | | MF: | C31H51N5O11S | | MW: | 701.83 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1808990-66-0.mol |  |
| | Biotin-PEG6-Mal Chemical Properties |
| Boiling point | 944.7±65.0 °C(Predicted) | | density | 1.229±0.06 g/cm3(Predicted) | | solubility | Soluble in DCM | | form | powder to crystal | | pka | 13.90±0.40(Predicted) | | color | White to Light yellow |
| | Biotin-PEG6-Mal Usage And Synthesis |
| Description | Biotin-PEG6-Mal is a maleimide biotinylation linker that can react with sulfhydryl groups (at pH 6.5-7.5) specifically to form a thioether linkage. The hydrophilic PEG spacer increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. | | Uses | Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329 |
| | Biotin-PEG6-Mal Preparation Products And Raw materials |
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