- DL-Valinol
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- $15.00
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2021-07-02
- CAS:16369-05-4
- Min. Order: 1KG
- Purity: 99%+ HPLC
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| | DL-2-Amino-3-methyl-1-butanol Basic information |
| Product Name: | DL-2-Amino-3-methyl-1-butanol | | Synonyms: | DL-VALINOL;2-Amino-3-methylbutan-1-ol 95+%;rac-(R*)-2-Amino-3-methylbutane-1-ol;rac-(R*)-3-Methyl-2-amino-1-butanol;DL-2-Amino-3-methyl-1-butanol,95%;[1-(Hydroxymethyl)-2-methylpropyl]amine;N-(1-Hydroxy-3-methylbutan-2-yl)amine;rac-Valinol | | CAS: | 16369-05-4 | | MF: | C5H13NO | | MW: | 103.16 | | EINECS: | 240-425-0 | | Product Categories: | | | Mol File: | 16369-05-4.mol |  |
| | DL-2-Amino-3-methyl-1-butanol Chemical Properties |
| Melting point | 31-32℃ | | Boiling point | 75-77 °C8 mm Hg(lit.) | | density | 0.936 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.4543(lit.) | | Fp | 194 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | Water Solubility | Soluble in water | | form | Liquid | | pka | 12.82±0.10(Predicted) | | color | Clear yellow | | Optical Rotation | 0.3825°(C=1g/100ml ETOH) | | InChI | InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3 | | InChIKey | NWYYWIJOWOLJNR-UHFFFAOYSA-N | | SMILES | C(O)C(N)C(C)C | | CAS DataBase Reference | 16369-05-4(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37 | | RIDADR | 2735 | | WGK Germany | 3 | | HS Code | 29221990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | DL-2-Amino-3-methyl-1-butanol Usage And Synthesis |
| Chemical Properties | CLEAR YELLOW LIQUID | | Uses | 2-Amino-3-methyl-1-butanol was used in the synthesis of 1-allyl-2-pyrroleimines. It was also used as chiral nucleophile in the total synthesis of benanomicin-pradimicin antibiotics. It was used as homochiral guest compound during synthesis of crown ethers containing two chiral subunits. | | Definition | ChEBI: 2-Amino-3-methyl-1-butanol is an amino alcohol. | | Synthesis | Example 2: To a dry 12 liter glass reaction vessel (with equipment as described in Example 1) was added 900 grams (7.7 moles) of DL-valine and 2.5 liters of tetrahydrofuran. 1.05 liters (8.5 moles) of boron trifluoride diethyl ether compound and 0.85 liters (8.5 moles) of borane-dimethyl sulfide complex were added sequentially according to the method of Example 1, followed by refluxing. The addition process lasted for 8 hours and heating was continued for 3 hours after the addition was completed. The reaction mixture was quenched with 0.75 liters of tetrahydrofuran/water mixture and subsequently hydrolyzed with 24.6 moles of aqueous sodium hydroxide. The product was separated according to the method described in Example 1, resulting in 494 g (62% yield) of 2-amino-3-methyl-1-butanol having a boiling point of 78°-79°C (8 mm), refractive index n20D 1.4543, and a purity of 97% by gas chromatography (glc) analysis. | | References | [1] Patent: US3935280, 1976, A |
| | DL-2-Amino-3-methyl-1-butanol Preparation Products And Raw materials |
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