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3-Amino-4-pyridinol

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3-Amino-4-pyridinol manufacturers

  • 3-Aminopyridin-4-ol
  • 3-Aminopyridin-4-ol pictures
  • $1.10
  • 2026-08-20
  • CAS:6320-39-4
  • Min. Order: 1g
  • Purity: 99.00%
  • Supply Ability: 100 Tons Min
3-Amino-4-pyridinol Basic information
Product Name:3-Amino-4-pyridinol
Synonyms:4-HYDROXY-3-AMINO PYRIDINE;3-AMINO-PYRIDIN-4-OL;3-AMINO-4-HYDROXYPYRIDINE 4-HYDROXY-3-AMINO PYRIDINE;4-Hydroxy-3-Amino;3-AMINO-4-HYDROXYPYRIDINE, HPLC 99%;3-Amino-4-hydroxypyridine hydrate, 95%;3-amino-1H-pyridin-4-one;3-amino-4-pyridone
CAS:6320-39-4
MF:C5H6N2O
MW:110.11
EINECS:676-800-4
Product Categories:aminopyridin;Heterocycle-Pyridine series;pharmacetical;Amines;Pyridines;Pyridine
Mol File:6320-39-4.mol
3-Amino-4-pyridinol Structure
3-Amino-4-pyridinol Chemical Properties
Melting point 145-149°C
Boiling point 508.9±35.0 °C(Predicted)
density 1.320±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
form powder to crystal
pka5.04±0.18(Predicted)
color Light yellow to Brown
InChIInChI=1S/C5H6N2O/c6-4-3-7-2-1-5(4)8/h1-3H,6H2,(H,7,8)
InChIKeyOIIBRAGQGFLUFI-UHFFFAOYSA-N
SMILESC1=NC=CC(O)=C1N
CAS DataBase Reference6320-39-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-40-41-37/38-22
Safety Statements 22-26-36-39-37
HazardClass IRRITANT
HS Code 29333999
MSDS Information
3-Amino-4-pyridinol Usage And Synthesis
Uses3-Amino-4-hydroxypyridine is a useful synthesis reagent.
Synthesis
4-Hydroxy-3-nitropyridine

5435-54-1

3-Amino-4-pyridinol

6320-39-4

4-Hydroxy-3-nitropyridine (2.8 g, 20.0 mmol) was dissolved in 150 mL of methanol and 280 mg of Pd/C catalyst was added. The air in the reaction flask was replaced with hydrogen, which was continuously vented, and the reaction was carried out at room temperature, and the progress of the reaction was monitored by thin-layer chromatography (TLC) until the completion of the reaction. The reaction mixture was filtrated, the filter cake was washed with methanol, the filtrates were combined and concentrated under reduced pressure to give 3-amino-4-hydroxypyridine as a black to orange oily liquid (1.98 g, 90% yield).

References[1] Patent: US2007/105891, 2007, A1. Location in patent: Page/Page column 10
[2] Patent: US2011/28467, 2011, A1. Location in patent: Page/Page column 15
[3] Patent: CN108373476, 2018, A. Location in patent: Paragraph 0390-0394
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 24, p. 9742 - 9753
[5] Roczniki Chemii, 1955, vol. 29, p. 119,127
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