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| | 2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE Basic information |
| Product Name: | 2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE | | Synonyms: | 5-nitro-3-trifluoromethyl-2-hydroxypyridine;2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE;5-NITRO-3-(TRIFLUOROMETHYL-2-PYRIDONE);2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine 98%;2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine98%;5-Nitro-3-(trifluoromethyl)pyridin-2-ol, 5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one;5-Nitro-3-(trifluoromethyl)pyridin-2-one;5-aMino-3-(trifluoroMethyl)pyridin-2(1H)-one | | CAS: | 99368-66-8 | | MF: | C6H3F3N2O3 | | MW: | 208.09 | | EINECS: | 848-721-7 | | Product Categories: | Fluorine series;Pyridines;Pyridine | | Mol File: | 99368-66-8.mol |  |
| | 2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE Chemical Properties |
| Melting point | 158°C | | Boiling point | 255.2±40.0 °C(Predicted) | | density | 1.61±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | form | solid | | pka | 5.71±0.10(Predicted) | | color | Yellow | | InChI | InChI=1S/C6H3F3N2O3/c7-6(8,9)4-1-3(11(13)14)2-10-5(4)12/h1-2H,(H,10,12) | | InChIKey | BHUILUYFGJBXHQ-UHFFFAOYSA-N | | SMILES | C1(=O)NC=C([N+]([O-])=O)C=C1C(F)(F)F | | LogP | 0.41 at 25℃ | | CAS DataBase Reference | 99368-66-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | Hazard Note | Irritant | | HS Code | 2933399990 |
| | 2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE Usage And Synthesis |
| Chemical Properties | 2-Hydroxy-5-nitro-3-trifluoromethylpyridine is solid at room temperature and pressure, and it is a pyridine derivative. The hydroxyl group in the 2nd position in the structure and the double bond on the pyridine ring form the enol form that will be reciprocally isomorphic into the structure of amide. | | Uses | 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine is a class of aromatic heterocyclic compounds that can be used as intermediates for Apalutamide, which is an androgen receptor inhibitor used in the treatment of prostate cancer. |
| | 2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE Preparation Products And Raw materials |
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