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4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine

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4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine manufacturers

  • Fmoc-D-Aph(Cbm)-OH
  • Fmoc-D-Aph(Cbm)-OH pictures
  • $150.00
  • 2023-06-26
  • CAS:324017-22-3
  • Min. Order: 10g
  • Purity: more than 99.6%
  • Supply Ability: 500kg/month
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Basic information
Product Name:4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine
Synonyms:4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine;(9H-Fluoren-9-yl)MethOxy]Carbonyl D-Aph(Cbm)-OH;Fmoc-D-4-Aph(cbm);(2R)-3-[4-(carbamoylamino)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid;D-Phenylalanine, 4-[(aminocarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-;4-[(Aminocarbonyl)amino]-N-Fmoc-D-phenylalanine;Fmoc-D-Aph(Cbm);Fmoc-D-Phe(4-[(NH2CO)NH2])-OH
CAS:324017-22-3
MF:C25H23N3O5
MW:445.47
EINECS:
Product Categories:
Mol File:324017-22-3.mol
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Structure
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Chemical Properties
Melting point 163℃ (decomposition)
Boiling point 699.1±55.0 °C(Predicted)
density 1.376±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka3.82±0.10(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic
InChIKeyHFPDOFBZCSQAEJ-JOCHJYFZSA-N
SMILESC(O)(=O)[C@@H](CC1=CC=C(NC(N)=O)C=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
Safety Information
MSDS Information
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Usage And Synthesis
UsesFmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity[1].
References[1] Guangcheng Jiang, et al. "GnRH antagonists: a new generation of long acting analogues incorporating p-ureido-phenylalanines at positions 5 and 6." Journal of medicinal chemistry 44.3 (2001): 453-467. DOI:10.1021/jm0003900
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Preparation Products And Raw materials
Tag:4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine(324017-22-3) Related Product Information
Fmoc-Lys(Boc)(isopropyl)-OH Fmoc-D-Cit-OH FMoc-D-4-Aph(tBu-CbM)-OH Fmoc-3-(2-Naphthyl)-D-alanine Fmoc-N-Me-Tyr(tBu)-OH FMOC-D-alanine (9H-Fluoren-9-yl)MethOxy]Carbonyl HomoArg(Et)2-OH·HCl (symmetrical) FMOC-D-4-Chlorophe Fmoc-Lys(nicotinoyl)-OH (R)-N-Acetyl-2-naphthylalanine Fmoc-D-Asn(Trt)-OH Fmoc-D-homoArg(Et)2-OH·HCl Fmoc-Lys(Pal-Glu-OtBu)-OH (R)-N-Fmoc-(3-Pyridyl)alanine N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine