TYRPHOSTIN A1 manufacturers
- Tyrphostin A1
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- $30.00
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2026-08-08
- CAS:2826-26-8
- Purity: 98.32%
- Supply Ability: 10g
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| | TYRPHOSTIN A1 Basic information |
| Product Name: | TYRPHOSTIN A1 | | Synonyms: | (4-METHOXYBENZYLIDENE)MALONITRILE;(4-METHOXYBENZYLIDENE)MALONONITRILE;((4-METHOXYPHENYL)METHYLENE)METHANE-1,1-DICARBONITRILE;2-[(4-METHOXYPHENYL)METHYLENE]MALONONITRILE;2-(4-METHOXYBENZYLIDENE)-MALONONITRILE;RARECHEM AL BX 0083;TYRPHOSTIN AG 9;TYRPHOSTIN A1 | | CAS: | 2826-26-8 | | MF: | C11H8N2O | | MW: | 184.19 | | EINECS: | | | Product Categories: | | | Mol File: | 2826-26-8.mol |  |
| | TYRPHOSTIN A1 Chemical Properties |
| Melting point | 113-116 °C(lit.) | | Boiling point | 352.4±27.0 °C(Predicted) | | density | 1.169±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | chloroform: soluble50mg/mL, clear, light yellow | | form | Yellow solid | | color | Light orange to Yellow to Green | | λmax | 350nm(H2O)(lit.) | | Sensitive | Light Sensitive | | InChI | 1S/C11H8N2O/c1-14-11-4-2-9(3-5-11)6-10(7-12)8-13/h2-6H,1H3 | | InChIKey | UOHFCPXBKJPCAD-UHFFFAOYSA-N | | SMILES | COc1ccc(cc1)\C=C(/C#N)C#N |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | Safety Statements | 36/37 | | RIDADR | UN 3439 6.1/PG III | | WGK Germany | 3 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29269095 | | Storage Class | 11 - Combustible Solids |
| | TYRPHOSTIN A1 Usage And Synthesis |
| Chemical Properties | light yellow crystalline needles or crystals | | Uses | Tyrphostin A1 is an inactive Tyrphostin used as a negative control for Tyrphostin A23. | | Definition | ChEBI: Tyrphostin 1 is a member of methoxybenzenes. It has a role as a geroprotector. | | Synthesis Reference(s) | Synthetic Communications, 21, p. 1163, 1991 DOI: 10.1080/00397919108021035
Synthesis, p. 23, 1970 | | Biological Activity | Tyrphostin 1 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain. Tyrphostin 1 is also known to block EGF-dependent receptor autophosphorylation,. Furthermore, studies have reported th at tyrphostin 1 can block Ca2+ channels and inhibit growth in vascular smooth muscle cells,.', 'EGFR tyrosine kinase inhibitor. |
| | TYRPHOSTIN A1 Preparation Products And Raw materials |
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