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| | ethylene dimethanesulfonate Basic information |
| Product Name: | ethylene dimethanesulfonate | | Synonyms: | Ethylene bis(me;2-methylsulfonyloxyethyl methanesulfonate;Ethylene glycol dimesylate;ethylene dimethanesulfonate;ETHANEDIMETHANESULFONATE;ETHYLENEDIMETHANESULPHONATE;ETHYLENEGLYCOL,DIMETHANESULPHONATE;ETHYLENEDIMESYLATE | | CAS: | 4672-49-5 | | MF: | C4H10O6S2 | | MW: | 218.25 | | EINECS: | | | Product Categories: | | | Mol File: | 4672-49-5.mol |  |
| | ethylene dimethanesulfonate Chemical Properties |
| Melting point | 35-36 °C | | Boiling point | 328.93°C (rough estimate) | | density | 1.400 (estimate) | | refractive index | 1.5630 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Sparingly, Heated), Methanol (Very Slightly) | | form | Solid | | color | White to Off-White |
| | ethylene dimethanesulfonate Usage And Synthesis |
| Uses | Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs[1]. | | Biological Activity | Ethylene dimethanesulfonate is a mild alkylated ethylene glycol nonvolatile methanesulfonate diester. It has a selective pro-apoptotic effect on LC. | | in vivo | Ethylene dimethanesulfonate (subcutaneous injection; 75 mg/kg; 7 days) disrupts epididymal function and leads to sperm granuloma formation in rat. | | References | [1] Dutta D, et al. Ethylene dimethane sulfonate (EDS) ablation of Leydig cells in adult rat depletes testosterone resulting in epididymal sperm granuloma: Testosterone replacement prevents granuloma formation. Reprod Biol. 2019 Mar;19(1):89-99. DOI:10.1016/j.repbio.2018.11.005 |
| | ethylene dimethanesulfonate Preparation Products And Raw materials |
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