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| | Lipoamido-PEG3-Azide Basic information |
| Product Name: | Lipoamido-PEG3-Azide | | Synonyms: | Lipoamido-PEG3-Azide;LA-PEG3-N3;LIPOAMIDO-PEG3-N3;Lipoamido-PEG4-azide;N-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl)-5-(1,2-dithiolan-3-yl)pentanamide | | CAS: | 890016-39-4 | | MF: | C16H30N4O4S2 | | MW: | 406.5638 | | EINECS: | | | Product Categories: | peg | | Mol File: | 890016-39-4.mol |  |
| | Lipoamido-PEG3-Azide Chemical Properties |
| solubility | Soluble in DMSO, DMF, DCM |
| | Lipoamido-PEG3-Azide Usage And Synthesis |
| Description | Lipoamido-PEG3-azide is a PEG linker comprised of a lipoamide group and a terminal azide group. The azide group can participate in copper-catalyzed Click Chemistry reactions with alkynes, DCBO and BCN reagents to form triazole moieties. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | | Uses | Lipoamido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] H. Tetsuo Uyeda, et al. Synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots. doi: 10.1117/12.590494 |
| | Lipoamido-PEG3-Azide Preparation Products And Raw materials |
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