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| | DBCO-NH-(CH2)4COOH Basic information |
| | DBCO-NH-(CH2)4COOH Chemical Properties |
| Boiling point | 770.9±60.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | pka | 4.70±0.10(Predicted) |
| | DBCO-NH-(CH2)4COOH Usage And Synthesis |
| Uses | DBCO-NH-(CH2)4COOH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NH-(CH2)4COOH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | Alkyl-Chain | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | DBCO-NH-(CH2)4COOH Preparation Products And Raw materials |
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Tag:DBCO-NH-(CH2)4COOH(2375193-74-9)
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