- Scabertopin
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- $81.00 / 1mg
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2026-01-16
- CAS:185213-52-9
- Min. Order:
- Purity: 99.13%
- Supply Ability: 10g
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| | Scabertopin Basic information |
| Product Name: | Scabertopin | | Synonyms: | Scabertopin;Gpr52 antagonist E7
(Scabertopin);2-Butenoic acid, 2-methyl-, (3aR,4S,9S,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-methylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester, (2Z)-;Scabertopin, 10 mM in DMSO | | CAS: | 185213-52-9 | | MF: | C20H22O6 | | MW: | 358.39 | | EINECS: | | | Product Categories: | | | Mol File: | 185213-52-9.mol |  |
| | Scabertopin Chemical Properties |
| Boiling point | 592.7±50.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | form | Solid | | color | White to light yellow | | InChI | InChI=1S/C20H22O6/c1-5-11(3)18(21)25-16-9-13-8-14(24-20(13)23)6-10(2)7-15-17(16)12(4)19(22)26-15/h5,7-8,14-17H,4,6,9H2,1-3H3/b10-7+,11-5-/t14-,15+,16-,17-/m0/s1 | | InChIKey | FTPHYXGWMIZVMP-RZYABJHASA-N | | SMILES | C(O[C@H]1CC2=C[C@]([H])(CC(C)=C[C@@]3([H])OC(=O)C(=C)[C@@]31[H])OC2=O)(=O)/C(/C)=C\C |t:10| |
| | Scabertopin Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Elephantopus scaber. | | Uses | Scabertopin is a sesquiterpene lactone. Scabertopin has been found to be prominent anticancer constituents[1][2]. | | Health effects | Didancao species lactone has anti-tumor effect: Didancao has inhibitory effect on the proliferation of various tumor cells. | | Biological Activity | Scabertopin, isolated from Elephantopus scaber, is a sesquiterpene lactone. It is an important anticancer ingredient. | | References | [1] Liang QL, et al. [Structure modification on sesquiterpene lactones from Elephantopus scaber]. Yao Xue Xue Bao. 2007 Nov;42(11):1159-61. PMID:18300472
[2] Hiradeve SM, et al. A review on pharmacology and toxicology of Elephantopus scaber Linn. Nat Prod Res. 2014;28(11):819-30. DOI:10.1080/14786419.2014.883394 |
| | Scabertopin Preparation Products And Raw materials |
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