- 4-Chloro-7-azaindole
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- $0.00 / 1G
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2025-06-11
- CAS:55052-28-3
- Min. Order: 1G
- Purity: 98%min
- Supply Ability: 30kg/month
- 4-Chloro-7-azaindole
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- $0.00 / 25KG
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2025-06-09
- CAS:55052-28-3
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 10000KGS
- 4-Chloro-7-azaindole
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- $0.00 / 1kg
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2025-06-03
- CAS:55052-28-3
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: ton
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| 4-Chloro-7-azaindole Basic information |
| 4-Chloro-7-azaindole Chemical Properties |
Melting point | 176-181 °C | density | 1.425±0.06 g/cm3(Predicted) | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | solubility | Chloroform (Slightly), Methanol (Slightly) | form | solid | pka | 12.98±0.40(Predicted) | color | Light yellow to brown | Water Solubility | Slightly soluble in water. | InChI | InChI=1S/C7H5ClN2/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H,9,10) | InChIKey | HNTZVGMWXCFCTA-UHFFFAOYSA-N | SMILES | C12NC=CC1=C(Cl)C=CN=2 | CAS DataBase Reference | 55052-28-3(CAS DataBase Reference) |
Hazard Codes | Xi,Xn | Risk Statements | 22-37/38-41 | Safety Statements | 26-39 | RIDADR | UN 2811 6.1/PG 3 | WGK Germany | 3 | HazardClass | 6.1 | HazardClass | IRRITANT | PackingGroup | Ⅲ | HS Code | 29339900 |
| 4-Chloro-7-azaindole Usage And Synthesis |
Description | 4-Chloro-7-azaindole belongs to the class of azaindole compounds, which has anticancer, antibacterial, antiviral and other biological activities. 4-Chloro-7-azaindole is mainly used as an organic intermediate in the preparation of 7-azaindole derivatives, GDC-0575, and Janus kinase inhibitors. | Chemical Properties | White to brown solid | Uses | 4-Chloro-7-azaindole can be used as a useful intermediate for drug discovery research. | Uses | A useful intermediate for drug discovery research such as used in the synthesis of 7-azaindole derivatives, synthetic cytokinin analogues. | Preparation | Using 7-azaindole as the raw material, hydrogen peroxide was used to carry out N-oxidation reaction to generate N-oxide. In the reaction between POCl? and N-oxide, diisopropylethylamine (DIPEA) was added as a catalyst to increase the yield. After the reaction was completed, 4-Chloro-7-azaindole was obtained by alkalization treatment with a yield of up to 85.6%. | Synthesis Reference(s) | The Journal of Organic Chemistry, 71, p. 4021, 2006 DOI: 10.1021/jo0602571 |
| 4-Chloro-7-azaindole Preparation Products And Raw materials |
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