Ac-Leu-Glu-Thr-Asp-AFC manufacturers
- Ac-LETD-AFC
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- $56.00
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2026-05-11
- CAS:210345-02-1
- Purity: 99.67%
- Supply Ability: 10g
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| | Ac-Leu-Glu-Thr-Asp-AFC Basic information |
| Product Name: | Ac-Leu-Glu-Thr-Asp-AFC | | Synonyms: | AC-LEU-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-LETD-AFC;N-ACETYL-LEU-GLU-THR-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine;L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI);L-α-Asparagine,N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-;4-[(2-acetamido-4-methylpentanoyl)amino]-5-[[1-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoicacid;N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine, CAS 210345-02-1 | | CAS: | 210345-02-1 | | MF: | C31H38F3N5O12 | | MW: | 729.66 | | EINECS: | | | Product Categories: | | | Mol File: | 210345-02-1.mol |  |
| | Ac-Leu-Glu-Thr-Asp-AFC Chemical Properties |
| Boiling point | 1113.769±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.437±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | −20°C | | solubility | DMSO: 10 mg/ml | | form | White to off-white powder. | | pka | 4.087±0.10(predicted) | | Appearance | Solid Powder |
| | Ac-Leu-Glu-Thr-Asp-AFC Usage And Synthesis |
| Description | Ac-LETD-AFC is a fluorogenic substrate for caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. | | Uses | N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine is a caspase substrate that is cleaved by caspase-8. | | Excitation / Emission Maximum | 400 nm/505 nm | | Sequene | Ac-Leu-Glu-Thr-Asp-Unk |
| | Ac-Leu-Glu-Thr-Asp-AFC Preparation Products And Raw materials |
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