1-isothiocyanato-PEG3-Azide

1-isothiocyanato-PEG3-Azide Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:1-Isothiocyanato-PEG3-azide CAS:1310686-23-7 Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Nextpeptide Inc
Tel:	+86-0571-81612335 +8613336028439
Email:	sales@nextpeptide.com
Products Intro:	Product Name:1-isothiocyanato-PEG3-Azide CAS:1310686-23-7 Purity:98% Min. Package:5KG;1KG

Company Name:	Jilin Chinese Academy of Sciences-yanshen Technology
Tel:	+undefined18143011203
Email:	info@chemextension.com
Products Intro:	Product Name:1-isothiocyanato-PEG3-Azide CAS:1310686-23-7 Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing

Company Name:	Xian confluore Biological Technology Co., Ltd.
Tel:	+86-15680926068
Email:	1924344760@confluore.cn
Products Intro:	Product Name:1-Isothiocyanato-PEG3-azide CAS:1310686-23-7 Purity:>98.00% Package:500mg

Company Name:	Aladdin Scientific
Tel:
Email:	tp@aladdinsci.com
Products Intro:	Product Name:1-isothiocyanato-PEG3-Azide CAS:1310686-23-7 Purity:98% Package:$871.9/100mg;$1441.9/250mg;$2071.9/500mg;$3451.9/1g;Bulk package Remarks:98%

1-isothiocyanato-PEG3-Azide manufacturers

1-isothiocyanato-PEG3-Azide Basic information

Product Name:	1-isothiocyanato-PEG3-Azide
Synonyms:	1-isothiocyanato-PEG3-Azide;1-Isothiocyanato PEG3-alcohol;NCS-peg3-azide
CAS:	1310686-23-7
MF:	C9H16N4O3S
MW:	260.31
EINECS:
Product Categories:
Mol File:	1310686-23-7.mol

1-isothiocyanato-PEG3-Azide Chemical Properties

Safety Information

MSDS Information

1-isothiocyanato-PEG3-Azide Usage And Synthesis

Uses	1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 1-Isothiocyanato-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Biological Activity	1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50	PEGs
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

1-isothiocyanato-PEG3-Azide Preparation Products And Raw materials

Raw materials

Tag:1-isothiocyanato-PEG3-Azide(1310686-23-7) Related Product Information

Azido-PEG3-Maleimide Aminooxy-PEG2-azide Bromo-PEG3-azide Bromoacetamido-PEG4-azido Azido-PEG5-acid MPEG8-N3 - Aminoxy-PEG3-azide Aminooxy-PEG4-azide PEG-Azide, O-(2-Azidoethyl)-Oμ-methylpolyethylene glycol Azido-PEG7-acid Bromo-PEG4-Azide N3-PEG8-CH2CH2COOH 1-isothiocyanato-PEG4-Alcohol

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