A-3 hydrochloride manufacturers
- A3
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-
2026-07-24
- CAS:
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle , 10g/bottle, 100g/bottle
- A-3 hydrochloride
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- $51.00
-
2026-07-15
- CAS:78957-85-4
- Purity: 99.79%
- Supply Ability: 10g
- A-3 hydrochloride
-
- $51.00
-
2026-07-15
- CAS:78957-85-4
- Purity: 99.79%
- Supply Ability: 10g
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| | A-3 hydrochloride Basic information |
| Product Name: | A-3 hydrochloride | | Synonyms: | A-3;TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;1-Naphthalenesulfonamide,N-(2-aminoethyl)-5-chloro-, hydrochloride (1:1);Calmodulin-dependent kinases,CaMK,inhibit,Casein Kinase,PKC,inhibitor,PKA,A 3 hydrochloride,cAMP,calmodulin,kinase,A-3,MLC-kinase,Calmodulin-dependent protein kinases,Protein kinase C,Protein kinase A,A 3,casein,A3 hydrochloride | | CAS: | 78957-85-4 | | MF: | C12H14Cl2N2O2S | | MW: | 321.22 | | EINECS: | | | Product Categories: | Protein Kinase Inhibitors and Activators;Protein Kinase | | Mol File: | 78957-85-4.mol |  |
| | A-3 hydrochloride Chemical Properties |
| Melting point | 173-176°C | | storage temp. | -20°C | | solubility | DMSO: 24 mg/mL | | form | solid | | color | white | | InChI | 1S/C12H13ClN2O2S.ClH/c13-11-5-1-4-10-9(11)3-2-6-12(10)18(16,17)15-8-7-14;/h1-6,15H,7-8,14H2;1H | | InChIKey | VWAGIWCLJAQLAL-UHFFFAOYSA-N | | SMILES | Cl[H].NCCNS(=O)(=O)c1cccc2c(Cl)cccc12 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2935909099 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | A-3 hydrochloride Usage And Synthesis |
| Chemical Properties | White Crystalline Solid | | Uses | Inhibits cAMP and cGMP dependent protein kinases. Also inhibits MLC kinase and protein kinase C | | Biochem/physiol Actions | Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM). | | IC 50 | CK1: 80 μM (Ki); CK2: 5.1 μM (Ki); PKC: 47 μM (Ki); PKA: 4.3 μM (Ki) |
| | A-3 hydrochloride Preparation Products And Raw materials |
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