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| | Cytidine 5'-diphosphate trisodium salt Basic information |
| | Cytidine 5'-diphosphate trisodium salt Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | form | Crystalline Powder | | color | White | | biological source | yeast | | Water Solubility | Freely soluble in water, insoluble in ethanol, chloroform and ether. | | InChI | 1S/C9H15N3O11P2.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18);; | | InChIKey | MAGSIBHRUIBONY-UHFFFAOYSA-N | | SMILES | [Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(=O)OP(O)(O)=O)C(O)C2O |
| | Cytidine 5'-diphosphate trisodium salt Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Uses | Cytidine 5'-Diphosphate trisodium salt (5'-CDPNa3) is a diphosphate nucleoside derived from Cytidine. An inhibitor of glycogenin-catalyzed glucosyl and xylosyl transfer It is used as a therapeutic agent in treatment prevention of myocardial isc hemia accompanied with cerebral ischemia. | | Application | Cytidine 5′-diphosphate sodium salt (5'-CDPNa3) has been used:
- as a substrate in nucleoside diphosphatase (NDPase) enzyme histochemistry assay of gold fish eye sections
- in ribonucleotide reductase assay
- dCDP formation assay.
| | General Description | Cytidine 5′-diphosphate (CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK). CTP synthetase catalyzes the conversion of CTP to CDP intermediates like CDP-diacylglycerol, CDP-choline and CDP-ethanolamine for phospholipid biosynthesis. | | Biochem/physiol Actions | Cytidine 5′-diphosphate (CDP) is used as a substrate of nucleoside diphosphatase kinase to produce CTP for supporting DNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP. | | in vivo | CDP-ribitol can be used for the Diagnostics and research of CDP-l-ribitol pyrophosphorylase A (CRPPA) muscular dystrophy[3]. |
| | Cytidine 5'-diphosphate trisodium salt Preparation Products And Raw materials |
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