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| | 2,5-Diamino-4,6-dihydroxy-pyrimidine Basic information |
| Product Name: | 2,5-Diamino-4,6-dihydroxy-pyrimidine | | Synonyms: | 2,5-DIAMINO-4,6-DIHYDROXYPYRIMIDINE HYDROCHLORIDE HYDRATE;2,5-DIAMINO-4,6-DIHYDROXYPYRIMIDINE;AKOS 91522;2,5-Diamino-4,6-dihydroxypyrimidine HCl monohydrate;2,5-DIAMINOPYRIMIDINE-4,6-DIOL;2,5-Diamino-4,6-dihydroxy pyrimidine HCI. (DADHP HCl);2,5-Diamino-4,6-pyrimidinediol;2,5-Diamino-6-hydroxypyrimidine-4(3H)-one | | CAS: | 40769-69-5 | | MF: | C4H6N4O2 | | MW: | 142.12 | | EINECS: | | | Product Categories: | APIs & Intermediate;Pyrimidine;Starting Raw Materials & Intermediates | | Mol File: | 40769-69-5.mol |  |
| | 2,5-Diamino-4,6-dihydroxy-pyrimidine Chemical Properties |
| Melting point | 260 C | | density | 2.15±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 8.52±0.10(Predicted) | | CAS DataBase Reference | 40769-69-5(CAS DataBase Reference) |
| | 2,5-Diamino-4,6-dihydroxy-pyrimidine Usage And Synthesis |
| Synthesis | Diethyl malonate (32 g, 0.2 mol), guanidine hydrochloride (9.6 g, 0.1 mol), sodium ethanolate (27.2 g, 0.4 mol), ethanol 150 mL was heated and refluxed, and the solid obtained after the reaction and sodium nitrite (13.8 g, 0.2 mol) were reacted in the presence of a solution of 200 mL of water, 170 mL of ethanol, and 16 mL of acetic acid for 24 hr at 25 C. The solid obtained after the reaction was reacted at reflux for 8 hours in the presence of sodium dithionite (43.5 g, 0.25 mol) and water 200 mL to obtain 2,5-diamino-4,6-dihydroxypyrimidine in 48% yield. |
| | 2,5-Diamino-4,6-dihydroxy-pyrimidine Preparation Products And Raw materials |
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