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| | N6-Isopentenyladenosine-d6 Basic information |
| | N6-Isopentenyladenosine-d6 Chemical Properties |
| Melting point | 142-143 °C(Solv: ethanol (64-17-5)) | | Boiling point | 647.2±65.0 °C(Predicted) | | density | 1.56±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | | form | Solid | | pka | 13.12±0.70(Predicted) | | color | White to Light Beige |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | AU7404910 | | HS Code | 29400090 |
| | N6-Isopentenyladenosine-d6 Usage And Synthesis |
| Description | N6-(Δ2-Isopentenyl)adenosine is a precursor in the biosynthesis of the plant hormone N6-(Δ2-isopentenyl)adenine . N6-(Δ2-isopentenyl)adenine may be converted to the cytokinin trans-zeatin by cytochrome P450 mono-oxygenases. Cytokinins, including N6-(Δ2-isopentenyl)adenine and trans-zeatin, regulate diverse events in plant growth and development. N6-(Δ2-Isopentenyl)adenosine can also alter post-transcriptional processes in mammalian cells, altering proliferation and apoptosis. | | Chemical Properties | White to off-white crystalline powder | | Uses | [2H6] N6-Isopentenyladenosine-D6 can be used as analyte in analytical study for acetylation of cytokinins and modified adenine compounds for gas chromatography-mass spectrometric analysis. | | Uses | N6-Isopentenyladenosine has antiproliferative activity on MCF-7 breast cancer cells. | | Definition | ChEBI: A nucleoside analogue in which adenosine has been modified by substitution at the 6-amino nitrogen by a Delta2-isopentenyl group. | | References | [1] NAOYA HIROSE. Regulation of cytokinin biosynthesis, compartmentalization and translocation.[J]. Journal of Experimental Botany, 2008: 75-83. DOI: 10.1093/jxb/erm157
[2] MAURIZIO BIFULCO. Biological and pharmacological roles of N6-isopentenyladenosine: an emerging anticancer drug.[J]. Anti-cancer agents in medicinal chemistry, 2008, 8 2: 200-204. DOI: 10.2174/187152008783497028
[3] SILVANA CASATI. Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells.[J]. Anticancer research, 2011, 31 10: 3401-3406.
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| | N6-Isopentenyladenosine-d6 Preparation Products And Raw materials |
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