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| | α-Bromo-2,3,4,5,6-pentafluorotoluene Basic information |
| Product Name: | α-Bromo-2,3,4,5,6-pentafluorotoluene | | Synonyms: | 1-(Bromomethyl)-2,3,4,5,6-pentafluorobenzene;1-Bromomethylpentafluorobenzene;PFBBR;PENTAFLUOROBENZYL BROMIDE;PENTAFLUOROBROMOMETHYL BENZENE;(BROMOMETHYL)PENTAFLUOROBENZENE;Toluene, alpha-bromo-2,3,4,5,6-pentafluoro-;1-(Bromomethyl)-2,3,4,5,6-pentafluorobenzene, alpha-Bromo-2,3,4,5,6-pentafluorotoluene | | CAS: | 1765-40-8 | | MF: | C7H2BrF5 | | MW: | 260.99 | | EINECS: | 217-182-4 | | Product Categories: | Alkylation Reagent;organofluorine compounds;Aromatic Halides (substituted);Analytical Chemistry;Boronic Acid, etc. (GC Derivatizing Reagents);GC Derivatizing Reagents | | Mol File: | 1765-40-8.mol |  |
| | α-Bromo-2,3,4,5,6-pentafluorotoluene Chemical Properties |
| Melting point | 19-20 °C(lit.) | | Boiling point | 174-175 °C(lit.) | | density | 1.728 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.471(lit.) | | Fp | 181 °F | | storage temp. | Store below +30°C. | | solubility | Chloroform (Soluble), Ethyl Acetate (Slightly), Methanol (Slightly) | | form | Liquid | | Specific Gravity | 1.728 | | color | Clear colorless to yellow | | Water Solubility | Hydrolyzes in water. | | Sensitive | Lachrymatory | | BRN | 647808 | | CAS DataBase Reference | 1765-40-8(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, (bromomethyl)pentafluoro-(1765-40-8) |
| | α-Bromo-2,3,4,5,6-pentafluorotoluene Usage And Synthesis |
| Chemical Properties | CLEAR COLOURLESS TO YELLOWISH LIQUID | | Uses | Pentafluorobenzyl bromide (PFB-Br) is an alkylating reagent which can be used to modify hydroxyl groups, carboxyl groups, sulfhydryl groups, and amines.PFB-Br can also be used to measure nitrite and peroxynitrite.It is a versatile reagent. | | Uses | 2,3,4,5,6-Pentafluorobenzyl bromide is used as a reagent for derivatization of alcohols, carboxylic acids, sulfonamides for GC and polyfunctional thiols. It is used for the preparation of pentafluorobenzyl esters of organic acids for determination by capillary and GC. It is also used to derivatize N-7-substituted guanine adducts of DNA for determination by GC-electron capture-MS. | | Uses | Learn more in the Product Information | | Definition | ChEBI: Pentafluorobenzyl bromide is a member of the class benzyl bromides that is benzyl bromide in which the hydrogens at positions 2, 3, 4, 5 and 6 of the phenyl ring are replaced by fluoro groups. It is a versatile derivatization agent in chromatography and mass spectrometry. It is a member of benzyl bromides and a member of fluorobenzenes. | | General Description | Pentafluorobenzyl bromide (PFB-Br) is a derivatization reagent. Excess reagent may be removed by reaction with an aminophenol. It is an alkylation reagent suitable for electron capture detector (ECD) detection. It is also a lachrymator. | | reaction suitability | reagent type: derivatization reagent
reaction type: Alkylations
reagent type: derivatization reagent
reaction type: Esterifications |
| | α-Bromo-2,3,4,5,6-pentafluorotoluene Preparation Products And Raw materials |
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