| Identification | Back Directory | [Name]
Boc-Aminooxy-PEG3-amine | [CAS]
1235514-18-7 | [Synonyms]
CAS_1235514-18-7
Boc-Aminooxy-PEG3-amine
Boc-Aminooxy-PEG3-C2-NH2
t-Boc-Aminoxy-PEG3-amine
t-Boc-Aminooxy-PEG3-amine
3,6,9,12-Tetraoxa-2-azatetradecanoic acid, 14-amino-, 1,1-dimethylethyl ester | [Molecular Formula]
C13H28N2O6 | [MDL Number]
MFCD24471202 | [MOL File]
1235514-18-7.mol | [Molecular Weight]
308.37 |
| Hazard Information | Back Directory | [Description]
t-Boc-Aminooxy-PEG3-amine is a Boc-protected aminooxy molecule. The amine (NH2) group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc-aminooxy can be deprotected under mild acidic conditions and then reacts with an aldehyde to form a linkage. | [Uses]
Boc-Aminooxy-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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Henan Alfachem Co.,Ltd.
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www.chemicalbook.com/supplier/14555231/ |
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