| Identification | Back Directory | [Name]
Aminooxy-PEG3-methane | [CAS]
248275-10-7 | [Synonyms]
m-PEG3-Aminooxy
Aminooxy-PEG3-methane
O-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)hydroxylamine
Hydroxylamine, O-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]- | [Molecular Formula]
C7H17NO4 | [MDL Number]
MFCD26910997 | [MOL File]
248275-10-7.mol | [Molecular Weight]
179.21 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C, protect from light | [form ]
Liquid | [color ]
Colorless to light yellow | [InChI]
InChI=1S/C7H17NO4/c1-9-2-3-10-4-5-11-6-7-12-8/h2-8H2,1H3 | [InChIKey]
UPZRLQLRXOQKOM-UHFFFAOYSA-N | [SMILES]
NOCCOCCOCCOC |
| Hazard Information | Back Directory | [Description]
Aminooxy-PEG3-methane is a aminooxy-containing PEG reagent The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. | [Uses]
m-PEG3-Aminooxy is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Luo W, et al. Tailored electroactive and quantitative ligand density microarrays applied to stem cell differentiation. J Am Chem Soc. 2010 Mar 3;132(8):2614-21. DOI:10.1021/ja907187f |
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