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2-Amino-6-methoxy-3-nitropyridine

2-Amino-6-methoxy-3-nitropyridine structure

CAS No.: 73896-36-3

Chemical Name:: 2-Amino-6-methoxy-3-nitropyridine

Synonyms: 6-METHOXY-3-NITROPYRIDIN-2-AMINE;TENA-001;2-Amino-6-methoxy-3-nitropyrid;6-Methoxy-3-nitropyridin-2-amin;6-Methoxy-3-Nitro-2-Pyridinamine;2-AMINO-6-METHOXY-3-NITROPYRIDINE;2-AMINO-3-NITRO-6-METHOXYLPYRIDINE;2-AMINO-3-NITRO-6-METHOXY PYRIDINE;2-PYRIDINAMINE, 6-METHOXY-3-NITRO-;6-METHOXY-3-NITRO-2-PYRIDINYLAMINE

CBNumber:: CB2462264

Molecular Formula:: C6H7N3O3

Molecular Weight:: 169.14

MDL Number:: MFCD03206481

MOL File:: 73896-36-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-08-28 09:47:25

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2-Amino-6-methoxy-3-nitropyridine Properties

Melting point	171-172°C
Boiling point	338.5±37.0 °C(Predicted)
Density	1.400±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	solid
pka	0.17±0.50(Predicted)
color	Yellow
InChI	1S/C6H7N3O3/c1-12-5-3-2-4(9(10)11)6(7)8-5/h2-3H,1H3,(H2,7,8)
InChIKey	RDJILYVRVOTMTQ-UHFFFAOYSA-N
SMILES	COc1ccc(c(N)n1)[N+]([O-])=O
CAS DataBase Reference	73896-36-3(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H302-H315-H319-H334-H335

Precautionary statements

P301+P312+P330-P302+P352-P305+P351+P338

target organs

Respiratory system

Hazard Codes

Xi,Xn

Risk Statements

22-36/37/38-43

Safety Statements

26-36/37

WGK Germany

HazardClass

IRRITANT

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

2-Amino-6-methoxy-3-nitropyridine price More Price(54)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	704598	2-Amino-6-methoxy-3-nitropyridine 97%	73896-36-3	1g	$33.8	2023-01-07	Buy
Sigma-Aldrich	704598	2-Amino-6-methoxy-3-nitropyridine 97%	73896-36-3	5g	$133	2023-01-07	Buy
TCI Chemical	A2372	2-Amino-6-methoxy-3-nitropyridine >97.0%(GC)	73896-36-3	5g	$112	2026-04-30	Buy
TCI Chemical	A2372	2-Amino-6-methoxy-3-nitropyridine >97.0%(GC)	73896-36-3	25g	$389	2026-04-30	Buy
AstaTech	51956	2-AMINO-3-NITRO-6-METHOXYPYRIDINE 97%	73896-36-3	25G	$53	2026-04-30	Buy

Product number	Packaging	Price	Buy
704598	1g	$33.8	Buy
704598	5g	$133	Buy
A2372	5g	$112	Buy
A2372	25g	$389	Buy
51956	25G	$53	Buy

2-Amino-6-methoxy-3-nitropyridine Chemical Properties, Uses, Production

Chemical Properties

Yellow solid

Uses

2-Amino-6-methoxy-3-nitropyridine is used as an intermediate in the drug tetrapazole.

Synthesis

124-41-4

27048-04-0

73896-36-3

1. 7.78 g (0.144 mol) of sodium methanolate was mixed with 50.0 mL of methanol and the mixture was cooled to 15 °C. 2. 25.0 g (0.144 mol) of 2-amino-6-chloro-3-nitropyridine was slowly added to the above solution while maintaining 15°C. 3. the reaction mixture was heated to 25°-30°C and stirred continuously at this temperature for 4-5 hours. 4. The progress of the reaction was monitored by thin layer chromatography (TLC). 5. Upon completion of the reaction, the reaction mixture was slowly poured into water to precipitate the product. 6. The precipitate was collected by filtration and washed with cold water. 7. After drying, 21.0 g of 2-amino-3-nitro-6-methoxypyridine was obtained in 86.5% yield and 99.0% purity by HPLC. 8. 8. The melting point of the product was 167°-169°C. 9. 9. 1H-NMR (CDCl3) data: δ 3.89 ppm (single peak, 3H, OCH3), 6.14-6.16 ppm (twin peaks, 1H), 8.24-8.27 ppm (twin peaks, 1H), 8.16 ppm (single peak, 2H, -NH2).

References

[1] Patent: US2006/80790, 2006, A1. Location in patent: Page/Page column 3
[2] European Journal of Medicinal Chemistry, 2016, vol. 117, p. 19 - 32
[3] Journal of Medicinal Chemistry, 1997, vol. 40, # 12, p. 1808 - 1819
[4] Patent: WO2014/57415, 2014, A2. Location in patent: Page/Page column 47

2-Amino-6-methoxy-3-nitropyridine synthesis

Synthesis of 2-Amino-6-methoxy-3-nitropyridine from Sodium Methoxide and 2-Amino-6-chloro-3-nitropyridine

2-Amino-6-methoxy-3-nitropyridine Preparation Products And Raw materials

Raw materials

O-methylhydroxylamine 2-Amino-6-methoxypyridine 2-Chloro-6-methoxy-3-nitropyridine 2-Amino-6-chloropyridine 6-Chloropicolinic acid

tert-Butyl (6-Chloropyridin-2-yl)-carbamate Methanol Zinc chloride 2-Methoxy-5-nitropyridine Sodium Methoxide

2,6-Dichloro-3-nitropyridine 2,6-Dichloropyridine

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Preparation Products

2-Amino-6-chloro-3-nitropyridine 5-Iodo-6-Methoxy-3-nitro-pyridin-2-ylaMine

2-Amino-6-methoxy-3-nitropyridine Suppliers

Global Suppliers ( 258)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66
Pure Chemistry Scientific Inc.	62
Accela ChemBio Co.,Ltd.	64
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64

View Latest Price from 2-Amino-6-methoxy-3-nitropyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	2-Amino-6-methoxy-3-nitropyridine 73896-36-3	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2026-05-28	2-Amino-6-methoxy-3-nitropyridine 73896-36-3	$2.00-5.00	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2025-04-04	2-Amino-6-methoxy-3-nitropyridine 73896-36-3		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

2-Amino-6-methoxy-3-nitropyridine
73896-36-3
$1.10
99.00%
Dideu Industries Group Limited

2-Amino-6-methoxy-3-nitropyridine
73896-36-3
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

2-Amino-6-methoxy-3-nitropyridine
73896-36-3
98%
Henan Aochuang Chemical Co.,Ltd.

2-Amino-6-methoxy-3-nitropyridine Spectrum

2-Amino-6-methoxy-3-nitropyridine(73896-36-3)¹HNMR

73896-36-3 (2-Amino-6-methoxy-3-nitropyridine) Related Search:

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Pyridine Nitrogen dioxide 2-Amino-4-methoxy-3-nitropyridine 4-Amino-2-methoxy-3-nitropyridine 2-Aminopyridine

4-Amino-3-methoxy-5-nitropyridine 6-Methoxy-3-nitro-5-phenyl-pyridin-2-ylamine 5-Bromo-6-methoxy-3-nitro-pyridin-2-ylamine

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6-Methoxy-3-nitro-pyridin-2-ylamine 2-Amino-6-methoxy-3-nitropyrid 2-AMINO-3-NITRO-6-METHOXYLPYRIDINE 2-Amino-6-methoxy-3-nitropyridine ,98% TENA-001 6-METHOXY-3-NITRO-2-PYRIDINYLAMINE 2-PYRIDINAMINE, 6-METHOXY-3-NITRO- 2-AMINO-3-NITRO-6-METHOXY PYRIDINE 2-AMINO-6-METHOXY-3-NITROPYRIDINE 6-Methoxy-3-Nitro-2-Pyridinamine 2-Amino-6-methoxy-3-nitropyridine > 2-Amino-6-methoxy-3-nitropyridine ISO 9001：2015 REACH 6-Methoxy-3-nitropyridin-2-amin 2-Amino-3-nitro-6-methoxypyridine, CAS 73896-36-3 6-METHOXY-3-NITROPYRIDIN-2-AMINE 73896-36-3 73869-36-3 C6H7N3O3 Pyridine Pyridine series Amines Pyridines Pyridines derivates