2-Amino-3,5-dichloropyridine
- CAS No.
- 4214-74-8
- Chemical Name:
- 2-Amino-3,5-dichloropyridine
- Synonyms
- 3,5-DICHLOROPYRIDIN-2-AMINE;AKOS BBS-00001349;BUTTPARK 153\57-29;TIMTEC-BB SBB003932;Edoxaban Impurity 104;3,5-dichloro-3-pyridylamine;3,5-DICHLORO-2-PYRIDINAMINE;2-AMINO-3,5-DICHLIROPYRIDINE;3,5-Dichloro-2-AminoPyridine;2-AMINO-3,5-DICHLOROPYRIDINE
- CBNumber:
- CB0356640
- Molecular Formula:
- C5H4Cl2N2
- Molecular Weight:
- 163
- MDL Number:
- MFCD00006313
- MOL File:
- 4214-74-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 81-83 °C(lit.) |
|---|---|
| Boiling point | 268.76°C (rough estimate) |
| Density | 1.5462 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Powder or Crystals |
| pka | 2.43±0.10(Predicted) |
| color | Off-white to pink to beige |
| Water Solubility | insoluble |
| BRN | 119376 |
| InChI | InChI=1S/C5H4Cl2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9) |
| InChIKey | OCWBGKZFOYMCCN-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C(Cl)C=C1Cl |
| CAS DataBase Reference | 4214-74-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H302-H312-H332 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280h-P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-37/39-28A-45-24/25 | |||||||||
| RIDADR | UN2811 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
2-Amino-3,5-dichloropyridine price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A1502 | 2-Amino-3,5-dichloropyridine >98.0%(GC)(T) | 4214-74-8 | 5g | $25 | 2026-04-30 | Buy |
| TCI Chemical | A1502 | 2-Amino-3,5-dichloropyridine >98.0%(GC)(T) | 4214-74-8 | 25g | $77 | 2026-04-30 | Buy |
| Usbiological | 258302 | 2-Amino-3,5-dichloropyridine Asreported | 4214-74-8 | 25g | $337 | 2026-06-03 | Buy |
| Usbiological | 258302 | 2-Amino-3,5-dichloropyridine Asreported | 4214-74-8 | 50g | $460 | 2026-06-03 | Buy |
| Usbiological | 258302 | 2-Amino-3,5-dichloropyridine Asreported | 4214-74-8 | 100g | $613 | 2026-06-03 | Buy |
2-Amino-3,5-dichloropyridine Chemical Properties,Uses,Production
Chemical Properties
LIGHT BEIGE TO GREY CRYSTALLINE POWDER OR FLAKES
Uses
3,5-Dichloropyridin-2-amine can be used as herbicidal active substances.
Synthesis
1072-98-6
4214-74-8
General procedure for the synthesis of 2-amino-3,5-dichloropyridine from 2-amino-5-chloropyridine: 5500 mL of a solvent mixture of DMF and methanol with a volume ratio of 2.5:1 was added to a 10L three-necked round-bottomed flask, a thermometer was mounted and configured with condensation reflux device, and a magnetic stirrer was started. 2560.8 g of 2-amino-5-chloropyridine and 6118.4 g of N-chlorosuccinimide were added sequentially, and the reaction mixture was stirred at 45 °C for 2.5 hours. The reaction progress was monitored by TLC and GC until the reaction was complete. After completion of the reaction, the solvent was removed by distillation to obtain the crude product, which was purified by recrystallization with ethanol to afford the target compound 2-amino-3,5-dichloropyridine. The product was dried in 70.5% yield and 98.20% purity (GC analysis).
References
[1] European Journal of Organic Chemistry, 2012, # 28, p. 5595 - 5604
[2] Patent: CN104016908, 2016, B. Location in patent: Paragraph 0027; 0028
[3] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1928, vol. 60, p. 689
[4] Chem. Zentralbl., 1928, vol. 99, # II, p. 1671
2-Amino-3,5-dichloropyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Yuxiang Chemical Co., Ltd | 13809076511 | 344679571@qq.com | China | 311 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 2-Amino-3,5-dichloropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 3,5-Dichloro-2-pyridinamine
4214-74-8
|
$8.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-07 | 2-Amino-3,5-dichloropyridine
4214-74-8
|
$20.00-100.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-03-20 | 2-Amino-3,5-dichloropyridine
4214-74-8
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 3,5-Dichloro-2-pyridinamine
4214-74-8
- $8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Amino-3,5-dichloropyridine
4214-74-8
- $20.00-100.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Amino-3,5-dichloropyridine
4214-74-8
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
