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METHYL CHLORODIFLUOROACETATE

CAS No.
1514-87-0
Chemical Name:
METHYL CHLORODIFLUOROACETATE
Synonyms
METHYL 2-CHLORO-2,2-DIFLUOROACETATE;CHLORODIFLUOROACETATE;Methyldifluorochlorate;METHYL CHLORODIFLUOROACETATE;Methylchlorodifluoroacetate99%;METHYL DIFLUOROCHLOROACETIC ACID;Methyl chlorodifluoroacetate 99%;Methyl Chlorodifluoroacetate >Methyl5-Chloro-3,4-dibromobenzoate;chlorodifluoro-aceticacimethylester
CBNumber:
CB3310708
Molecular Formula:
C3H3ClF2O2
Molecular Weight:
144.5
MDL Number:
MFCD00000775
MOL File:
1514-87-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:22:39
Product description Number Pack Size Price
Methyl chlorodifluoroacetate 99% 300837 25g $94.5
Methyl chlorodifluoroacetate 99% 300837 5g $31.8
Methyl Chlorodifluoroacetate >97.0%(GC) C1586 5g $24
Methyl Chlorodifluoroacetate >97.0%(GC) C1586 25g $61
Methyl Chlorodifluoroacetate Asreported 284844 10g $309
More product size

METHYL CHLORODIFLUOROACETATE Properties

Boiling point 79-81 °C(lit.)
Density 1.37 g/mL at 25 °C(lit.)
refractive index n20/D 1.349(lit.)
Flash point 67 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
form Liquid
Specific Gravity 1.371
color Clear colorless
Sensitive Moisture Sensitive
BRN 1756072
InChI InChI=1S/C3H3ClF2O2/c1-8-2(7)3(4,5)6/h1H3
InChIKey AWUPLMYXZJKHEG-UHFFFAOYSA-N
SMILES C(OC)(=O)C(Cl)(F)F
CAS DataBase Reference 1514-87-0(CAS DataBase Reference)
EPA Substance Registry System Acetic acid, chlorodifluoro-, methyl ester (1514-87-0)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)
GHS02,GHS05
Signal word  Danger
Hazard statements  H225-H314
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
Hazard Codes  F,C
Risk Statements  11-34-37
Safety Statements  16-26-36/37/39-45
RIDADR  UN 2924 3/PG 2
WGK Germany  3
19
Hazard Note  Highly Flammable/Moisture Sensitive
TSCA  TSCA listed
HazardClass  3
PackingGroup  II
HS Code  29159000
Limited Quantities 1.0 L (0.3 gallon) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
3
3 0

METHYL CHLORODIFLUOROACETATE price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 300837 Methyl chlorodifluoroacetate 99% 1514-87-0 25g $94.5 2026-04-30 Buy
Sigma-Aldrich 300837 Methyl chlorodifluoroacetate 99% 1514-87-0 5g $31.8 2023-06-20 Buy
TCI Chemical C1586 Methyl Chlorodifluoroacetate >97.0%(GC) 1514-87-0 5g $24 2026-04-30 Buy
TCI Chemical C1586 Methyl Chlorodifluoroacetate >97.0%(GC) 1514-87-0 25g $61 2026-04-30 Buy
Usbiological 284844 Methyl Chlorodifluoroacetate Asreported 1514-87-0 10g $309 2026-06-03 Buy
Product number Packaging Price Buy
300837 25g $94.5 Buy
300837 5g $31.8 Buy
C1586 5g $24 Buy
C1586 25g $61 Buy
284844 10g $309 Buy

METHYL CHLORODIFLUOROACETATE Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Methyl chlorodifluoroacetate was used in preparation of 2,2-difluoro-3-hydroxyesters and gem-difluorocyclopropane.

General Description

Methyl chlorodifluoroacetate is a trifluoromethylating agent.

Synthesis

Ethane, 1-chloro-1,1,2,2-tetrafluoro-2-methoxy-

404582-64-5

METHYL CHLORODIFLUOROACETATE

1514-87-0

Methyl 2-chloro-2,2-difluoroacetate (CH3O(CO)CF2Cl) was synthesized using 1-chloro-1,1,2,2-tetrafluoro-2-methoxyethane (CH3OCF2CF2Cl) as a starting material by performing the reaction according to the reaction conditions of Example 3. Upon completion of the reaction, the target product methyl 2-chloro-2,2-difluoroacetate was obtained in 67% (1.34 mmol) yield.

References

[1] Patent: US2006/25639, 2006, A1. Location in patent: Page/Page column 4

354-24-5
1514-87-0
Synthesis of METHYL CHLORODIFLUOROACETATE from CHLORODIFLUOROACETYL CHLORIDE
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View Lastest Price from METHYL CHLORODIFLUOROACETATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHYL CHLORODIFLUOROACETATE pictures 2026-05-05 METHYL CHLORODIFLUOROACETATE
1514-87-0
$80.00-800.00 10kg 0.99 20tons Zibo Hangyu Biotechnology Development Co., Ltd
METHYL CHLORODIFLUOROACETATE pictures 2025-06-27 METHYL CHLORODIFLUOROACETATE
1514-87-0
1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
METHYL CHLORODIFLUOROACETATE pictures 2025-06-20 METHYL CHLORODIFLUOROACETATE
1514-87-0
$3.00-20.00 1KG 0.99 30 tons Hebei Yanxi Chemical Co., Ltd.
Acetic acid, chlorodifluoro-, methyl ester chlorodifluoro-aceticacimethylester CHLORODIFLUOROACETIC ACID METHYL ESTER METHYL DIFLUOROCHLOROACETIC ACID METHYL CHLORODIFLUOROACETATE Methyl chlorodifluoroacetate 99% Methylchlorodifluoroacetate99% 2,2-Difluoro-2-chloroacetic acid methyl ester Methyl5-Chloro-3,4-dibromobenzoate Methyl 2-chloro-2,2-difluoroacetate,99% 2-Chloro-2,2-difluoro-1-methoxyethan-1-one Methy1 2-chloro-2,2-difluoroacetate Methyl chlorodifluoroacetate Acetic acid,2-chloro-2,2-difluoro-, Methyl ester Methyl 2-chloro-2,2-difluoroethanoate, Chloro(difluoro)acetic acid methyl ester Methyl 2-chloro-2,2-difluoroacetate, 99% 25GR Methyl Chlorodifluoroacetate > Acetic acid, 2-chloro-2,2-difluoro-, methyl ester Methyldifluorochlorate CHLORODIFLUOROACETATE METHYL 2-CHLORO-2,2-DIFLUOROACETATE 1514-87-0 C3H3ClF2O2 ClCF2CO2CH3 ClF2CCOOCH3 ClF2O2C3H3 Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Fluorinated Building Blocks Esters Organic Building Blocks C2 to C5 Carbonyl Compounds Building Blocks Fluorinated Building Blocks Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Synthetic Organic Chemistry C2 to C5 Carbonyl Compounds Esters