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BOC-L-2-Fluorophe

BOC-L-2-Fluorophe Structure
BOC-L-2-Fluorophe structure
CAS No.
114873-00-6
Chemical Name:
BOC-L-2-Fluorophe
Synonyms
(S)-2-((tert-Butoxycarbonyl)aMino)-3-(2-fluorophenyl)propanoic acid;BOC-PHE(2-F)-OH;BOC-PHE(O-F)-OH;BOC-L-2-FLUOROPHE;BOC-L-PHE(2-F)-OH;BOC-2-FLUORO-L-PHE;RARECHEM BK PT 0020;BOC-O-FLUORO-PHE-OH;(S)-BOC-2-Fluorophe;Boc-o-fluoro-L-Phe-OH
CBNumber:
CB5745883
Molecular Formula:
C14H18FNO4
Molecular Weight:
283.3
MDL Number:
MFCD00672520
MOL File:
114873-00-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:24:35
Product description Number Pack Size Price
Boc-2-fluoro-L-phenylalanine Asreported 264942 2g $343
Boc-2-fluoro-L-phenylalanine Asreported 264942 5g $569
Boc-2-fluoro-L-phenylalanine Asreported 264942 10g $789
Boc-2-fluoro-L-phenylalanine Asreported 264942 25g $1177
Boc-2-fluoro-L-phenylalanine Asreported 264942 50g $1679
More product size
Request For Quotation

BOC-L-2-Fluorophe Properties

Melting point 92-96 °C
alpha 10 º (c=1,EtOAc)
Boiling point 427.3±40.0 °C(Predicted)
Density 1.1918 (estimate)
storage temp. Sealed in dry,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 3.87±0.11(Predicted)
Appearance White to off-white Solid
optical activity [α]20/D +9±1°, c = 1% in ethyl acetate
BRN 5347990
Major Application peptide synthesis
InChI 1S/C14H18FNO4/c1-14(2,3)20-13(19)16-11(12(17)18)8-9-6-4-5-7-10(9)15/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)/t11-/m0/s1
InChIKey NTWUXBKUDXGMHV-NSHDSACASA-N
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1F)C(O)=O
CAS DataBase Reference 114873-00-6(CAS DataBase Reference)
UNSPSC Code 12352200
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H413
Precautionary statements  P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
Hazard Note  Irritant/Keep Cold
HS Code  2922498590
Storage Class 13 - Non Combustible Solids
NFPA 704
0
0 0

BOC-L-2-Fluorophe price More Price(84)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 264942 Boc-2-fluoro-L-phenylalanine Asreported 114873-00-6 2g $343 2026-06-03 Buy
Usbiological 264942 Boc-2-fluoro-L-phenylalanine Asreported 114873-00-6 5g $569 2026-06-03 Buy
Usbiological 264942 Boc-2-fluoro-L-phenylalanine Asreported 114873-00-6 10g $789 2026-06-03 Buy
Usbiological 264942 Boc-2-fluoro-L-phenylalanine Asreported 114873-00-6 25g $1177 2026-06-03 Buy
Usbiological 264942 Boc-2-fluoro-L-phenylalanine Asreported 114873-00-6 50g $1679 2026-06-03 Buy
Product number Packaging Price Buy
264942 2g $343 Buy
264942 5g $569 Buy
264942 10g $789 Buy
264942 25g $1177 Buy
264942 50g $1679 Buy

BOC-L-2-Fluorophe Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

peptide synthesis

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

2-FLUORO-L-PHENYLALANINE

19883-78-4

BOC-L-2-Fluorophe

114873-00-6

General steps: 1. 2-Fluoro-L-phenylalanine (1.00 g) was dissolved in a mixture of dioxane (10 ml) and water (5 ml) under cooling conditions in an ice bath. 2. 1N aqueous sodium hydroxide solution (5.46 ml) and di-tert-butyl dicarbonate (1.38 ml) were slowly added to the above solution, keeping the reaction system in an ice bath. 3. The ice bath was removed and the reaction mixture was stirred at room temperature for 1 hour. 4. Upon completion of the reaction, the reaction mixture was concentrated under reduced pressure to remove the organic solvent. 5. The pH of the concentrate was adjusted to 2.5 with dilute hydrochloric acid. 6. 6. The aqueous phase was extracted with ethyl acetate (100 ml x 3) and the organic phases were combined. 7. Wash the organic phase with water and saturated saline in turn. 8. 8. Dry the organic phase with anhydrous sodium sulfate and filter to remove the desiccant. 9. The filtrate was concentrated under pressure to obtain the crude product. 10. The crude product was recrystallized with ethyl acetate-petroleum ether mixed solvent to obtain N-Boc-2-fluoro-L-phenylalanine (1.32 g, 85% yield) as colorless crystals.

References

[1] Patent: US5556853, 1996, A
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 13, p. 2090 - 2099

BOC-L-2-Fluorophe Preparation Products And Raw materials

Raw materials

Di-tert-butyl dicarbonate 2-FLUORO-L-PHENYLALANINE Water Sodium hydroxide

Preparation Products

BOC-L-2-Fluorophe Suppliers

Global( 194)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16512 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
GenicBio Limited 		+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Honest Joy Holdings Limited 		0755-36694831 +8613717124449 sale@feiyang.com.cn China 300 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
Dideu Industries Group Limited 		+86-86-15536356810 +8617392712697 1022@dideu.com China 28755 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
Supplier Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Capot Chemical Co.,Ltd. 		60
GenicBio Limited 		58
career henan chemical co 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Honest Joy Holdings Limited 		58
GL Biochem(Binhai) Ltd. 		58
Dideu Industries Group Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58

View Lastest Price from BOC-L-2-Fluorophe manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Phe(2-F)-OH pictures 2026-07-02 Boc-Phe(2-F)-OH
114873-00-6
 $2.20-8.80 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
BOC-L-2-Fluorophe pictures 2025-04-04 BOC-L-2-Fluorophe
114873-00-6
 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
BOC-L-2-Fluorophe pictures 2019-09-02 BOC-L-2-Fluorophe
114873-00-6
 $7.00 1KG 99% Career Henan Chemical Co
  • Boc-Phe(2-F)-OH pictures
  • Boc-Phe(2-F)-OH
    114873-00-6
  • $2.20-8.80
  • 99%min
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

BOC-L-2-Fluorophe Spectrum

BOC-L-2-Fluorophe(114873-00-6)1HNMR

114873-00-6(BOC-L-2-Fluorophe )Related Search:

tert-Butyl acetate Phenprobamate DL-Phenylalanine EC 2.6.1.2 N-Carbobenzyloxyglycine
N-(tert-Butoxycarbonyl)-L-alanine D-Alanine D-Phenylalanine N-(tert-Butoxycarbonyl)-L-phenylalanine N-Boc-N'-nitro-L-arginine
tert-Butyl peroxyacetate Boc-Aib-OH Fmoc-Phe-OH Fmoc-Lys(Boc)-OH L-Phenylalanine
tert-Butanol BOC-L-PENTAFLUOROPHENYLALANINE (S)-N-Boc-(4-Pyridyl)alanine

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BOC-L-2-FLUOROPHE BOC-L-2-FLUOROPHENYLALANINE BOC-L-PHE(2-F)-OH BOC-O-FLUORO-PHE-OH BOC-PHE(O-F)-OH BOC-PHE(2-F)-OH BOC-(S)-2-AMINO-3-(2'-FLUOROPHENYL)PROPANOIC ACID N-TERT-BUTOXYCARBONYL-2-FLUOROPHENYL-L-ALANINE N-ALPHA-T-BUTOXYCARBONYL-L-2-FLUOROPHENYLALANINE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-2-FLUOROPHENYLALANINE RARECHEM BK PT 0020 (S)-2-TERT-BUTOXYCARBONYLAMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID tert-Butoxycarbonyl-L-2-fluorophenylalanine (S)-N-BOC-2-FLUOROPHENYLALANINE BOC-2-FLUORO-L-PHENYLALANINE L-2-FLUOROPHENYLALANINE, BOC PROTECTED L-2-Fluorophenylalanine, N-BOC protected N-alpha-tert-Butoxycarbonyl-3-(2-fluorophenyl)-L-al N-ALPHA-T-BUTYLOXYCARBONYL-L-2-FLUOROPHENYLALANINE (S)-N-BOC-2-FLUOROPHENYLALANINE 98+% N-tert-Butoxycarbonyl-L-Fluoro Phenylalanine 2-Fluoro-L-phenylalanine,N-BOCprotected (S)-Boc-2-amino-3-(2-fluorophenyl)propionic acid Boc-2-fluoro-L-phenylalanine99% Boc-o-fluoro-L-Phe-OH N-Boc-L-2-fluorophenylalanine,99%e.e. (Tert-Butoxy)Carbonyl L-Phe(2-F)-OH (S)-BOC-2-Fluorophe N-alpha-t-Butyloxycarbonyl-2-fluoro-L-phenylalanine (S)-N-BOC-2-FLUOROPHENYLALANINE, 95%, 98% EE (S)-N-BOC-2-Fluorophenylalanine, 98% ee Boc-L-2-Fluoro-phe-OH BOC-2-FLUORO-L-PHE L-Phenylalanine,N-[(1,1-diMethylethoxy)carbonyl]-2-fluoro- N-Boc-L-2-fluorophenylalanine Boc-2-Fluoro-Phe-OH (Boc-2-Fluoro-L-Phenylalanine) Boc-L-Phe(2-F) -OH Boc-2-Fluoro-L-Phenylalanine Boc-2-fluoro-L-phenylalanine Boc-o-fluoro-Phe-OH N-Boc-2-fluoro-L-phenylalanine, 98% (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(2-fluorophenyl)propanoic acid, N-(tert-Butoxycarbonyl)-3-fluoro-L-phenylalanine (2S)-3-(2-fluorophenyl)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoate BOC-L-2-Fluorophe USP/EP/BP (2S)-3-(2-fluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid (S)-2-((tert-Butoxycarbonyl)aMino)-3-(2-fluorophenyl)propanoic acid 114873-00-6 C14H18FNO4 Specialty Synthesis Phenylalanine Derivatives Peptide Synthesis Unnatural Amino Acid Derivatives Peptide a-amino chiral Phenylalanine analogs and other aromatic alpha amino acids Amino Acids