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2,6-Dichloro-3-fluoroacetophenone

2,6-Dichloro-3-fluoroacetophenone Structure
2,6-Dichloro-3-fluoroacetophenone structure
CAS No.
290835-85-7
Chemical Name:
2,6-Dichloro-3-fluoroacetophenone
Synonyms
1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHANONE;2-chloro-1-(2-chloro-5-fluorophenyl)ethan-1-one;CAS:290835-85-7;Dichloro-3-fluoroacetophe;6'-Dichloro-3'-fluro acetophenone;3-Fluoro-2,6-Dichloroacetophenone;2,6-dichloro-3-fluro acetophenone;2,6-DICHLORO-3-FLUOROACETOPHENONE;2,6-Dichloro-3-fluorobenzophenone;2,6-DICHLORO-5-FLUORO ACETOPHENONE
CBNumber:
CB6374174
Molecular Formula:
C8H5Cl2FO
Molecular Weight:
207.03
MDL Number:
MFCD02093760
MOL File:
290835-85-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:29:15
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2,6-Dichloro-3-fluoroacetophenone Properties

Boiling point 255 °C(lit.)
Density 1.403 g/mL at 25 °C(lit.)
refractive index n20/D 1.529(lit.)
Flash point 255°C
storage temp. Sealed in dry,Room Temperature
form Liquid
Specific Gravity 1.403
color Clear colorless to light yellow
InChI InChI=1S/C8H5Cl2FO/c1-4(12)7-5(9)2-3-6(11)8(7)10/h2-3H,1H3
InChIKey VJBFZHHRVCPAPZ-UHFFFAOYSA-N
SMILES C(=O)(C1=C(Cl)C=CC(F)=C1Cl)C
CAS DataBase Reference 290835-85-7(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,F,T
Risk Statements  36/37/38-22-25
Safety Statements  37/39-26-45
RIDADR  UN 2810 6.1/PG 3
WGK Germany  3
Hazard Note  Flammable
HazardClass  IRRITANT
PackingGroup  III
HS Code  29143990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
REACH Registrations Active
NFPA 704
1
2 0

2,6-Dichloro-3-fluoroacetophenone price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 522945 2′,6′-Dichloro-3′-fluoroacetophenone 98% 290835-85-7 5g $46.8 2023-01-07 Buy
TCI Chemical D2750 2',6'-Dichloro-3'-fluoroacetophenone >97.0%(GC) 290835-85-7 5g $21 2026-04-30 Buy
TCI Chemical D2750 2',6'-Dichloro-3'-fluoroacetophenone >97.0%(GC) 290835-85-7 25g $62 2026-04-30 Buy
ChemScene CS-W020589 1-(2,6-Dichloro-3-fluorophenyl)ethan-1-one ≥96% 290835-85-7 25g $12 2026-06-04 Buy
ChemScene CS-W020589 1-(2,6-Dichloro-3-fluorophenyl)ethan-1-one ≥96% 290835-85-7 500g $54 2026-06-04 Buy
Product number Packaging Price Buy
522945 5g $46.8 Buy
D2750 5g $21 Buy
D2750 25g $62 Buy
CS-W020589 25g $12 Buy
CS-W020589 500g $54 Buy

2,6-Dichloro-3-fluoroacetophenone Chemical Properties, Uses, Production

Synthesis

solution of 1-(2,6-dichloro-3-fluorophenyl)ethanol (1 mmol), zinc bromide (45 mg, 0.2 mmol), and chloramine (282 mg, 1 mmol) in acetonitrile was placed in a three-necked flask equipped with a reflux condenser. The mixture was stirred under reflux for 5 hours and then cooled to room temperature. The reaction mixture was first slowly quenched with water, and then extracted three times with ethyl acetate. The extracted organic solvents were combined, and the resulting organic layer was dried over anhydrous sodium sulfate. The sodium sulfate solid was removed by filtration, and the solvent was removed from the filtrate by vacuum evaporation to obtain the crude product. The residue was purified by silica gel column chromatography to obtain the target product, 2,6-dichloro-3-fluoroacetophenone. Figure 2. Synthetic route of 6-dichloro-3-fluoroacetophenone.

Chemical Properties

clear colorless to light yellow liqui

Uses

2,6-Dichloro-3-fluoroacetophenone is a halogenated derivative of Acetophenone (A164015), a reagent used in the production of fragrances and resin polymers.

Uses

2′,6′-Dichloro-3′-fluoroacetophenone (2,6-Dichloro-3-fluoroacetophenone) may be used to synthesize the enantiomerically pure form of (S)-1-(2,6-dichloro-3-fluorophenyl)ethanol.

General Description

2′,6′-Dichloro-3′-fluoroacetophenone is an aryl fluorinated building block.

2,6-Dichloro-3-fluoroacetophenone synthesis

877397-65-4
290835-85-7
Synthesis of 2,6-Dichloro-3-fluoroacetophenone from (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

2,6-Dichloro-3-fluoroacetophenone Preparation Products And Raw materials

Raw materials

1-(2,6-Dichloro-3-fluorophenyl)ethanol 1,3-Dichloro-4-fluorobenzene Acetyl chloride

Preparation Products

(1S)-1-(2,6-dichloro-3-fluorophenyl)ethyl acetate (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol (R)-1-(2,6-Dichloro-3-fluorophenyl)ethanol

2,6-Dichloro-3-fluoroacetophenone Suppliers

Global Suppliers ( 341)
Supplier Tel Email Country ProdList Advantage
Shanghai Kangtuo Chemical Co., Ltd. 021-69185552 13701777608 kangtuochem@163.com China 4224 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Supplier Advantage
Shanghai Kangtuo Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Ark Pharm, Inc. 56
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56

View Latest Price from 2,6-Dichloro-3-fluoroacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6-Dichloro-3-fluoroacetophenone pictures 2026-06-30 2,6-Dichloro-3-fluoroacetophenone
290835-85-7
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2,6-Dichloro-3-fluoroacetophenone pictures 2025-04-04 2,6-Dichloro-3-fluoroacetophenone
290835-85-7
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2',6'-Dichloro-3'-fluoroacetophenone pictures 2024-11-26 2',6'-Dichloro-3'-fluoroacetophenone
290835-85-7
 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd

2,6-Dichloro-3-fluoroacetophenone Spectrum

2,6-Dichloro-3-fluoroacetophenone(290835-85-7)MS2,6-Dichloro-3-fluoroacetophenone(290835-85-7)1HNMR2,6-Dichloro-3-fluoroacetophenone(290835-85-7)IR1

290835-85-7 (2,6-Dichloro-3-fluoroacetophenone) Related Search:

Trifluoroacetophenone 3-Nitroacetophenone Dichloroacetonitrile 1-(2,6-Difluorophenyl)ethan-1-one 4-Nitroacetophenone
3'-Fluoroacetophenone 4'-Methylacetophenone 4-Fluoroacetophenone Acetophenone 2',6'-Dichloroacetophenone
Chalcone 4'-Hydroxyacetophenone 2-Bromoacetophenone Dichlorofluoroethane 1,3-Dichloro-4-fluorobenzene
2-Chloro-3-fluorotoluene 2'-Chloro-5'-fluoroacetophenone 2-Chloro-3-fluorobenzaldehyde

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2,6-DICHLORO-5-FLUORO ACETOPHENONE 2,6-DICHLORO-3-FLUOROACETOPHENONE 2',6'-Dichloro-3'-Fluoroacetophenone 3-Fluoro-2,6-Dichloroacetophenone 2,6-dichloro-3-fluro acetophenone 2',6'-DICHLORO-3'-FLUOROACETOPHENONE, 98 2',6'-Dichloro-3'-fluoroacetophenone 98% 3-Fluoro-2,6-Dichloroacetophenone 2-chloro-2-(2-chloro-5-fluorophenyl)acetaldehyde 2,6-Dichloro-3-fluoroacetophenone,97% 2',6'-Dichloro-3'-fluoroacetophenone ,99% 6'-Dichloro-3'-fluro acetophenone 2-chloro-1-(2-chloro-5-fluorophenyl)ethan-1-one 2,6-dichloro-3-fluorophenyl ethanone Dichloro-3-fluoroacetophe 1-(2,6-Dichloro-3-fluorophenyl)ethan-1-one, 1-(2,6-Dichloro-3-fluorophenyl)-1-oxoethane 2',6'-Dichloro-3'-fluoroacetophenone> Ethanone, 1-(2,6-dichloro-3-fluorophenyl)- 2',6'-Dichloro-3'-fluoroacetophenone CAS:290835-85-7 2,6-Dichloro-3-fluorobenzophenone 2′,6′-Dichloro-3′-fluoroacetophenone, CAS 290835-85-7 1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHANONE 290835-85-7 Cl2FC6H2COCH3 C8H6Cl2FO C8H5OCl2F C7 to C8 Carbonyl Compounds Building Blocks KETONE Ketones Organic Building Blocks C7 to C8 Carbonyl Compounds Ketones Carbonyl Compounds bc0001