3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
- CAS No.
- 1479-24-9
- Chemical Name:
- 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
- Synonyms
- RMA-126;NSC 166423;ETHYL 2-FLUOROBENZOYLACETATE;Ethyl(2-Fluorobenzoyl)acetate>2-Fluorobenzoylacetic acid ethyl ester;2-[(2-fluorophenyl)-oxomethyl]butanoate;ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-oxo-3-(2-fluorophenyl)propionate;Ethyl 3-(2-fluorophenyl)-3-oxo-propionate;Ethyl (2-fluorobenzoyl)acetate technical grade
- CBNumber:
- CB7331507
- Molecular Formula:
- C11H11FO3
- Molecular Weight:
- 210.2
- MDL Number:
- MFCD00000321
- MOL File:
- 1479-24-9.mol
- MSDS File:
- SDS
| Boiling point | 124-125℃ (1.5 Torr) |
|---|---|
| Density | 1.164 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Liquid |
| pka | 10.03±0.46(Predicted) |
| color | Colorless to Light orange to Yellow |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 225134 | Ethyl (2-fluorobenzoyl)acetate technical grade | 1479-24-9 | 1g | $176 | 2023-06-20 | Buy |
| Sigma-Aldrich | 225134 | Ethyl (2-fluorobenzoyl)acetate technical grade | 1479-24-9 | 10g | $1090 | 2023-06-20 | Buy |
| TCI Chemical | E1097 | Ethyl (2-Fluorobenzoyl)acetate >98.0%(GC)(T) | 1479-24-9 | 5g | $114 | 2025-07-31 | Buy |
| TCI Chemical | E1097 | Ethyl (2-Fluorobenzoyl)acetate >98.0%(GC)(T) | 1479-24-9 | 25g | $398 | 2025-07-31 | Buy |
| TRC | B124908 | Ethyl3-(2-Fluorophenyl)-3-oxopropanoate | 1479-24-9 | 100mg | $60 | 2021-12-16 | Buy |
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Uses,Production
Uses
Ethyl (2-fluorobenzoyl)acetate may be used in chemical synthesis.
Synthesis
64-17-5
223679-79-6
1479-24-9
GENERAL METHOD: An appropriate amount of diketone (9a or 9b) (0.3 mol) was mixed with ethanol (500 mL), heated to 80 °C and refluxed for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure to give the target product ester (10a or 10b) in the form of a red oil. 7.10.1 Preparation of ethyl 3-(2-fluorophenyl)-3-oxopropanoate (10a): the product obtained was a red oily material in 85% yield; mass spectrum (ESI) m/z: 233.1 [M + Na]? , 443.1 [2M + Na]?
References
[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 11, p. 2843 - 2855
[2] Archiv der Pharmazie, 2013, vol. 346, # 7, p. 521 - 533
[3] Patent: EP2799437, 2014, A1. Location in patent: Paragraph 0057
[4] Patent: US2014/364431, 2014, A1. Location in patent: Paragraph 0188
[5] Patent: WO2017/37672, 2017, A1. Location in patent: Page/Page column 48
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai Gubang New Materail Technology Co. LTD | 21-51317962 +8618721305404 | 16728589@qq.com | CHINA | 272 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5661 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
View Lastest Price from 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-20 | 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
1479-24-9
|
US $1.00 / ASSAYS | 1ASSAYS | 99% | KG/T | Career Henan Chemical Co |
-
- 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
1479-24-9
- US $1.00 / ASSAYS
- 99%
- Career Henan Chemical Co
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