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ChemicalBook >> CAS DataBase List >>3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Structure
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine structure
CAS No.
329214-79-1
Chemical Name:
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Synonyms
3-PYRIDINEBORONIC ACID PINACOL ESTER;3-PYRIDYLBORONIC ACID PINACOL ESTER;3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin;AKOS BRN-1142;3-Pyridineboronic;Pyridine-3-boronic acid p...;3-Pyridineboronic Acid PinacoL;3-Pyridine borate pinacol ester,;Pinacolesterpyridinyl-3-boronicacid;3-pyrdineboronic acid pinacol ester
CBNumber:
CB8190239
Molecular Formula:
C11H16BNO2
Molecular Weight:
205.06
MDL Number:
MFCD03084758
MOL File:
329214-79-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:03:54
Product description Number Pack Size Price
3-Pyridineboronic acid pinacol ester 97% 576565 1g $128
3-Pyridineboronic acid pinacol ester 97% 576565 5g $240
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine >98.0%(GC)(T) T2345 1g $22
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine >98.0%(GC)(T) T2345 5g $85
3-Pyridylboronic acid pinacol ester Asreported 287533 2g $393
More product size
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Properties

Melting point 102-104.4 °C(lit.)
Boiling point 300.9±15.0 °C(Predicted)
Density 1.03±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility soluble in Acetone
pka 5.22±0.12(Predicted)
form Crystalline Powder
color White
Water Solubility Insoluble
InChI InChI=1S/C11H16BNO2/c1-10(2)11(3,4)15-12(14-10)9-6-5-7-13-8-9/h5-8H,1-4H3
InChIKey XEMDFESAXKSEGI-UHFFFAOYSA-N
SMILES C1=NC=CC=C1B1OC(C)(C)C(C)(C)O1
CAS DataBase Reference 329214-79-1(CAS DataBase Reference)
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 576565 3-Pyridineboronic acid pinacol ester 97% 329214-79-1 1g $128 2026-04-30 Buy
Sigma-Aldrich 576565 3-Pyridineboronic acid pinacol ester 97% 329214-79-1 5g $240 2026-04-30 Buy
TCI Chemical T2345 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine >98.0%(GC)(T) 329214-79-1 1g $22 2026-04-30 Buy
TCI Chemical T2345 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine >98.0%(GC)(T) 329214-79-1 5g $85 2026-04-30 Buy
Usbiological 287533 3-Pyridylboronic acid pinacol ester Asreported 329214-79-1 2g $393 2026-06-03 Buy
Product number Packaging Price Buy
576565 1g $128 Buy
576565 5g $240 Buy
T2345 1g $22 Buy
T2345 5g $85 Buy
287533 2g $393 Buy

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is an organoborane compound used in the preparation of of polyazatriaryl ligands by sequential borylation/Suzuki-Miyaura coupling. 3-Pyridineboronic Acid Pinacol E ster is used in the preparation of pyrrolo[2,3-b]pyridine derivatives as kinase modulators.

Uses

3-Pyridineboronic Acid Pinacol Ester is an organoborane compound used in the preparation of polyazatriaryl ligands by sequential borylation/Suzuki-Miyaura coupling. 3-Pyridineboronic Acid Pinacol Ester is used in the preparation of pyrrolo[2,3-b]pyridine derivatives as kinase modulators.

Synthesis

3-Chloropyridine

626-60-8

Bis(pinacolato)diboron

73183-34-3

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

329214-79-1

In a nitrogen-protected glove box, a benzene solution of silica-3p-TPP ([P] content 0.11 mmol/g, 45.5 mg, 0.005 mmol P, 1 mol% P), anhydrous degassed benzene (0.8 mL), and [PdCl(η3-cinnamyl)]2 (0.65 mg, 0.00125 mmol, 0.5 mol% Pd) (0.2 mL) was added sequentially to an oven-dried 10 mL glass tube pre-fitted with a magnetic stirrer. After stirring for 5 min, KOAc (147 mg, 1.5 mmol), bis(pinacolato)diboron (2,140 mg, 0.55 mmol) and 3-chloropyridine (63.3 mg, 0.50 mmol) were added sequentially. The reaction tube was sealed with a screw cap and then removed from the glove box, and the reaction was stirred at 25°C for 10 hours. After completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad (eluting with Et2O) and the filtrate was concentrated under reduced pressure. To the residue was added the internal standard 1,1,2,2-tetrachloroethane, and the yield of the product 3-pyridineboronic acid pinacol ester was 95% as determined by 1H NMR. The crude product was purified by silica gel column chromatography to afford the target compound 3-pyridineboronic acid pinacol ester (87.0 mg, 0.40 mmol, 80% yield).

References

[1] ChemCatChem, 2014, vol. 6, # 5, p. 1340 - 1348
[2] RSC Advances, 2018, vol. 8, # 25, p. 13643 - 13648
[3] Angewandte Chemie - International Edition, 2007, vol. 46, # 28, p. 5359 - 5363
[4] Chemistry Letters, 2014, vol. 43, # 5, p. 584 - 586
[5] Patent: WO2010/110782, 2010, A1. Location in patent: Page/Page column 46-47

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine synthesis

626-55-1
73183-34-3
329214-79-1
Synthesis of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine from 3-Pyridyl bromide and Bis(pinacolato)diboron

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Preparation Products And Raw materials

Raw materials

Tris(3-pyridyl)boroxin 3-Butanoylpyridine (DIMETHYLPHENYLSILYL)BORONIC ACID PINAC& 3-Iodopyridine 3-Pyridyl bromide
3-Aminopyridine Pinacol Nicotinic acid Pinacolborane 3-Chloropyridine
Bis(pinacolato)diboron

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Preparation Products

Abiraterone acetate 4-Pyridineboronic acid pinacol ester Pyridine

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Suppliers

Global( 274)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20111 58
Springchem New Material Technology Co.,Limited 		+86-021-62885108 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 14032 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32998 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
Shanghai Arbor Chemical Co., Ltd. 		021-60451682 act@arborchemical.com CHINA 903 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Accela ChemBio Inc. 		+1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63645 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shanghai Arbor Chemical Co., Ltd. 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58

View Lastest Price from 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine pictures 2026-08-10 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
329214-79-1
 $1.00-200.00 1KG 99%, 99.5% Sublimated Henan Fengda Chemical Co., Ltd
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine pictures 2021-07-13 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
329214-79-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine pictures 2021-07-10 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
329214-79-1
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Spectrum

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine(329214-79-1)1HNMR3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine(329214-79-1)FT-IR

329214-79-1(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine)Related Search:

3-Pyridylboronic acid Pyridine-4-boronic acid ISONICOTINOYL CHLORIDE HYDROCHLORIDE 4-Pyridineboronic acid pinacol ester 3-Amino-5-bromopyridine
6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester 2-METHOXYPYRIDINE-5-BORONIC ACID PINACOL ESTER 4-Isoquinolineboronic acid pinacol ester 2-(2-Chloro-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine 4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
2,2-DIMETHYL-N-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PROPIONAMIDE 2-Aminopyridine-5-boronic acid, pinacol ester 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-CHLORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 2,6-DIMETHOXY-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
3-CHLORO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE 5-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine,3-BROMO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE 2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE

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3-Pyridineboronic acid pinacol ester 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 3-Pyridineboronic acid pinacol ester 97% 3-PYRIDYLBORONIC ACID PINACOL ESTER AKOS BRN-1142 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE 2-(3-PYRIDYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE PYRIDIN-3-YLBORONIC ACID PINACOL ESTER PYRIDINE-3-BORONIC ACID, PINACOL ESTER 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin 3-Pyridineboronic Pinacolesterpyridinyl-3-boronicacid 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 3-Pyridylboronic acid pinacol ester 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine ,98% 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine,97% 3-Pyridineboronic acid pinacol ester ,98% Pyridine-3-boronic acid p... 2-(3-Pyridyl)-4,4,5,5-tetraMethyl-1,3-dioxaborolane 4,4,5,5-TetraMethyl-2-(3-pyridinyl)-1,3,2-dioxaborolane 4,4,5,5-TetraMethyl-2-(3-pyridyl)-1,3,2-dioxaborolane 4,4,5,5-TetraMethyl-2-(pyridin-3-yl)-1,3,2-dioxaborolane 2-(3-Pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3-Pyridylboronic Acid Pinacol Ester 3-pyrdineboronic acid pinacol ester 3-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 2-(Pyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Pyridine,3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- 3-Pyridineboronic Acid PinacoL 3-Pyridinylboronic acid pinacol ester Pyridine-3-boronic acid pinacol ester - [P7416] 3-PYRIDINEBORONIC ACID PINACOL ESTER 3-Pyridine borate pinacol ester, 3-(4,4,5,5-TETRA METHYL-1,3,2-DIOXABORALAN-2-YL) PYRIDINE-2,4,5,6-D4 329214-79-1 Boronate Esters Boronic Acids and Derivatives Organometallic Reagents Heteroaryl ps B (Classes of Boron Compounds) Boronic Acids Esters Boronic acid