Etilefrine hydrochloride
- CAS No.
- 943-17-9
- Chemical Name:
- Etilefrine hydrochloride
- Synonyms
- ETILEFRINE HCL;Epholin;Funasol;Efortil;Efotinon;Ehochlon;Circupon;Effontil;Effortil;Kertasin
- CBNumber:
- CB9268575
- Molecular Formula:
- C10H15NO2.ClH
- Molecular Weight:
- 217.69
- MDL Number:
- MFCD00060167
- MOL File:
- 943-17-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 122 °C |
|---|---|
| storage temp. | -20°C |
| solubility | Freely soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride |
| form | Solid |
| color | White to off-white |
| InChI | InChI=1S/C10H15NO2.ClH/c1-2-11-7-10(13)8-4-3-5-9(12)6-8;/h3-6,10-13H,2,7H2,1H3;1H |
| InChIKey | KTNROWWHOBZQGK-UHFFFAOYSA-N |
| SMILES | Cl.OC1=CC=CC(=C1)C(O)CNCC |
| FDA UNII | ZBI6Q5FH3S |
| UNSPSC Code | 51101500 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H412 | |||||||||
| Precautionary statements | P273-P301+P310+P330 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| RTECS | DO5618000 | |||||||||
| HS Code | 2922290090 | |||||||||
| NFPA 704 |
|
Etilefrine hydrochloride price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E2451000 | Etilefrine hydrochloride European Pharmacopoeia (EP) Reference Standard | 943-17-9 | 75 mg | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | E2451000 | Etilefrine hydrochloride European Pharmacopoeia (EP) Reference Standard | 943-17-9 | e2451000 | $153 | 2024-03-01 | Buy |
| TCI Chemical | E0381 | Etilefrine Hydrochloride | 943-17-9 | 5G | $96 | 2026-04-30 | Buy |
| TCI Chemical | E0381 | Etilefrine Hydrochloride | 943-17-9 | 25G | $290 | 2026-04-30 | Buy |
| Cayman Chemical | 33249 | Etilefrine (hydrochloride) ≥98% | 943-17-9 | 250mg | $49 | 2026-04-30 | Buy |
Etilefrine hydrochloride Chemical Properties, Uses, Production
Chemical Properties
White or almost white, crystalline powder or colourless crystals.
Originator
Circupon,Troponwerke,W. Germany
Uses
Adrenoceptor agonist.
Definition
ChEBI: Etilefrine hydrochloride (TN) is a member of phenols.
Manufacturing Process
30 parts of 1-(3'-hydroxyphenyl)-2-(N-benzylaminomethyl)-ethan-1-one are
mixed with 100 parts of pyridine and 30 parts of pivalic anhydride and
dissolved while warming. After heating for 1 hour under reflux, the acylation
is complete. After concentrating the reaction solution, the product is
precipitated from acetone/ether. Yield: 96.4% of 1-(3'-pivaloyloxyphenyl)-2-
(N-benzylaminomethyl)-ethan-1-one.
3 parts of palladium/charcoal (10% strength) are prehydrogenated in water,
thereafter 10 parts of 1-(3'-pivaloyloxyphenyl)-2-(N-benzylaminoethyl)-ethan-
1-one, dissolved in a 10-fold amount of water, are added dropwise at room
temperature and hydrogenation is carried out until 1 mol of hydrogen has
been taken up. After filtering off the catalyst, a further 3 parts of
palladium/charcoal are added and hydrogenation is carried out until a further
mol of hydrogen has been taken up. The catalyst is separated off and after
removal of the solvent the hydrogenation product is reprecipitated from
acetone/petroleum ether and from methanol/ether until it is pure according to
thin layer chromatography. Yield: 38.8% of 1-(3'-pivaloyloxyphenyl)-2-
ethylaminoethanol-1 hydroxide, melting point 208°C to 209°C.
Therapeutic Function
Tranquilizer
Etilefrine hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9413 | 50 |
View Latest Price from Etilefrine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-20 | Etilefrine hydrochloride
943-17-9
|
1kg | 98%-101%; EP | 50kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-28 | Tilefrine Hydrochloride
943-17-9
|
$20.00-50.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-12-24 | Etilefrine hydrochloride
943-17-9
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Etilefrine hydrochloride
943-17-9
- 98%-101%; EP
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Tilefrine Hydrochloride
943-17-9
- $20.00-50.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Etilefrine hydrochloride
943-17-9
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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