Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2,2-Diethoxyethylamine

2,2-Diethoxyethylamine

2,2-Diethoxyethylamine Structure
2,2-Diethoxyethylamine structure
CAS No.
645-36-3
Chemical Name:
2,2-Diethoxyethylamine
Synonyms
2,2-diethoxyethan-1-aMine;AMINOACETALDEHYDE DIETHYL ACETAL;2,2-Diethoxyethanamine;Aminoacetaldehyde;AMINOACETAL;B-AMINOACETAL;Acetalylamine;2-Aminoethanal;Aminoacetal >RARECHEM AL BW 2181
CBNumber:
CB9446720
Molecular Formula:
C6H15NO2
Molecular Weight:
133.19
MDL Number:
MFCD00008136
MOL File:
645-36-3.mol
MSDS File:
SDS
Last updated:2026-05-28 04:51:17
Request For Quotation

2,2-Diethoxyethylamine Properties

Melting point -78
Boiling point 162-163 °C (lit.)
Density 0.916 g/mL at 25 °C (lit.)
refractive index n20/D 1.417(lit.)
Flash point 114 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka pK1:8.47(+1) (25°C)
form clear liquid
color Colorless to Light yellow
Water Solubility soluble
BRN 506067
InChI 1S/C6H15NO2/c1-3-8-6(5-7)9-4-2/h6H,3-5,7H2,1-2H3
InChIKey HJKLEAOXCZIMPI-UHFFFAOYSA-N
SMILES CCOC(CN)OCC
CAS DataBase Reference 645-36-3(CAS DataBase Reference)
FDA UNII 658AO12BQL
NIST Chemistry Reference Ethanamine, 2,2-diethoxy-(645-36-3)
EPA Substance Registry System Ethanamine, 2,2-diethoxy- (645-36-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)
GHS02,GHS05
Signal word  Danger
Hazard statements  H226-H314
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,C,F
Risk Statements  10-36/37/38-34
Safety Statements  23-24/25-26-45-36/37/39-16-36
RIDADR  UN 1989 3/PG 3
WGK Germany  3
Hazard Note  Irritant
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29225090
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1B
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
2 0

2,2-Diethoxyethylamine price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A37200 Aminoacetaldehyde diethyl acetal 98% 645-36-3 25ml $152 2026-04-30 Buy
Sigma-Aldrich A37200 Aminoacetaldehyde diethyl acetal 98% 645-36-3 100ml $335 2026-04-30 Buy
TCI Chemical A0247 Aminoacetal >97.0%(GC)(T) 645-36-3 25mL $53 2026-04-30 Buy
TCI Chemical A0247 Aminoacetal >97.0%(GC)(T) 645-36-3 250mL $367 2026-04-30 Buy
Usbiological 441379 Aminoacetaldehyde Diethyl Acetal 645-36-3 5ml $312 2026-06-03 Buy
Product number Packaging Price Buy
A37200 25ml $152 Buy
A37200 100ml $335 Buy
A0247 25mL $53 Buy
A0247 250mL $367 Buy
441379 5ml $312 Buy

2,2-Diethoxyethylamine Chemical Properties, Uses, Production

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW LIQUID

Uses

Aminoacetaldehyde diethyl acetal, is used as an agrochemical intermediate, pharmaceutical, syntheses material intermediate.

Synthesis

There are two main methods of synthesizing aminoacetaldehyde diethyl acetal as follows:

(1) 2-(2-azidoethyl)-1,3-dioxolane is generated from 2-(2-azidoethyl)-1,3-dioxolane by refluxing 2-(2-azidoethyl)-1,3-dioxolane with sodium azide over a phase transfer catalyst, which is further reacted with triphenylphosphine/water, but the NaN3 compounds are highly poisonous and explosive, which is not conducive to industrialized production.

(2) 2-(2-bromoethyl)-1,3-dioxolane is obtained by ion exchange with a macroporous quaternary ammonium Amberlite resin ( AmberliteIRA 900) that has been attached to a negative nitrite ion to obtain 2-(2-nitrosoethyl)-1,3-dioxolane, which is then catalyzed by platinum oxidation to obtain aminoglycolaldehyde diethyl acetal by platinum oxidation catalyst, which has a low yield.

2,2-Diethoxyethylamine synthesis

105-57-7
645-36-3
Synthesis of 2,2-Diethoxyethylamine from Acetal

2,2-Diethoxyethylamine Preparation Products And Raw materials

Raw materials

Diethanol Chloroacetaldehyde 1,1-Diethoxy-2-iodoethane 2-Azido-1,1-diethoxyethane 2,2-diethoxyacetaldehyde
2,2-Diethoxyacetamide 1,1-Diethoxy-2-nitroethane Diethoxyacetonitrile Ethyl diethoxyacetate Acetal
Bromoacetaldehyde diethyl acetal

1of3

Preparation Products

2-Aminoimidazole 2-Nitroimidazole 8-Bromoisoquinoline Methimazole N-(2,2-diethoxyethyl)-2,2-diethoxy-ethanamine
Diacetamide 1-Phenylimidazoline-2-thione 1-Ethyl-1H-imidazole-2-thiol 2-(1H-Imidazol-2-yl)-pyrazine

1of2

2,2-Diethoxyethylamine Suppliers

Global Suppliers ( 370)
Supplier Tel Email Country ProdList Advantage
Henan Chongyi Biomedicine Co., Ltd 18257818007 779340002@qq.com China 41 58
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. 021-69106960 13701823997 13701823733@163.com China 4634 60
shanghaidelaikekejiyouxiangongsi 17351445187 3528434302@qq.com China 282 58
Shanghai zhiping biology science and technology co., ltd 13621780388 494972302@qq.com China 39 58
Creasyn Finechem(Tianjin) Co., Ltd. 022-83946278 13820372920 sales@creasyn.com China 968 68
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Supplier Advantage
Henan Chongyi Biomedicine Co., Ltd 58
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. 60
shanghaidelaikekejiyouxiangongsi 58
Shanghai zhiping biology science and technology co., ltd 58
Creasyn Finechem(Tianjin) Co., Ltd. 68
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Beijing Ouhe Technology Co., Ltd 60

View Latest Price from 2,2-Diethoxyethylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2-Diethoxyethylamine pictures 2025-06-27 2,2-Diethoxyethylamine
645-36-3
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
2,2-Diethoxyethylamine pictures 2025-06-20 2,2-Diethoxyethylamine
645-36-3
 $15.00-40.00 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
2,2-Diethoxyethylamine pictures 2022-09-27 2,2-Diethoxyethylamine
645-36-3
 $28.00-30.00 1Kg 99.0% up 50 tons per month Xinxiang Hongqi District Houyuan Trading Co.,Ltd

2,2-Diethoxyethylamine Spectrum

2,2-Diethoxyethylamine(645-36-3)MS2,2-Diethoxyethylamine(645-36-3)1HNMR2,2-Diethoxyethylamine(645-36-3)13CNMR2,2-Diethoxyethylamine(645-36-3)IR12,2-Diethoxyethylamine(645-36-3)Raman

645-36-3 (2,2-Diethoxyethylamine) Related Search:

3,3-Diethoxypropionitrile Monoethanolamine 2-(2-Aminothiazol-4-yl)glyoxylic acid Chloroacetaldehyde diethyl acetal 1,1-Dimethoxyethane
Bromoacetaldehyde dimethyl acetal Acrolein diethyl acetal Bromoacetaldehyde diethyl acetal Aminoacetaldehyde dimethyl acetal Diethyl phthalate
2-(4-Aminophenyl)ethanol 4,4-Diethoxybutylamine Acetylacetaldehyde dimethyl acetal Acetal Diethyl malonate
Trimethylstearylammonium Chloride 2,6-Di-tert-butylnaphthalene sulfonic acid sodium salt Benzyl carbamate

1of4

2,2-diethoxy-ethanamin 2,2-Diethyloxyethylamine Acetaldehyde, amino-, diethyl acetal 1-AMINO-2,2-DIETHOXYETHANE B-AMINOACETAL Aminoacetaldehydediethylacetal,98% β,β-diethoxyethylamine ,2-Diethoxyethylamine 1,1-Diethoxy-2-aminoethane 2-Aminoethanal AMINOACETALDEHYDE DIETHYL ACETAL 98% Aminoacetaldehyde diethyl acetal,99% Aminoacetaldehyde diethyl acetal,2,2-Diethoxyethylamine AMinoacetaldehyde diethyl acetal, 99% 5ML 2,2-Diethoxyethylamine, 2-Amino-1,1-diethoxyethane AMinoacetaldehyde Diethyl Acetal, 97+% AMino acetaldehyde condensation two ethanol 2-Aminoacetaldehyde diethylacetal for synthesis Aminoacetaldehyde diethyleacetal Acetalylamine alpha-Aminoacetaldehyde diethyl acetal beta-Aminoacetaldehyde diethyl acetal Glycinaldehyde diethyl acetal RARECHEM AL BW 2181 2-AMINOACETALDEHYDE DIETHYLACETAL 2,2-DIETHOXYETHYLAMINE TIMTEC-BB SBB004213 Aminoacetal > 2,2-Diethoxyethylamine ISO 9001：2015 REACH 2,2-Diethoxyethanamine 2,2-diethoxyethan-1-aMine AMINOACETAL AMINOACETALDEHYDE DIETHYL ACETAL Aminoacetaldehyde 645-36-3 645-36-4 H2NHC2CHOCH2CH32 CHOCH2CH32CH2NH2 NH2CH2CHOC2H52 AMINE Building Blocks Organic Building Blocks Acetals/Ketals/Ortho Esters Oxygen Compounds Pharmaceutical Intermediates Small molecule bc0001