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2-Aminobenzenesulfonamide

2-Aminobenzenesulfonamide structure

CAS No.: 3306-62-5

Chemical Name:: 2-Aminobenzenesulfonamide

Synonyms: orthanilamide;o-sulfanilamide;2-Sulphamoylaniline;2-Aminobenzenesulfamide;2-Amino-benzenesulfomide;2-Aminobenzenesulfonamde;2-amino-benzenesulfonamid;o-aminobenzenesulfonamide;o-amino-benzenesulfonamid;2-AMINOBENZENESULFONAMIDE

CBNumber:: CB9853506

Molecular Formula:: C6H8N2O2S

Molecular Weight:: 172.2

MDL Number:: MFCD00007932

MOL File:: 3306-62-5.mol

Last updated:2025-10-02 16:35:48

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2-Aminobenzenesulfonamide Properties

Melting point	155-157 °C(lit.)
Boiling point	392.7±44.0 °C(Predicted)
Density	1.3250 (rough estimate)
refractive index	1.6490 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Sparingly), Methanol (Slightly)
pka	10.29±0.60(Predicted)
form	Solid
color	Off-White to Beige
Water Solubility	6.655g/L(24 ºC)
InChI	InChI=1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChIKey	YAZSBRQTAHVVGE-UHFFFAOYSA-N
SMILES	C1(S(N)(=O)=O)=CC=CC=C1N
CAS DataBase Reference	3306-62-5(CAS DataBase Reference)
FDA UNII	YME8QXY8ED
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

36/37/39-26-22-36

WGK Germany

RTECS

DA9449000

Hazard Note

Irritant

HS Code

29350090

NFPA 704

	1
2		0

2-Aminobenzenesulfonamide price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	245887	2-Aminobenzenesulfonamide 98%	3306-62-5	5g	$53.9	2025-07-31	Buy
Sigma-Aldrich	245887	2-Aminobenzenesulfonamide 98%	3306-62-5	25g	$218	2023-06-20	Buy
TRC	B401505	2-Aminobenzenesulfonamide	3306-62-5	100mg	$70	2021-12-16	Buy
Biosynth Carbosynth	FA50763	2-Aminobenzenesulfonamide	3306-62-5	10g	$79.1	2021-12-16	Buy
ChemScene	CS-7986	2-Aminobenzenesulfonamide 99.80%	3306-62-5	10g	$60	2021-12-16	Buy

Product number	Packaging	Price	Buy
245887	5g	$53.9	Buy
245887	25g	$218	Buy
B401505	100mg	$70	Buy
FA50763	10g	$79.1	Buy
CS-7986	10g	$60	Buy

2-Aminobenzenesulfonamide Chemical Properties,Uses,Production

Chemical Properties

white to pale cream crystalline powder or crystals

Uses

Diuretic;Inhibitor of carbonic anhydrase B

Definition

ChEBI: 2-aminobenzenesulfonamide is a sulfonamide and a member of benzenes.

Synthesis

5455-59-4

3306-62-5

General procedure for the synthesis of o-aminobenzenesulfonamide from 2-nitrobenzenesulfonamide: 2-nitrobenzenesulfonamide (80.0 g, 0.58 mol) was dissolved in methanol in the presence of a Pd/C catalyst (10.0 g, 13% w/w) to prepare a solution with a mass concentration of 10%. The hydrogenation reaction was carried out at 50 psi hydrogen pressure and 60°C and the reaction was continued overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to give 60 g of off-white solid o-aminobenzenesulfonamide in 95% yield.

IC 50

CA Ⅸ

Solubility in organics

2-Aminobenzenesulfonamide is freely soluble in water, glacial acetic acid, ethyl alcohol, acetone, and methanol; insoluble in benzene.

References

[1] Patent: CN104761514, 2016, B. Location in patent: Paragraph 0028-0030
[2] Tetrahedron Letters, 2001, vol. 42, # 33, p. 5601 - 5603
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 7, p. 2455 - 2478
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 17, p. 5647 - 5647
[5] Bihang till Svenska Vet.-Akad. Handlingar, vol. 27, p. II, No. 1, S. 4

2-Aminobenzenesulfonamide synthesis

Synthesis of 2-Aminobenzenesulfonamide from 2-Nitrobenzenesulfonamide

2-Aminobenzenesulfonamide Preparation Products And Raw materials

Raw materials

Iron filings Hydrazinium hydroxide solution Ethanol Palladium 2-Nitrobenzenesulfonamide

2-benzyl-1,1-dioxo-4H-1$l^{6},2,4-benzothiadiazin-3-one Methanol Hydrogen Activated carbon

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Preparation Products

N,N'-DIACETYLSULFANILAMIDE 2H-1,2,4-Benzothiadiazine 1,1-dioxide Benzenesulfonamide, 2-hydrazino- (9CI) 2-Amino-5-bromobenzenesulfonamide 2-IODOBENZENE-1-SULFONAMIDE, 95%+

2-Aminobenzenesulfonamide Suppliers

Global( 233)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8772	58
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32433	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2783	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	20342	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Longyan Tianhua Biological Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CD Chemical Group Limited	58

View Lastest Price from 2-Aminobenzenesulfonamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-11	2-Aminobenzenesulfonamide 3306-62-5	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-09-30	Orthanilamide 3306-62-5	US $138.00 / mg		99.96%	10g	TargetMol Chemicals Inc.
2019-07-06	2-Aminobenzenesulfonamide 3306-62-5	US $522.00 / KG	1KG	98%	1T	Career Henan Chemical Co

2-Aminobenzenesulfonamide
3306-62-5
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Orthanilamide
3306-62-5
US $138.00 / mg
99.96%
TargetMol Chemicals Inc.

2-Aminobenzenesulfonamide
3306-62-5
US $522.00 / KG
98%
Career Henan Chemical Co

2-Aminobenzenesulfonamide Spectrum

2-Aminobenzenesulfonamide(3306-62-5)¹HNMR 2-Aminobenzenesulfonamide(3306-62-5)¹³CNMR 2-Aminobenzenesulfonamide(3306-62-5)IR1 2-Aminobenzenesulfonamide(3306-62-5)IR2 2-Aminobenzenesulfonamide(3306-62-5)Raman

3306-62-5(2-Aminobenzenesulfonamide)Related Search:

Methyl anthranilate o-Anisidine Sulfanilic acid Benzenesulfonamide 2-Aminobenzaldehyde

4-Aminobenzoic acid 4-AMINOBENZENESULFONAMIDE(SULFANILAMIDE),P-AMINOBENZENESULFONAMIDE,Aminobenzenesulfonamide,4-AMINOBENZENESULFONAMIDE Anthranilic acid 3-AMINOBENZENESULFONAMIDE: TECH., 80%,3-Aminobenzenesulfonamide97%,3-AMINOBENZENESULFONAMIDE,M-AMINOBENZENESULFONAMIDE Hydrochlorothiazide

N-Ethyl-N-phenyl-o-aminobenzenesulfonamide BENZTHIAZIDE 4-Amino-6-chlorobenzene-1,3-disulfonamide Trichlormethiazide BENDROFLUMETHIAZIDE

Althiazide DIAZOXIDE Clorsulon

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2-amino-benzenesulfonamid Benzenesulfonamide, 2-amino- (9CI) 2-Aminobenzenesulfonamide ,98% 2-Aminobenzenesulfamide 2-Sulphamoylaniline 2-AMinobenzenesulfonaMide, 98% 5GR 2-Aminobenzenesulfonamde 2-Amino-benzenesulfomide o-amino-benzenesulfonamid o-aminobenzenesulfonamide orthanilamide o-sulfanilamide o-Aminobenzenesulphonamide 2-AMINOBENZENESULFONAMIDE 2-AMINO-BENZENESULFONYL CHLORIDE 2-AMINOBENZENE SULPHONAMIDE 2-AMINOPHENYL SULFONYL CHLORIDE 2-Amino-Benzensulfonamide D-aminobenzene sulfonamide Benzenesulfonamide, 2-amino- 2-Aminobenzenesulfonamide ISO 9001：2015 REACH 2-Aminobenzenesulfonamide Orthanilamide, 10 mM in DMSO 3306-62-5 3360-62-5 3362-62-5 Building Blocks Organic Building Blocks Sulfonamides/Sulfinamides Sulfur Compounds Inhibitors Sulphur Derivatives Benzene derivates Organic Building Blocks Sulfonamides/Sulfinamides Sulfur Compounds SULFONAMIDE Intermediates of Dyes and Pigments