2-Aminobenzenesulfonamide
- CAS No.
- 3306-62-5
- Chemical Name:
- 2-Aminobenzenesulfonamide
- Synonyms
- orthanilamide;o-sulfanilamide;2-Sulphamoylaniline;2-Aminobenzenesulfamide;2-Amino-benzenesulfomide;2-Aminobenzenesulfonamde;2-amino-benzenesulfonamid;o-aminobenzenesulfonamide;o-amino-benzenesulfonamid;2-AMINOBENZENESULFONAMIDE
- CBNumber:
- CB9853506
- Molecular Formula:
- C6H8N2O2S
- Molecular Weight:
- 172.2
- MDL Number:
- MFCD00007932
- MOL File:
- 3306-62-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 155-157 °C(lit.) |
|---|---|
| Boiling point | 392.7±44.0 °C(Predicted) |
| Density | 1.3250 (rough estimate) |
| refractive index | 1.6490 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| pka | 10.29±0.60(Predicted) |
| form | Solid |
| color | Off-White to Beige |
| Water Solubility | 6.655g/L(24 ºC) |
| InChI | InChI=1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) |
| InChIKey | YAZSBRQTAHVVGE-UHFFFAOYSA-N |
| SMILES | C1(S(N)(=O)=O)=CC=CC=C1N |
| CAS DataBase Reference | 3306-62-5(CAS DataBase Reference) |
| FDA UNII | YME8QXY8ED |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 36/37/39-26-22-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DA9449000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29350090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2-Aminobenzenesulfonamide price More Price(83)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 245887 | 2-Aminobenzenesulfonamide 98% | 3306-62-5 | 5g | $53.9 | 2025-07-31 | Buy |
| Sigma-Aldrich | 245887 | 2-Aminobenzenesulfonamide 98% | 3306-62-5 | 25g | $218 | 2023-06-20 | Buy |
| Usbiological | 260887 | 2-Aminobenzenesulfonamide Asreported | 3306-62-5 | 10g | $360 | 2026-06-03 | Buy |
| Usbiological | 260887 | 2-Aminobenzenesulfonamide Asreported | 3306-62-5 | 25g | $555 | 2026-06-03 | Buy |
| Usbiological | 260887 | 2-Aminobenzenesulfonamide Asreported | 3306-62-5 | 50g | $859 | 2026-06-03 | Buy |
2-Aminobenzenesulfonamide Chemical Properties, Uses, Production
Chemical Properties
white to pale cream crystalline powder or crystals
Uses
Diuretic;Inhibitor of carbonic anhydrase B
Definition
ChEBI: 2-aminobenzenesulfonamide is a sulfonamide and a member of benzenes.
Synthesis
5455-59-4
3306-62-5
General procedure for the synthesis of o-aminobenzenesulfonamide from 2-nitrobenzenesulfonamide: 2-nitrobenzenesulfonamide (80.0 g, 0.58 mol) was dissolved in methanol in the presence of a Pd/C catalyst (10.0 g, 13% w/w) to prepare a solution with a mass concentration of 10%. The hydrogenation reaction was carried out at 50 psi hydrogen pressure and 60°C and the reaction was continued overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to give 60 g of off-white solid o-aminobenzenesulfonamide in 95% yield.
IC 50
CA Ⅸ
Solubility in organics
2-Aminobenzenesulfonamide is freely soluble in water, glacial acetic acid, ethyl alcohol, acetone, and methanol; insoluble in benzene.
References
[1] Patent: CN104761514, 2016, B. Location in patent: Paragraph 0028-0030
[2] Tetrahedron Letters, 2001, vol. 42, # 33, p. 5601 - 5603
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 7, p. 2455 - 2478
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 17, p. 5647 - 5647
[5] Bihang till Svenska Vet.-Akad. Handlingar, vol. 27, p. II, No. 1, S. 4
2-Aminobenzenesulfonamide Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai wencai New Material Technology Co., Ltd. | 15721586846 | wencaimat@163.com | China | 2792 | 58 |
| Quzhou HuntBio Co., Ltd. | 0571-64067827 13372408495 | sales@huntchem.com | China | 76 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| jiliang chemicals | 21-62165282 | bidingchem@163.com | China | 1395 | 60 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 |
View Latest Price from 2-Aminobenzenesulfonamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Orthanilamide
3306-62-5
|
$138.00 | 99.72% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | 2-Aminobenzenesulfonamide
3306-62-5
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2019-07-06 | 2-Aminobenzenesulfonamide
3306-62-5
|
$522.00 | 1KG | 98% | 1T | Career Henan Chemical Co |
-
- Orthanilamide
3306-62-5
- $138.00
- 99.72%
- TargetMol Chemicals Inc.
-
- 2-Aminobenzenesulfonamide
3306-62-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-Aminobenzenesulfonamide
3306-62-5
- $522.00
- 98%
- Career Henan Chemical Co
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