|
|
| | 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one Basic information |
| Product Name: | 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one | | Synonyms: | 2,3-dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-1h-inden-1-one;5,6-DIMETHOXY-2-(PYRIDINE-4-YL)METHYLENE-INDAN-1-ONE;4-[(5,6-Dimethoxy-1-Indanone) -2-Methyl] Pyridine;1-Indanone,5,6-dimethoxy-2-(4-pyridylmethylene)- (7CI,8CI);Donepezil pyridine dehydro Imp;Doneprzil Pyridine Dehydro Imp;5,6-dimethoxyl-2-(piperidin-4-y)methylene-indan-1-one;5,6-DIMETHOXY-2-(4-PYRIDYLMETHYLENE)-1-INDANONE,98.0+% | | CAS: | 4803-74-1 | | MF: | C17H15NO3 | | MW: | 281.31 | | EINECS: | 1312995-182-4 | | Product Categories: | Aromatics Compounds;Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;4803-74-1 | | Mol File: | 4803-74-1.mol |  |
| | 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one Chemical Properties |
| Melting point | 210-211°C | | Boiling point | 499.9±45.0 °C(Predicted) | | density | 1.255 | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 5.10±0.10(Predicted) | | color | Yellow | | CAS DataBase Reference | 4803-74-1(CAS DataBase Reference) |
| | 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | An impurity of Donepezil. | | References | [1] Patent: WO2012/131540, 2012, A1. Location in patent: Page/Page column 16
[2] Patent: US2004/143121, 2004, A1. Location in patent: Page 3
[3] Patent: WO2004/82685, 2004, A1. Location in patent: Page/Page column 9
[4] European Journal of Medicinal Chemistry, 2011, vol. 46, # 11, p. 5694 - 5697
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 23, p. 7029 - 7035,7 |
| | 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one Preparation Products And Raw materials |
|