Thalidomide-linker 15 manufacturers
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| | Thalidomide-linker 15 Basic information |
| Product Name: | Thalidomide-linker 15 | | Synonyms: | Thalidomide-linker 15;Thalidomide-O-amido-C6-NH2 hydrochloride;-oxyacetamide-alkylC6-amine;N-(6-Aminohexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride;ThalidomideOamidoC6NH2 hydrochloride,Inhibitor,inhibit,E3 Ligase Ligand-Linker Conjugates,Thalidomide-O-amido-C-6-NH2 hydrochloride,Thalidomide O amido C6 NH2 hydrochloride;Thalidomide 4'-oxyacetamide-alkylC6-amine;Thalidomide-O-amido-C6-NH2 HCl;Acetamide, N-(6-aminohexyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, hydrochloride (1:1) | | CAS: | 2376990-31-5 | | MF: | C21H27ClN4O6 | | MW: | 466.92 | | EINECS: | | | Product Categories: | | | Mol File: | 2376990-31-5.mol |  |
| | Thalidomide-linker 15 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | Thalidomide-linker 15 Usage And Synthesis |
| Uses | Thalidomide-O-amido-C6-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. | | IC 50 | Cereblon | | storage | Store at -20°C | | References | [1] Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1 |
| | Thalidomide-linker 15 Preparation Products And Raw materials |
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