| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:Thalidomide-O-C1-amido-PEG-C2-NH2 HCl
CAS:2204226-02-6
Purity:待询 Package:待询 Remarks:212173(Component:2022182-59-6)
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Thalidomide-linker 13 manufacturers
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| | Thalidomide-linker 13 Basic information |
| Product Name: | Thalidomide-linker 13 | | Synonyms: | Thalidomide-linker 13;Thalidomide-O-amido-PEG-C2-NH2 hydrochloride;-oxyacetamide-PEG1-amine;Thalidomide-O-amido-PEG1-NH2 hydrochloride;N-(2-(2-Aminoethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride;Thalidomide-O-amido-PEG1-NH2.HCl;Inhibitor,Thalidomide-O-amido-PEG-C-2-NH2 hydrochloride,ThalidomideOamidoPEGC2NH2 hydrochloride,inhibit,Thalidomide O amido PEG C2 NH2 hydrochloride,E3 Ligase Ligand-Linker Conjugates;Thalidomide-O-C1-amido-PEG-C2-NH2 HCl | | CAS: | 2204226-02-6 | | MF: | C19H23ClN4O7 | | MW: | 454.86 | | EINECS: | | | Product Categories: | peg | | Mol File: | 2204226-02-6.mol |  |
| | Thalidomide-linker 13 Chemical Properties |
| storage temp. | 2-8°C, sealed storage, away from moisture | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | Thalidomide-linker 13 Usage And Synthesis |
| Uses | Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. | | IC 50 | Cereblon | | storage | Store at -20°C | | References | [1] Chessum NEA, et al. Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766). J Med Chem. 2018 Feb 8;61(3):918-933. DOI:10.1021/acs.jmedchem.7b01406 |
| | Thalidomide-linker 13 Preparation Products And Raw materials |
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