H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2

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H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 Basic information
Product Name:H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2
Synonyms:THROMBIN RECEPTOR-LIKE 3 (1-6) AMIDE (MOUSE);PAR-4 (1-6) AMIDE (MOUSE);PAR-4 AGONIST AMIDE;PROTEINASE ACTIVATED RECEPTOR 4 (1-6) AMIDE (MOUSE);PROTEASE-ACTIVATED RECEPTOR-4 AGONIST AMIDE;PROTEASE ACTIVATED RECEPTOR 4 (PAR 4) (60-65) AMIDE [MUS MUSCULUS];COAGULATION FACTOR II RECEPTOR-LIKE 3 (1-6) AMIDE (MOUSE);H2N-GYPGKF-AMIDE
CAS:245443-52-1
MF:C33H46N8O7
MW:666.77
EINECS:
Product Categories:peptide
Mol File:245443-52-1.mol
H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 Structure
H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 Chemical Properties
Boiling point 1150.7±65.0 °C(Predicted)
density 1.300±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka9.84±0.15(Predicted)
color White to off-white
Water Solubility Water : 50 mg/mL (74.99 mM)
SequenceGly-Tyr-Pro-Gly-Lys-Phe-NH2
Safety Information
MSDS Information
H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 Usage And Synthesis
UsesProtease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).
IC 50PAR4
References[1] Moschonas IC, et al. Molecular requirements involving the human platelet protease-activated receptor-4 mechanism of activation by peptide analogues of its tethered-ligand. Platelets. 2017 Mar 7:1-10. doi: 10.1080/09537104.2017.1282607. [Epub ahead of print] DOI:10.1080/09537104.2017.1282607
[2] Huang SC, et al. Proteinase-activated receptor-1 (PAR1) and PAR2 mediate relaxation of guinea pig internal anal sphincter. Regul Pept. 2014 Feb 10;189:46-50. DOI:10.1016/j.regpep.2014.03.001
H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 Preparation Products And Raw materials
Tag:H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2(245443-52-1) Related Product Information
(Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human) Vkgils-NH2 Coagulation factor II receptor-like 2 (1-6) amide (human) Coagulation factor II receptor-like 2 (1-6) amide (mouse) PAR-4 (1-6) amide (human) H-Ser-Leu-Ile-Gly-Arg-Leu-NH2 H-Ser-Leu-Ile-Gly-Arg-Leu-OH H-Gly-Tyr-Pro-Gly-Gln-Val-OH H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2 H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 Ala-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt PROTEASE PROTEASE