- 2,6-Difluoronitrobenzene
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- $15.00 / 1KG
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2021-07-13
- CAS:19064-24-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2,6-Difluoronitrobenzene
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- $15.00 / 1KG
-
2021-07-10
- CAS:19064-24-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 2,6-Difluoronitrobenzene Basic information | | Uses |
| Product Name: | 2,6-Difluoronitrobenzene | | Synonyms: | 1,3-DIFLUORO-2-NITROBENZENE;2,6-DIFLUORONITROBENZENE;Benzene, 1,3-difluoro-2-nitro- (8CI,9CI);2,6-Difluoronitrobenzene 98%;2,6-Difluoronitrobenzene98%;2,6-Difluoronitroben;1,3-Difluoro-2-nitrobenzene2,6-difluoronitrobenzene;6-Difluoronitrobenzene | | CAS: | 19064-24-5 | | MF: | C6H3F2NO2 | | MW: | 159.09 | | EINECS: | 242-793-8 | | Product Categories: | HALIDE;Aromatic Hydrocarbons (substituted) & Derivatives;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks | | Mol File: | 19064-24-5.mol |  |
| | 2,6-Difluoronitrobenzene Chemical Properties |
| Melting point | 0C | | Boiling point | 91-92 °C/11 mmHg (lit.) | | density | 1.503 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.494(lit.) | | Fp | 190 °F | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to lump to clear liquid | | color | Light yellow to Yellow to Green | | Water Solubility | Slightly soluble in water. | | InChI | InChI=1S/C6H3F2NO2/c7-4-2-1-3-5(8)6(4)9(10)11/h1-3H | | InChIKey | SSNCMIDZGFCTST-UHFFFAOYSA-N | | SMILES | C1(F)=CC=CC(F)=C1[N+]([O-])=O | | CAS DataBase Reference | 19064-24-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 10-36/37/38 | | Safety Statements | 16-26-36-37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29049090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2,6-Difluoronitrobenzene Usage And Synthesis |
| Uses | 1,3-Difluoro-2-nitrobenzene is a useful chemical reagent. | | Chemical Properties | Light yellow to dark yellow solid | | Uses | 2,6-Difluoronitrobenzene may be used in the preparation of secondary amine precursors, required for the synthesis of two families of nitric oxide donors. | | General Description | 2,6-Difluoronitrobenzene is an organic building block. Molecular structure, conformation and potential to internal rotation of 2,6-difluoronitrobenzene been studied by gas-phase electron diffraction (GED), MP2 ab initio, and by B3LYP density functional calculations. | | Synthesis | Step 1: A mixture of sodium perborate tetrahydrate (65 g, 422 mmol) in glacial acetic acid (250 mL) was stirred at 80 °C. 2,6-Difluoroaniline (11.0 g, 85 mmol) was dissolved in glacial acetic acid (50 mL) and slowly added to the above mixture. The reaction temperature was maintained between 80-90°C for 1 hour. The cooled reaction mixture was poured into water and extracted twice with ether. The organic layers were combined, washed with dilute sodium bicarbonate solution, dried over anhydrous magnesium sulfate and the solvent evaporated. The residue was purified by a Biotage fast chromatography system (FlasH90i, silica gel column, 10% THF/hexane as eluent) and the product was washed with hexane to give 2,6-difluoronitrobenzene (7.0 g, 52% yield). Mass spectrum (ESI) m/z 160 ([M + H]+). | | References | [1] Patent: US2005/222148, 2005, A1. Location in patent: Page/Page column 58
[2] Patent: US2008/153873, 2008, A1. Location in patent: Page/Page column 20
[3] Journal of Organic Chemistry, 1992, vol. 57, # 21, p. 5577 - 5585
[4] European Journal of Organic Chemistry, 2006, # 5, p. 1109 - 1112
[5] Patent: US2006/9509, 2006, A1. Location in patent: Page/Page column 8 |
| | 2,6-Difluoronitrobenzene Preparation Products And Raw materials |
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