- 2,6-Difluoroaniline
-
- $0.00 / 200KG
-
2026-01-26
- CAS:5509-65-9
- Min. Order: 1000KG
- Purity: 99
- Supply Ability: 20000
- 2,6-Difluoroaniline
-
- $0.00 / 25KG
-
2026-01-05
- CAS:5509-65-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- 2,6-Difluoroaniline
-
- $0.00 / 25KG
-
2025-12-01
- CAS:5509-65-9
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 10000KGS
|
| | 2,6-Difluoroaniline Basic information |
| Product Name: | 2,6-Difluoroaniline | | Synonyms: | Benzenamine, 2,6-difluoro-;2,6-DIFLUOROANILINE;2,6-DIFLUOROBENZENAMINE;2,6-DIFLUOROANILINE, 97+%;2,6-Difluoroaniline,98%;2,6-Difluoroaniline,min.97%;2,6-Difluoroaniline 98%;2,6-Difluoroaniline, min. 97% | | CAS: | 5509-65-9 | | MF: | C6H5F2N | | MW: | 129.11 | | EINECS: | 226-853-0 | | Product Categories: | Anilines, Aromatic Amines and Nitro Compounds;Fluorobenzene;Miscellaneous;Fluorobenzene Series;Amines;C2 to C6;Nitrogen Compounds;bc0001 | | Mol File: | 5509-65-9.mol |  |
| | 2,6-Difluoroaniline Chemical Properties |
| Boiling point | 51-52 °C/15 mmHg (lit.) | | density | 1.199 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.508(lit.) | | Fp | 110 °F | | storage temp. | Keep in dark place,Sealed in dry,2-8°C | | solubility | Chloroform, Ethyl Acetate (Slightly) | | form | Liquid | | pka | 1.81±0.10(Predicted) | | color | Clear yellow to brown | | Specific Gravity | 1.28 | | Water Solubility | Slightly soluble in water. | | BRN | 2802697 | | Stability: | Hygroscopic | | InChI | 1S/C6H5F2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H2 | | InChIKey | ODUZJBKKYBQIBX-UHFFFAOYSA-N | | SMILES | Nc1c(F)cccc1F | | CAS DataBase Reference | 5509-65-9(CAS DataBase Reference) | | NIST Chemistry Reference | 2,6-Difluoroaniline(5509-65-9) | | EPA Substance Registry System | 2,6-Difluoroaniline (5509-65-9) |
| | 2,6-Difluoroaniline Usage And Synthesis |
| Chemical Properties | clear yellow to brown liquid | | Uses | 2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide. | | Uses | 2,6-Difluoroaniline was used in the synthesis of:
- N-2,6-difluorophenyl-5-methoxy-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide, herbicidal compound
- series of 2,6,9-trisubstituted purine inhibitors of p38α kinase
- substituted phenylthiomorpholine dioxide, an active pharmaceutical intermediate
| | Uses | 2,6-Difluoroaniline and several related primary amines are oxidized in chloroform by peroxybenzoic acid to the corresponding nitroso compounds. For example, treatment of 2,6-difluoroaniline with sodium azide can obtain 4-fluoro-2,1,3-benzoxadiazole, and the product is nitrified to obtain 7-nitro derivatives[1]. 2,6-Difluoroaniline is an important raw material and intermediate in organic synthesis, medicine, pesticides, dyes and other fields. | | Toxics Screening Level | The initial threshold screening level (ITSL) for 2,6-difluoroaniline (DFA) is 2.0 μg/m3 based on an annual averaging time. | | References | [1] Nunno L, et al. Oxidation of substituted anilines to nitroso-compounds. J. Chem. Soc. C, 1970; 9: 1433-1434. |
| | 2,6-Difluoroaniline Preparation Products And Raw materials |
| Raw materials | 2,6-Difluorobenzamide | | Preparation Products | DBD-PZ-->4-(N,N-DIMETHYLAMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE-->Abemaciclib-->4-(CHLOROSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE-->N1-(2,6-DIFLUORO-3-NITROPHENYL)ACETAMIDE-->4-Amino-2,6-difluorophenol-->4-FLUORO-2,1,3-BENZOXADIAZOLE-->4-Bromo-2,6-difluoroaniline-->2,6-Difluoro-4-nitrophenol-->2,6-DIFLUORO-4-NITROANILINE-->4-Fluoro-7-nitrobenzofurazan-->2,6-Difluoronitrobenzene-->2,6-Difluorophenol-->ETHYL 2-(2,6-DIFLUOROANILINO)-2-OXOACETATE-->5-Chloro-N-(2,6-difluorophenyl)pyrazine-2-carboxamide-->Benzenamine, 2,6-difluoro-N-(2-methylpropyl)--->1-Bromo-2,6-difluorobenzene |
|