Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Hydroxymethylmorpholine

2-Hydroxymethylmorpholine

2-Hydroxymethylmorpholine Structure
2-Hydroxymethylmorpholine structure
CAS No.
103003-01-6
Chemical Name:
2-Hydroxymethylmorpholine
Synonyms
2-MORPHOLINEMETHANOL;2-Morpholinylmethanol;MORPHOLIN-2-YL-METHANOL;-Hydroxymethylmorpholine;2-HYDROXYMETHYLMORPHOLINE;Morpholin-2-ylMethanol-HCl;2-HYDROXYMETHYLMORPHOLINE 95%
CBNumber:
CB0264099
Molecular Formula:
C5H11NO2
Molecular Weight:
117.15
MDL Number:
MFCD03426271
MOL File:
103003-01-6.mol
MSDS File:
SDS
Last updated:2026-05-27 17:39:44
Request For Quotation

2-Hydroxymethylmorpholine Properties

Boiling point 220.1±15.0 °C(Predicted)
Density 1.045±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 14.36±0.10(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P280-P301+P312-P362+P364
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  2934999090

2-Hydroxymethylmorpholine price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR315521 Morpholin-2-ylmethanol 99% 103003-01-6 1g $123 2026-06-04 Buy
Apolloscientific OR315521 Morpholin-2-ylmethanol 99% 103003-01-6 5g $573 2026-06-04 Buy
Matrix Scientific 073626 Morpholin-2-ylmethanol 103003-01-6 1.00g $125 2026-05-18 Buy
Matrix Scientific 073626 Morpholin-2-ylmethanol 103003-01-6 5.00g $438 2026-05-18 Buy
Matrix Scientific 073626 Morpholin-2-ylmethanol 103003-01-6 25.00g $1534 2026-05-18 Buy
Product number Packaging Price Buy
OR315521 1g $123 Buy
OR315521 5g $573 Buy
073626 1.00g $125 Buy
073626 5.00g $438 Buy
073626 25.00g $1534 Buy

2-Hydroxymethylmorpholine Chemical Properties,Uses,Production

Uses

2-Hydroxymethylmorpholine is used to study structure-activity relationship in two series of aminoalkyl substituted coumarin inhibitors of gyrase B.

Synthesis

4-BOC-2-MORPHOLINECARBOXYLIC ACID

189321-66-2

2-Hydroxymethylmorpholine

103003-01-6

The general procedure for the synthesis of 2-hydroxymethylmorpholine from 4-Boc-2-morpholinecarboxylic acid was as follows: to a solution of N-Boc-2-morpholinecarboxylic acid (2 g) in tetrahydrofuran (THF, 5 mL) was slowly added a borane-THF complex (1N, 10.38 eq.) at 0 °C. The reaction mixture was stirred at 0 °C for 30 min, then brought to room temperature and continued stirring for 2 hours. Upon completion of the reaction, the reaction was quenched by careful addition of water (200 mL) and then extracted with dichloromethane (CH2Cl2). The organic phase was dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give 490 mg of the crude product (26% yield). Finally, the crude product was dissolved in 4N hydrochloric acid/dioxolane solution with stirring to give the amine salt of 2-hydroxymethylmorpholine.

References

[1] Patent: WO2004/33440, 2004, A1. Location in patent: Page 173

2-Hydroxymethylmorpholine Preparation Products And Raw materials

Raw materials

4-Boc-2-morpholinecarboxylic acid Tetrahydrofuran Borane-tetrahydrofuran complex

Preparation Products

2-Hydroxymethyl-4-Boc-morpholine 4-Cbz-2-hydroxymethylmorpholine

2-Hydroxymethylmorpholine Suppliers

Global( 103)Suppliers
Supplier Tel Email Country ProdList Advantage
ForeChem (Nantong) Technology Co.,Ltd. 513-85982855 18921614129 sales@xianxingpharm.com China 2712 61
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7882 64
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Suzhou Sibian Chemical Technology Co.,Ltd. 0512-65617459 18915409046 sales@sibian-chem.com China 1917 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9513 58
Shanghai Sheepchem Co., Ltd. +86 (21) 6715-7650 sheepchem@163.com China 993 60
Supplier Advantage
ForeChem (Nantong) Technology Co.,Ltd. 61
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Tetranov Biopharm 64
Adamas Reagent, Ltd. 59
Shanghai Ennopharm Co., Ltd. 65
Hangzhou Sage Chemical Co., Ltd. 58
Suzhou Sibian Chemical Technology Co.,Ltd. 55
Shanghai Topbiochem Technology Co., Ltd 58
Shanghai Sheepchem Co., Ltd. 60

View Lastest Price from 2-Hydroxymethylmorpholine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Hydroxymethylmorpholine pictures 2019-12-23 2-Hydroxymethylmorpholine
103003-01-6
 $1.00 1KG 99% 100KG Career Henan Chemical Co

2-Hydroxymethylmorpholine Spectrum

2-Hydroxymethylmorpholine(103003-01-6)1HNMR

103003-01-6(2-Hydroxymethylmorpholine)Related Search:

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Indeloxazine Indeloxazine hydrochloride Teniloxazine Reboxetine mesylate
viloxazine Nafoxadol (S)-2-Hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester,(S)-N-BOC-2-HYDROXYMETHYLMORPHOLINE (R )-2-Hydroxymethylmorpholine (R)-4-Boc-3-hydroxymethylmorpholine
(R)-N-Boc-2-Hydroxymethylmorpholine 2-Hydroxymethyl-4-Boc-morpholine (R)-4-BENZYL-3-HYDROXYMETHYLMORPHOLINE 3(R)-Hydroxymethylmorpholine 4-Boc-2-morpholinecarboxylic acid
3(S)-Hydroxymethylmorpholine 4-Benzyl-3-hydroxymethylmorpholine Fmoc-cop

1of4

MORPHOLIN-2-YL-METHANOL 2-HYDROXYMETHYLMORPHOLINE 95% Morpholin-2-ylMethanol-HCl 2-HYDROXYMETHYLMORPHOLINE 2-MORPHOLINEMETHANOL -Hydroxymethylmorpholine 2-Morpholinylmethanol 103003-01-6 pharmacetical