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2-Hydroxymethylmorpholine

2-Hydroxymethylmorpholine Structure
2-Hydroxymethylmorpholine structure
CAS No.
103003-01-6
Chemical Name:
2-Hydroxymethylmorpholine
Synonyms
2-MORPHOLINEMETHANOL;2-Morpholinylmethanol;MORPHOLIN-2-YL-METHANOL;-Hydroxymethylmorpholine;2-HYDROXYMETHYLMORPHOLINE;Morpholin-2-ylMethanol-HCl;2-HYDROXYMETHYLMORPHOLINE 95%
CBNumber:
CB0264099
Molecular Formula:
C5H11NO2
Molecular Weight:
117.15
MDL Number:
MFCD03426271
MOL File:
103003-01-6.mol
Last updated:2025-07-24 18:13:40
Product description Number Pack Size Price
2-Hydroxymethylmorpholine H972975 50mg $45
2-Hydroxymethylmorpholine X8636 100mg $120
Morpholin-2-ylmethanol 95+% 073626 250mg $163
2-Hydroxymethylmorpholine X8636 1g $320
Morpholin-2-ylmethanol 95+% 073626 1g $395
Request For Quotation

2-Hydroxymethylmorpholine Properties

Boiling point 220.1±15.0 °C(Predicted)
Density 1.045±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 14.36±0.10(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P280-P301+P312-P362+P364
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  2934999090

2-Hydroxymethylmorpholine price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H972975 2-Hydroxymethylmorpholine 103003-01-6 50mg $45 2021-12-16 Buy
AK Scientific X8636 2-Hydroxymethylmorpholine 103003-01-6 100mg $120 2021-12-16 Buy
Matrix Scientific 073626 Morpholin-2-ylmethanol 95+% 103003-01-6 250mg $163 2021-12-16 Buy
AK Scientific X8636 2-Hydroxymethylmorpholine 103003-01-6 1g $320 2021-12-16 Buy
Matrix Scientific 073626 Morpholin-2-ylmethanol 95+% 103003-01-6 1g $395 2021-12-16 Buy
Product number Packaging Price Buy
H972975 50mg $45 Buy
X8636 100mg $120 Buy
073626 250mg $163 Buy
X8636 1g $320 Buy
073626 1g $395 Buy

2-Hydroxymethylmorpholine Chemical Properties,Uses,Production

Uses

2-Hydroxymethylmorpholine is used to study structure-activity relationship in two series of aminoalkyl substituted coumarin inhibitors of gyrase B.

Synthesis

4-BOC-2-MORPHOLINECARBOXYLIC ACID

189321-66-2

2-Hydroxymethylmorpholine

103003-01-6

The general procedure for the synthesis of 2-hydroxymethylmorpholine from 4-Boc-2-morpholinecarboxylic acid was as follows: to a solution of N-Boc-2-morpholinecarboxylic acid (2 g) in tetrahydrofuran (THF, 5 mL) was slowly added a borane-THF complex (1N, 10.38 eq.) at 0 °C. The reaction mixture was stirred at 0 °C for 30 min, then brought to room temperature and continued stirring for 2 hours. Upon completion of the reaction, the reaction was quenched by careful addition of water (200 mL) and then extracted with dichloromethane (CH2Cl2). The organic phase was dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give 490 mg of the crude product (26% yield). Finally, the crude product was dissolved in 4N hydrochloric acid/dioxolane solution with stirring to give the amine salt of 2-hydroxymethylmorpholine.

References

[1] Patent: WO2004/33440, 2004, A1. Location in patent: Page 173

2-Hydroxymethylmorpholine Preparation Products And Raw materials

Raw materials

4-BOC-2-MORPHOLINECARBOXYLIC ACID Tetrahydrofuran Borane-tetrahydrofuran complex

Preparation Products

2-HYDROXYMETHYL-4-BOC-MORPHOLINE 4-CBZ-2-HYDROXYMETHYLMORPHOLINE

2-Hydroxymethylmorpholine Suppliers

Global( 108)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 9983 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14343 58
Unipharm pharmaceutical industry Co., Ltd 		536-8266195 +8613953676784 lee@unipharm-sd.com China 1202 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Fuxin Pharmaceutical 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Win-Win chemical CO., Limited 		58
Unipharm pharmaceutical industry Co., Ltd 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Nextpeptide Inc 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
PT CHEM GROUP LIMITED 		58

View Lastest Price from 2-Hydroxymethylmorpholine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Hydroxymethylmorpholine pictures 2019-12-23 2-Hydroxymethylmorpholine
103003-01-6
 US $1.00 / KG 1KG 99% 100KG Career Henan Chemical Co

2-Hydroxymethylmorpholine Spectrum

2-Hydroxymethylmorpholine(103003-01-6)1HNMR

103003-01-6(2-Hydroxymethylmorpholine)Related Search:

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MORPHOLIN-2-YL-METHANOL 2-HYDROXYMETHYLMORPHOLINE 95% Morpholin-2-ylMethanol-HCl 2-HYDROXYMETHYLMORPHOLINE 2-MORPHOLINEMETHANOL -Hydroxymethylmorpholine 2-Morpholinylmethanol 103003-01-6 pharmacetical