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BOC-L-Serine

CAS No.
3262-72-4
Chemical Name:
BOC-L-Serine
Synonyms
Boc-Ser.H2O;Boc-Ser;BOC-L-SER;N-BOC-L-SERINE;BOC-L-SER-OH;221-867-3;BOC-SERINE;(R)-2-((tert-butoxycarbonyl)aMino)-3-hydroxypropanoic acid;BOC-L-SERINE;Boc-D-Ser.H2o
CBNumber:
CB0668033
Molecular Formula:
C8H15NO5
Molecular Weight:
205.21
MDL Number:
MFCD00037243
MOL File:
3262-72-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:48
Product description Number Pack Size Price
Boc-Ser-OH ≥99.0% (T) 15500 5g $38.9
Boc-Ser-OH Novabiochem? 8.53020 25G $126
Boc-Ser-OH ≥99.0% (T) 15500 25g $101
Boc-Ser-OH Novabiochem? 8.53020 100G $386
N-(tert-Butoxycarbonyl)-L-serine >97.0%(T) B1637 5g $28
More product size

BOC-L-Serine Properties

Melting point 91 °C (dec.)(lit.)
alpha -7.5 º (c=2, water)
Boiling point 385.1±37.0 °C(Predicted)
Density 1.240±0.06 g/cm3(Predicted)
refractive index -4 ° (C=1, AcOH)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 3.62±0.10(Predicted)
form Powder
color White
optical activity [α]20/D 3.5±0.5°, c = 2% in acetic acid
Water Solubility almost transparency
BRN 2212252
Major Application peptide synthesis
InChI 1S/C8H15NO5/c1-8(2,3)14-7(13)9-5(4-10)6(11)12/h5,10H,4H2,1-3H3,(H,9,13)(H,11,12)/t5-/m0/s1
InChIKey FHOAKXBXYSJBGX-YFKPBYRVSA-N
SMILES CC(C)(C)OC(=O)N[C@@H](CO)C(O)=O
CAS DataBase Reference 3262-72-4(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P261-P271-P280
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HS Code  29241990
Storage Class 11 - Combustible Solids
NFPA 704
0
1 0

BOC-L-Serine price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 15500 Boc-Ser-OH ≥99.0% (T) 3262-72-4 5g $38.9 2026-03-19 Buy
Sigma-Aldrich 8.53020 Boc-Ser-OH Novabiochem? 3262-72-4 25G $126 2026-03-19 Buy
Sigma-Aldrich 15500 Boc-Ser-OH ≥99.0% (T) 3262-72-4 25g $101 2026-03-19 Buy
Sigma-Aldrich 8.53020 Boc-Ser-OH Novabiochem? 3262-72-4 100G $386 2025-07-31 Buy
TCI Chemical B1637 N-(tert-Butoxycarbonyl)-L-serine >97.0%(T) 3262-72-4 5g $28 2026-03-19 Buy
Product number Packaging Price Buy
15500 5g $38.9 Buy
8.53020 25G $126 Buy
15500 25g $101 Buy
8.53020 100G $386 Buy
B1637 5g $28 Buy

BOC-L-Serine Chemical Properties,Uses,Production

Chemical Properties

white to light brown powder

Uses

Starting material for the synthesis of various a-amino acids via the b-lactone

Uses

Boc-Ser-OH may be used in the synthesis of the following:

  • 2-(N-Fmoc)-3-(N-Boc-N-methoxy)-diaminopropanoic acid (Fmoc: 9-fluorenylmethoxycarbonyl; Boc: t-butyloxycarbonyl)
  • Boc-Ser-Leu-OMe
  • cyclic peptide synthesis
  • benzylsulfonyl-D-Ser-Ser-4-amidinobenzylamide

General Description

Boc-Ser-OH is an amino acid derivative.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

18.1g of L-serine, was added to 200m1 of 0.010mol/L sodium carbonate solution and dissolved with stirring, then 8g of (BoC)0 was added and reacted for 3 hours, then 8g of (BoC)0 was added and reacted for 5 hours, and finally 9g of (Boc)0 was added and reacted for 7 hours. The impurities were extracted three times with petroleum ether 10 ml/time. 3 mol/L hydrochloric acid was used to adjust the pH=3 and then the product was extracted three times with tetrahydrofuran 0.5 L/time. The ester layers were combined and washed with brine to neutral. Add 15 g of anhydrous sodium sulfate and dry for 8 hours. Filtration, filtrate concentrated dry under reduced pressure, add 50ml petroleum squint stirring crystallization. Centrifuge the product and dry. BOC-L-serine 23.1 g was obtained. yield 90.15%.

Global( 458)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 4000 58
Capot Chemical Co.,Ltd.
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Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
Sichuan Jiaying Lai Technology Co.,LTD
18716376478 ycling@enlaibio.com CHINA 302 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58

View Lastest Price from BOC-L-Serine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BOC-L-Serine pictures 2026-04-29 BOC-L-Serine
3262-72-4
US $0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
BOC-L-Serine pictures 2026-03-20 BOC-L-Serine
3262-72-4
US $10.00 / KG 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd
BOC-L-Serine pictures 2024-07-11 BOC-L-Serine
3262-72-4
US $1.00 / KG 1KG 98% 20T Shaanxi Dideu Medichem Co. Ltd
  • BOC-L-Serine pictures
  • BOC-L-Serine
    3262-72-4
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • BOC-L-Serine pictures
  • BOC-L-Serine
    3262-72-4
  • US $10.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • BOC-L-Serine pictures
  • BOC-L-Serine
    3262-72-4
  • US $1.00 / KG
  • 98%
  • Shaanxi Dideu Medichem Co. Ltd
L-Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI) Boc-Ser-OH Synonyms:Boc-L-serine N-ALPHA-T-BUTYLOXYCARBONYL-L-SERINE BOC-L-PROLINOL LIQUID N-[(1,1-DIMETHYLETHOXY)CARBONYL]- L-SERINE N-Boc-L-serine, 98%(dry wt.), may cont. up to 10% water BOC-L-SERINE extrapure N-(tert-Butoxycarbonyl)-L-serine, Boc-L-serine (2R)-3-Hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid L-Serine, N-[(1,1-dimethylethoxy)carbonyl]- BOC-L-SERINE, TECH., HYDRATE, 93% N-T-BOC-L-SERINE CRYSTALLINE N-Boc-L-serine Boc-Ser-OH 2-(tert-butoxycarbonyl)-3-hydroxypropanoic acid L-Serine-d3-N-t-BOC Boc-L-serine, 99%, anhydrous Boc-Ser.H2O (R)-2-((tert-butoxycarbonyl)aMino)-3-hydroxypropanoic acid Boc-D-Ser.H2o N-Boc-L-Serine, 95+% (R)-2-amino-3-(2-aminoethylamino)-1-propanol trihydrochloride Boc-Ser-OH >=99.0% (T) (Tert-Butoxy)Carbonyl Ser-OH (ee>99.4%, H2O <0.5%) (S)-N-BOC-SERINE (S)-Boc-2-amino-3-hydroxypropionic acid Boc-L-serine≥ 98% (HPLC) Boc-L-β-Hydroxyalanine N-Boc-L-serine,99%e.e. N-Boc-L-serine(contains ca. 10% H2O) Boc-Ser BOC-L-Serine hydrate, tech. (S)-2-[(tert-Butyloxycarbonyl)amino]-3-hydroxypropionic acid N-(tert-Butoxycarbonyl)serine N-(tert-Butyloxycarbonyl)-L-serine N-[(tert-Butyloxy)carbonyl]-L-serine (2S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid Boc-Ser-OH·H2O Boc-L-Serine Monohydrate BOC-L-Serine hydrate,93%,tech. N-BOC-L-SERINE N-ALPHA-T-BOC-L-SERINE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-SERINE N-T-BUTOXYCARBONYL-L-SERINE N-(TERT-BUTOXYCARBONYL)-L-SERINE BOC-SERINE-OH BOC-SERINE BOC-L-SER-OH BOC-L-SER BOC-L-SERINE (2S)-3-hydroxy-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoate N-(tert-Butoxycarbonyl)-L-serine > 221-867-3 (2S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid N-tert-Boc-L-serine N-Boc-L-serine, 98% Boc-Ser-OH 98% 3262-72-4 C8H15NO5 HOCH2CHCOOHNHCOOCCH33