(Methoxymethyl)triphenylphosphonium chloride
- CAS No.
- 4009-98-7
- Chemical Name:
- (Methoxymethyl)triphenylphosphonium chloride
- Synonyms
- MMC;MTPPC;DOMIT-012;AURORA KA-1153;(MethoxymethyL;phosphonium chL;Methoxymethyl triphe;METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-;Triphenyl(methoxymethyl)phosphonium;methoxymethyl(triphenyl)phosphanium
- CBNumber:
- CB3455456
- Molecular Formula:
- C20H20ClOP
- Molecular Weight:
- 342.8
- MDL Number:
- MFCD00011800
- MOL File:
- 4009-98-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 185-195 °C (dec.)(lit.) |
|---|---|
| bulk density | 450-500kg/m3 |
| vapor pressure | <1 hPa ( 20 °C) |
| Flash point | >250°C |
| storage temp. | Store below +30°C. |
| solubility | >1100g/l soluble,(decomposition) |
| form | Crystalline Powder |
| color | White to almost white |
| PH | 2.2 (1100g/l, H2O, 20℃) |
| Water Solubility | decomposes |
| Sensitive | Hygroscopic |
| BRN | 924215 |
| InChI | 1S/C20H20OP.ClH/c1-21-17-22(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1 |
| InChIKey | SJFNDMHZXCUXSA-UHFFFAOYSA-M |
| SMILES | [Cl-].COC[P+](c1ccccc1)(c2ccccc2)c3ccccc3 |
| LogP | -1.17 |
| CAS DataBase Reference | 4009-98-7(CAS DataBase Reference) |
| UNSPSC Code | 12352107 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H411 | |||||||||
| Precautionary statements | P264-P270-P273-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| RIDADR | UN 1390 4.3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 29310095 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 Eye Irrit. 2 Skin Irrit. 2 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
(Methoxymethyl)triphenylphosphonium chloride price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 309567 | (Methoxymethyl)triphenylphosphonium chloride 97% | 4009-98-7 | 25g | $69.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.18580 | Methoxymethyl-triphenylphosphonium chloride for synthesis | 4009-98-7 | 50G | $110 | 2026-04-30 | Buy |
| Sigma-Aldrich | 309567 | (Methoxymethyl)triphenylphosphonium chloride 97% | 4009-98-7 | 100g | $144 | 2026-04-30 | Buy |
| TCI Chemical | M0828 | (Methoxymethyl)triphenylphosphonium Chloride >99.0%(HPLC) | 4009-98-7 | 25g | $24 | 2026-04-30 | Buy |
| TCI Chemical | M0828 | (Methoxymethyl)triphenylphosphonium Chloride >99.0%(HPLC) | 4009-98-7 | 100g | $68 | 2026-04-30 | Buy |
(Methoxymethyl)triphenylphosphonium chloride Chemical Properties, Uses, Production
Chemical Properties
WHITE TO ALMOST WHITE FINE CRYSTALLINE POWDER
Uses
PTC catalyst
Uses
(Methoxymethyl)triphenylphosphonium chloride is used as a phase transfer catalyst and in the synthesis of taxol-A fragment. It is widely used in the synthesis of pharmaceutical product cephalotaxine, which is used as an antiviral and antitumor agent.
Uses
Intermediates of Liquid Crystals
reaction suitability
reaction type: C-C Bond Formation
Synthesis
107-30-2
603-35-0
4009-98-7
The general procedure for the synthesis of (methoxymethyl)triphenylphosphonium chloride from chloromethyl methyl ether and triphenylphosphine was as follows: 20.0 g of triphenylphosphine was placed in a round-bottomed flask, dissolved in an appropriate amount of toluene, and heated to 95°C. The reaction was carried out at a constant temperature for 16 hours. Subsequently, 6.37 mL of chloromethyl methyl ether was slowly added dropwise and the reaction was kept at temperature for 16 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature and the solid product was collected by filtration. The filter cake was washed three times with toluene to remove impurities and then dried to give 25.4 g of white phosphonium salt in 97.3% yield.
References
[1] Synthesis (Germany), 2013, vol. 45, # 5, p. 596 - 600
[2] Patent: CN107936009, 2018, A. Location in patent: Paragraph 0042; 0087-0088
[3] Bulletin of the Chemical Society of Japan, 1980, vol. 53, # 12, p. 3436 - 3438
[4] Patent: CN106588982, 2017, A. Location in patent: Paragraph 0008; 0017; 0018; 0019; 0020; 0021; 0022-0025
[5] Journal of the American Chemical Society, 1976, vol. 98, p. 6613 - 6623
(Methoxymethyl)triphenylphosphonium chloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Yihua Biotechnology Co., Ltd | 13429882898; 13429882898 | 1096323105@qq.com | China | 291 | 58 |
| Shouguang Jiasheng Chemical Co., Ltd. | 0536-7971999 13583611556 | sgjiasheng@hotmail.com | China | 300 | 58 |
| Nanjing Dilu Pharmaceutical Co., Ltd | 18014482516 18014482516 | 977144864@qq.com | China | 424 | 58 |
| Hebei Han'en New Material Technology Co., Ltd | 18032751346 | 2929218726@qq.com | China | 27 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
View Latest Price from (Methoxymethyl)triphenylphosphonium chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-20 | (Methoxymethyl)triphenylphosphonium chloride
4009-98-7
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-02 | (Methoxymethyl)triphenylphosphonium chloride
4009-98-7
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-03-20 | (Methoxymethyl)triphenylphosphonium chloride
4009-98-7
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- (Methoxymethyl)triphenylphosphonium chloride
4009-98-7
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- (Methoxymethyl)triphenylphosphonium chloride
4009-98-7
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- (Methoxymethyl)triphenylphosphonium chloride
4009-98-7
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
