Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Bromo-5-iodopyridine

2-Bromo-5-iodopyridine

2-Bromo-5-iodopyridine Structure
2-Bromo-5-iodopyridine structure
CAS No.
73290-22-9
Chemical Name:
2-Bromo-5-iodopyridine
Synonyms
2-BROMO-5-IODOPYRIDINE;2-Bromo-5-Iodine Pyridine;Pyridine, 2-bromo-5-iodo-;2-Bromo-5-iodopyridine 96%;2-Bromo-5-iodopyridine,97%;2-Bromo-5-iodopyridine >JR-6787, 2-Bromo-5-iodopyridine, 97%;2-Bromo-5-iodopyridine ISO 9001：2015 REACH
CBNumber:
CB0338941
Molecular Formula:
C5H3BrIN
Molecular Weight:
283.89
MDL Number:
MFCD03095201
MOL File:
73290-22-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:40:59
Request For Quotation

2-Bromo-5-iodopyridine Properties

Melting point 121-123 °C (lit.)
Boiling point 278.6±20.0 °C(Predicted)
Density 2.347±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka -1.23±0.10(Predicted)
form Powder
color White to off-white
Sensitive Light Sensitive
BRN 109100
InChI InChI=1S/C5H3BrIN/c6-5-2-1-4(7)3-8-5/h1-3H
InChIKey LLKRSJVPTKFSLS-UHFFFAOYSA-N
SMILES C1(Br)=NC=C(I)C=C1
CAS DataBase Reference 73290-22-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-37/38-41
Safety Statements  26-36/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2-Bromo-5-iodopyridine price More Price(83)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 652598 2-Bromo-5-iodopyridine 96% 73290-22-9 5g $110 2026-04-30 Buy
Sigma-Aldrich 652598 2-Bromo-5-iodopyridine 96% 73290-22-9 25g $167 2026-04-30 Buy
TCI Chemical B3765 2-Bromo-5-iodopyridine >97.0%(GC) 73290-22-9 5g $26 2026-04-30 Buy
TCI Chemical B3765 2-Bromo-5-iodopyridine >97.0%(GC) 73290-22-9 25g $78 2026-04-30 Buy
AstaTech 54629 2-BROMO-5-IODOPYRIDINE 95% 73290-22-9 25G $30 2026-04-30 Buy
Product number Packaging Price Buy
652598 5g $110 Buy
652598 25g $167 Buy
B3765 5g $26 Buy
B3765 25g $78 Buy
54629 25G $30 Buy

2-Bromo-5-iodopyridine Chemical Properties, Uses, Production

Chemical Properties

White crystalline

Uses

2-Bromo-5-iodopyridine can be used to develop fluorescent compounds (manisyl-substituted terpyridine, bipyridine, and phenanthroline). It is also a useful reagent for investigating the structure/activity relationships of non-nucleoside adenosine kinase inhibitors.

Synthesis

2-Amino-5-iodopyridine

20511-12-0

2-Bromo-5-iodopyridine

73290-22-9

General procedure for the synthesis of 2-bromo-5-iodopyridine from 2-amino-5-iodopyridine: Bromine (3 mL) was slowly added dropwise to a mixture of 2-amino-5-iodopyridine (5 g, 20 mmol) dissolved in 48% aqueous hydrobromic acid (10 mL), and the reaction system was cooled by an ice bath to maintain the reaction at low temperature. Subsequently, sodium nitrite (3.4 g, dissolved in 5 mL of water) solution was added dropwise, and the reaction temperature was controlled not to exceed 15 °C. After the dropwise addition, a solution of sodium hydroxide (16 g) in water (40 mL) was added. A brown solid precipitated from the reaction mixture and was extracted with dichloromethane (50 mL). The organic phases were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to afford the target product 2-bromo-5-iodopyridine (4.4 g, 78% yield).

References

[1] Journal of Heterocyclic Chemistry, 2017, vol. 54, # 5, p. 2656 - 2663
[2] Journal of Organic Chemistry, 2009, vol. 74, # 15, p. 5228 - 5236
[3] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 3, p. 467 - 479
[4] Patent: WO2005/92304, 2005, A2. Location in patent: Page/Page column 42
[5] Tetrahedron, 2002, vol. 58, # 14, p. 2885 - 2890

2-Bromo-5-iodopyridine synthesis

223463-14-7
73290-22-9
Synthesis of 2-Bromo-5-iodopyridine from 2-Bromopyridine-5-boronic acid

2-Bromo-5-iodopyridine Preparation Products And Raw materials

Raw materials

1,2-Diiodoethane Tetrahydrofuran 2,5-Dibromopyridine n-Butyllithium 5-Bromo-2-iodopyridine
2,5-Diiodopyridine 2-Bromopyridine-5-boronic acid 2-Amino-5-iodopyridine 5-Amino-2-bromopyridine 2-Aminopyridine

1of2

Preparation Products

2-Bromo-4-iodopyridine 2-Bromo-5-ethynylpyridine

2-Bromo-5-iodopyridine Suppliers

Global Suppliers ( 387)
Supplier Tel Email Country ProdList Advantage
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 6065 65
Nantong fangran Pharmaceutical Technology Co., Ltd 18795720669 17751318538 lance@decentpharma.cn China 63 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Liaoning Tianhua Chemical Co., Ltd. 0418-6530555 2855550 China 338 69
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Shanghai Qiao Chemical Science Co., Ltd 65
Nantong fangran Pharmaceutical Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Liaoning Tianhua Chemical Co., Ltd. 69
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61

View Latest Price from 2-Bromo-5-iodopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-5-iodopyridine pictures 2026-09-18 2-Bromo-5-iodopyridine
73290-22-9
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2-Bromo-5-iodopyridine pictures 2026-09-02 2-Bromo-5-iodopyridine
73290-22-9
 $1.00-200.00 1KG 99%, 99.5% Sublimated Henan Fengda Chemical Co., Ltd
2-Bromo-5-iodopyridine pictures 2026-08-20 2-Bromo-5-iodopyridine
73290-22-9
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited

2-Bromo-5-iodopyridine Spectrum

2-Bromo-5-iodopyridine(73290-22-9)1HNMR

73290-22-9 (2-Bromo-5-iodopyridine) Related Search:

3-Bromoanisole 2-Bromo-5-chloropyridine 2,6-Lutidine 2-Bromo-5-fluoropyridine 1-Hexadecylpyridinium bromide
2-Bromopyridine 2-Hydroxypyridine Sulfasalazine Chromium picolinate 2-Bromo-5-iodobenzonitrile
Bromine 2-Bromo-5-iodo-3-methylpyridine 3-Bromo-5-iodo-pyridin-4-ylamine 2-Bromo-3,5-diiodopyridine 4-Bromo-2-iodopyridine
2-Bromo-5-iodo-4-methylpyridine 3-BROMO-2-IODOPYRIDINE 3-Bromo-5-iodo-pyridine

1of4

2-Bromo-5-iodopyridine,97% 2-Bromo-5-iodopyridine 96% 2-BROMO-5-IODOPYRIDINE JR-6787, 2-Bromo-5-iodopyridine, 97% 2-Bromo-5-iodopyridine > Pyridine, 2-bromo-5-iodo- 2-Bromo-5-iodopyridine ISO 9001：2015 REACH 2-Bromo-5-Iodine Pyridine 73290-22-9 205511-12-0 Heterocyclic Building Blocks Halogenated Heterocycles Pyridines Building Blocks Heterocycle-Pyridine series Pyridine Series Heterocyclic Building Blocks Propidium heterocyclic series Boronic Acid C5Heterocyclic Building Blocks Halogenated Heterocycles Pyridine Halides Pyridines Heterocycle