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| | LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Basic information |
| Product Name: | LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) | | Synonyms: | 2,5-dihydroxy-l-tyrosine;4,5-trihydroxyphenyl)-3-(l-alanin;6-oh-dopa;l-2,4,5-trihydroxyphenylalanine;l-6-hydroxydopa;3-(3,4,6-Tirhydroxyphenyl)-alanine;(2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid;l-hydroxydopa | | CAS: | 27244-64-0 | | MF: | C9H11NO5 | | MW: | 213.19 | | EINECS: | | | Product Categories: | Amino Acids & Derivatives, Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 27244-64-0.mol |  |
| | LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Chemical Properties |
| Melting point | >190°C (dec.) | | Boiling point | 515.2±38.0 °C(Predicted) | | density | 1.606±0.06 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated) | | pka | 2.34±0.25(Predicted) | | form | Solid | | color | Brown to Black | | Stability: | Air Sensitive, Hygroscopic |
| | LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Usage And Synthesis |
| Uses | 6-Hydroxy-L-DOPA is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. | | Uses | 6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. | | Definition | ChEBI: An L-alpha-amino acid that is L-dopa carrying an additional hydroxy substituent at position 6. |
| | LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Preparation Products And Raw materials |
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