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T&W GROUP |
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021-61551611 13296011611 |
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- N3-PEG2-NHS
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-
2026-07-24
- CAS:1312309-64-0
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- Azido-PEG2-NHS Ester
-
-
2026-06-30
- CAS:1312309-64-0
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000kgs
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| | Azido-PEG2-NHS ester Basic information |
| Product Name: | Azido-PEG2-NHS ester | | Synonyms: | Azido-PEG2-CH2CO2-NHS;N3-PEG2-CH2CH2COONHS Ester;N3-PEG2-CH2CO2-NHS;N3-PEG2-C2-NHS ester;2,5-dioxopyrrolidin-1-yl 3-(2-(2-azidoethoxy)ethoxy)propanoate;N3-PEG2-CH2CH2COONHS;N3-PEG2-SPA;Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | | CAS: | 1312309-64-0 | | MF: | C11H16N4O6 | | MW: | 300.27 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1312309-64-0.mol |  |
| | Azido-PEG2-NHS ester Chemical Properties |
| storage temp. | Storage temp. -20°C | | solubility | Soluble in DMSO, DMF, DCM | | form | Liquid | | color | Colorless to light yellow |
| | Azido-PEG2-NHS ester Usage And Synthesis |
| Description | Azido-PEG2-NHS ester is a click chemistry crosslinker containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | | Uses | N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | Non-cleavable Linker |
| | Azido-PEG2-NHS ester Preparation Products And Raw materials |
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