E3 Ligase Ligand-Linker Conjugates 22 manufacturers
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| | E3 Ligase Ligand-Linker Conjugates 22 Basic information |
| Product Name: | E3 Ligase Ligand-Linker Conjugates 22 | | Synonyms: | E3 Ligase Ligand-Linker Conjugates 22;Pomalidomide-PEG4-C2-NH2;Cereblon Ligand-Linker Conjugates 8;1H-Isoindole-1,3(2H)-dione, 4-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-;4-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;inhibit,PomalidomidePEG4C2NH2,E3 Ligase Ligand-Linker Conjugates,Inhibitor,Pomalidomide PEG4 C2 NH2;4-(15-amino-4,7,10,13-tetraoxa-1-azapentadecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione;4-((14-Amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione?, Pomalidomide-PEG4-C2-NH2 | | CAS: | 2225940-52-1 | | MF: | C23H32N4O8 | | MW: | 492.52 | | EINECS: | | | Product Categories: | peg | | Mol File: | 2225940-52-1.mol |  |
| | E3 Ligase Ligand-Linker Conjugates 22 Chemical Properties |
| Boiling point | 714.3±60.0 °C(Predicted) | | density | 1.335±0.06 g/cm3(Predicted) | | pka | 10.74±0.40(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | E3 Ligase Ligand-Linker Conjugates 22 Usage And Synthesis |
| Uses | Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. | | IC 50 | Cereblon | | References | [1] Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1. |
| | E3 Ligase Ligand-Linker Conjugates 22 Preparation Products And Raw materials |
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