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- D-alanine
-
- $70.00
-
2026-09-11
- CAS:338-69-2
- Min. Order: 1kg
- Purity: 0.98
- Supply Ability: 25kg
- D-Alanine
-
-
2026-09-11
- CAS:338-69-2
- Min. Order: 1kg
- Purity: ≥98% HPLC
- Supply Ability: 1000kg
- D-Alanine
-
-
2026-09-11
- CAS:338-69-2
- Min. Order: 1KG
- Purity: 98%min AJI
- Supply Ability: 1000kg
|
| | D-Alanine Basic information |
| | D-Alanine Chemical Properties |
| Melting point | 291 °C (dec.)(lit.) | | alpha | -14.5 º (c=10, 6N HCl) | | Boiling point | 212.9±23.0 °C(Predicted) | | density | 1.4310 (estimate) | | refractive index | -14 ° (C=2, 6mol/L HCl) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | H2O: soluble | | form | Crystalline Powder or Crystals | | pka | 2.31±0.10(Predicted) | | color | White to off-white | | Odor | odorless | | Optical Rotation | Consistent with structure | | Water Solubility | 155 g/L (20 ºC) | | Merck | 14,204 | | BRN | 1720249 | | Major Application | detection
peptide synthesis | | InChI | 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m1/s1 | | InChIKey | QNAYBMKLOCPYGJ-UWTATZPHSA-N | | SMILES | C[C@@H](N)C(O)=O | | LogP | -0.574 (est) | | CAS DataBase Reference | 338-69-2(CAS DataBase Reference) | | NIST Chemistry Reference | D-Alanine(338-69-2) | | EPA Substance Registry System | D-Alanine (338-69-2) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 24/25-36-26 | | WGK Germany | 3 | | TSCA | TSCA listed | | HazardClass | IRRITANT | | HS Code | 29224995 | | Storage Class | 11 - Combustible Solids |
| | D-Alanine Usage And Synthesis |
| Chemical Properties | A white crystalline Powder with no peculiar smell and a sweet taste. It is easily soluble in water, slightly soluble in ethanol, and insoluble in acetone and ether. The decomposition point is 297°C. The specific rotation is [α]25D -1.8° (0.5–2.0 mg/ml, H2O) and [α]25D -14.6° (0.5–2.0 mg/ml, 5 mol/L HCl). | | Uses | D-Alanine is essential for the biosynthesis of peptidoglycan crosslinking sub-units that are used for bacterial cell walls. | | Definition | ChEBI: D-alanine is the D-enantiomer of alanine. It has a role as a human metabolite, an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor and an Escherichia coli metabolite. It is a D-alpha-amino acid and an alanine. It is a conjugate base of a D-alaninium. It is a conjugate acid of a D-alaninate. It is an enantiomer of a L-alanine. It is a tautomer of a D-alanine zwitterion. | | Application | D-Alanine is a LHRH-antagonists, e.g., Abarelix (antineoplas-
tic) | | Preparation | D-Alanine can be obtained by hydrolysis and refining of proteins such as gelatin, sericin and corn protein, or it can be synthesized by chemical methods. | | General Description | Alanine is a non essential amino acid. | | Biochem/physiol Actions | D-Alanine is the non-proteinogenic form of alanine which is used in bacterial cell wall biosynthesis. D-Alanine is used to study the specificity and kinetics of alanine racemase(s) (alaR). | | Purification Methods | Crystallise alanine from H2O or aqueous EtOH, i.e. crystallise it from 25% EtOH in water, or recrystallise it from 62.5% EtOH, wash it with EtOH and dry it to constant weight in vacuo over P2O5. [Gutter & Kegeles J Am Chem Soc 75 3893 1953, Walsh J Biol Chem 264 2394 1989.] 2,2'-Iminodipropionic acid is a likely impurity. [Beilstein 4 IV 2480. 2481.] | | References | [1] ISAO UMEMURA. d-Alanine production from dl-alanine by Candida maltosa with asymmetric degrading activity[J]. Applied Microbiology and Biotechnology, 1992, 36 6: 722-726. DOI:10.1007/BF00172182.
[2] TIAN (AUTUMN) QIU. Biodistribution and racemization of gut-absorbed l/d-alanine in germ-free mice[J]. Communications Biology, 2023: 1-11. DOI:10.1038/s42003-023-05209-y.
[3] AMIT PRIYADARSHI . Structural insights into the alanine racemase from Enterococcus faecalis[J]. Biochimica et biophysica acta. Proteins and proteomics, 2009, 1794 7: Pages 1030-1040. DOI:10.1016/j.bbapap.2009.03.006.
[4] CINDY J. LEE Jonathan V S Tian A Qiu. d-Alanine: Distribution, origin, physiological relevance, and implications in disease[J]. Biochimica et biophysica acta. Proteins and proteomics, 2020, 1868 11: Article 140482. DOI:10.1016/j.bbapap.2020.140482. |
| | D-Alanine Preparation Products And Raw materials |
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