methyl 5-bromo-2-methyl-benzoate
- CAS No.
- 79669-50-4
- Chemical Name:
- methyl 5-bromo-2-methyl-benzoate
- Synonyms
- Methyl 5-bromo-2-methylbenzoate;Methyl 2-Methyl-5-Bromobenzoate;5-bromo-2-methyl-benzoic acid methyl ester;methyl 5-bromo-2-met;Methyl 5-bromo-o-toluate;5-Bromo-o-toluic Acid Methyl Ester;Methyl5-bromo-2-methylbenzoate,98%;Methyl 5-Bromo-2-methylbenzoate >Benzoic acid, 5-bromo-2-methyl-, methyl ester;methyl 5-bromo-2-methyl-benzoate ISO 9001：2015 REACH
- CBNumber:
- CB81456594
- Molecular Formula:
- C9H9BrO2
- Molecular Weight:
- 229.07
- MDL Number:
- MFCD09839555
- MOL File:
- 79669-50-4.mol
- MSDS File:
- SDS
| Melting point | 46.0 to 50.0 °C |
|---|---|
| Boiling point | 265°C(lit.) |
| Density | 1.433±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Powder |
| color | Pale yellow |
| Water Solubility | Soluble in water. |
| InChI | InChI=1S/C9H9BrO2/c1-6-3-4-7(10)5-8(6)9(11)12-2/h3-5H,1-2H3 |
| InChIKey | FDCYLMYCHALQJR-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC(Br)=CC=C1C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2916310090 | |||||||||
| NFPA 704 |
|
methyl 5-bromo-2-methyl-benzoate price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2542 | Methyl 5-Bromo-2-methylbenzoate >98.0%(GC) | 79669-50-4 | 1g | $17 | 2026-04-30 | Buy |
| TCI Chemical | M2542 | Methyl 5-Bromo-2-methylbenzoate >98.0%(GC) | 79669-50-4 | 5g | $66 | 2026-04-30 | Buy |
| ChemScene | CS-W007619 | Methyl 5-bromo-2-methylbenzoate ≥97% | 79669-50-4 | 5g | $9 | 2026-06-04 | Buy |
| ChemScene | CS-W007619 | Methyl 5-bromo-2-methylbenzoate ≥97% | 79669-50-4 | 10g | $11 | 2026-06-04 | Buy |
| ChemScene | CS-W007619 | Methyl 5-bromo-2-methylbenzoate ≥97% | 79669-50-4 | 25g | $17 | 2026-06-04 | Buy |
methyl 5-bromo-2-methyl-benzoate Chemical Properties, Uses, Production
Chemical Properties
Orange-red powder or solid
Uses
Methyl 5-bromo-2-methylbenzoate is used as a catalytic agent, petrochemical additive
Synthesis
67-56-1
79669-49-1
79669-50-4
5-Bromo-2-methylbenzoic acid (1.0 g, 4.7 mmol) was placed in a 200 mL round-bottomed flask under nitrogen protection and methanol was added via syringe. A hexane solution of 2 M diazomethyltrimethylsilane (3.5 mL, 23.0 mmol) was slowly added dropwise over 10 min and the reaction mixture was stirred for 1 h at room temperature. Subsequently, glacial acetic acid (16 mL) was added and stirring was continued for 45 minutes. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (100 mL) and washed sequentially with 1 M aqueous sodium hydroxide solution (30 mL), saturated aqueous sodium bicarbonate solution (30 mL) and brine (30 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give methyl 5-bromo-2-methylbenzoate 1.01 g (99% yield). Methyl 5-bromo-2-methylbenzoate (1.04 g, 4.5 mmol) was placed in a 50 mL round-bottom flask under nitrogen protection and carbon tetrachloride (15 mL) was added. Subsequently, N-bromosuccinimide (1.49 g, 8.3 mmol) and 2,2'-azobisisobutyronitrile (40 mg, 0.2 mmol) were added, a condenser was mounted, and the reaction was refluxed for 4 hours. After completion of the reaction, it was cooled to room temperature and filtered. The filtrate was concentrated under reduced pressure and the crude product was pre-adsorbed through silica gel. The residue was purified by silica gel column chromatography using a gradient elution with a hexane solution of dichloromethane (0 to 50%) to afford methyl 5-bromo-2-bromomethylbenzoate 977 mg (70% yield). Methyl 5-bromo-2-bromomethylbenzoate (0.984 g, 3.20 mmol) and the method described in Part I were used to replace the synthetic step of 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydroisoindol-1-one, which was prepared to give 509 mg of methyl 2-methyl-5-bromobenzoate (75% yield).
References
[1] Patent: WO2005/73205, 2005, A1. Location in patent: Page/Page column 27-28
[2] Patent: WO2014/76104, 2014, A1. Location in patent: Page/Page column 62-63
[3] Patent: CN107474006, 2017, A. Location in patent: Paragraph 0050-0052; 0056-0058; 0062-0064; 0068-0073
[4] Patent: WO2011/80718, 2011, A1. Location in patent: Example 2
[5] Patent: WO2017/46318, 2017, A1. Location in patent: Page/Page column 47
methyl 5-bromo-2-methyl-benzoate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai XinKai Chemical Technology Co., Ltd. | 021-58930698 15921516558 | zhangyichao84@126.com | China | 984 | 55 |
| Dalian lichuang Chemical Co., Ltd | 0411-0411-00000000 13644282108 | 3500508746@qq.com | China | 2942 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from methyl 5-bromo-2-methyl-benzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | methyl 5-bromo-2-methyl-benzoate
79669-50-4
|
1KG | 98%min | 500KGS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2020-01-01 | methyl 5-bromo-2-methyl-benzoate
79669-50-4
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- methyl 5-bromo-2-methyl-benzoate
79669-50-4
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- methyl 5-bromo-2-methyl-benzoate
79669-50-4
- $1.00
- 99%
- Career Henan Chemical Co
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