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| | 2,4-Difluorobenzaldehyde Basic information |
| Product Name: | 2,4-Difluorobenzaldehyde | | Synonyms: | 2,4-Difluorobenzaldehyde, 98% 5GR;Of 2,4-difluorobenzaldehyde;2,4-DIFLUOROBENZALDEHYDE;Benzaldehyde, 2,4-difluoro-;2-fluro-5- nitro-Benzoic acid;2,4-Difluorobenzaldehyde 98%;2,4-Difluorobenzaldehyde98%;2,4-Difluorobenzalde | | CAS: | 1550-35-2 | | MF: | C7H4F2O | | MW: | 142.1 | | EINECS: | 216-287-2 | | Product Categories: | Benzaldehyde;Fluorobenzene;Fluorobenzaldehyde Series;Aldehydes;C7;Carbonyl Compounds;Benzaldehyde series;Fluorine series;Fluorin-contained benzaldehyde series;Aromatic Aldehydes & Derivatives (substituted);john's;intermediate | | Mol File: | 1550-35-2.mol |  |
| | 2,4-Difluorobenzaldehyde Chemical Properties |
| Melting point | 2-3 °C (lit.) | | Boiling point | 65-66 °C/17 mmHg (lit.) | | density | 1.299 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.498(lit.) | | Fp | 131 °F | | storage temp. | Inert atmosphere,2-8°C | | form | Liquid | | Specific Gravity | 1.299 | | color | Clear colorless | | Sensitive | Air Sensitive | | BRN | 2243422 | | InChI | InChI=1S/C7H4F2O/c8-6-2-1-5(4-10)7(9)3-6/h1-4H | | InChIKey | WCGPCBACLBHDCI-UHFFFAOYSA-N | | SMILES | C(=O)C1=CC=C(F)C=C1F | | CAS DataBase Reference | 1550-35-2(CAS DataBase Reference) | | NIST Chemistry Reference | 2,4-Difluorobenzaldehyde(1550-35-2) |
| Hazard Codes | Xi | | Risk Statements | 10-36/37/38 | | Safety Statements | 26-36-37/39-16-36/37 | | RIDADR | UN 1989 3/PG 3 | | WGK Germany | 3 | | F | 10-23 | | Hazard Note | Irritant | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29130000 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| | 2,4-Difluorobenzaldehyde Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | 2,4-Difluorobenzaldehyde was used in the synthesis of 3-benzylidene 20,29-dihydrobetulinic acid derivatives. | | General Description | The emission and absorption spectra of 2,4-difluorobenzaldehyde were studied. | | Synthesis | (1) Device: Refer to Figure 2 to configure the tubular reactor system. The reactor adopts (3a + 3b) type DC channel and round cake pulse diameter adjustable rectangular flat tube combination design, the specific tube diameter and volume need to be calculated according to the reactant flow and the required residence time to determine, the heat transfer medium selection of heat transfer oil. (2) Preparation of catalyst solution: dissolve 6.06 g of cobalt acetate and 6.06 g of sodium molybdate in 200 mL of 2,4-difluorotoluene and 200 mL of acetic acid, respectively, and mix them well to ensure that n (cobalt acetate): n (2,4-difluorotoluene) = 0.015: 1. Preparation of oxidizer solution: dissolve 6.06 g of sodium bromide in 30% H2O2 to form a solution of H2O2-acetic acid. . Subsequently, 2,4-difluorotoluene-acetic acid solution and H2O2-acetic acid solution were injected into a tubular reactor via a constant flow pump at a flow rate of 5.33 mL/min and 10.67 mL/min, respectively, controlling n(H2O2): n(2,4-difluorotoluene) = 2: 1. The reaction was carried out in a microchannel reactor (shown in Fig. 2) at a temperature maintained at 105 °C and a residence time of 400 s. After completion of the reaction, the outlet material was cooled to 0 °C and quenched with dichloromethane. The conversion of 2,4-difluorotoluene was 49.5% and the yield of 2,4-difluorobenzaldehyde was 31.1% by GC analysis. | | References | [1] Patent: CN106588600, 2017, A. Location in patent: Paragraph 0040-0066
[2] Kogyo Kagaku Zasshi, 1956, vol. 59, p. 1160
[3] Chem.Abstr., 1958, p. 13265
[4] Monatshefte fuer Chemie, 1959, vol. 90, p. 683,687
[5] Patent: US5998477, 1999, A |
| | 2,4-Difluorobenzaldehyde Preparation Products And Raw materials |
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