- 2,2-Difluoroethanol
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- $10.00
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2026-05-28
- CAS:359-13-7
- Min. Order: 1KG
- Purity: 99.%
- Supply Ability: 10 ton
- 2,2-Difluoroethanol
-
- $10.00
-
2026-03-20
- CAS:359-13-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10 mt
- 2,2-Difluoroethanol
-
-
2025-08-20
- CAS:359-13-7
- Min. Order: 1kg
- Purity: 99.99%
- Supply Ability: 20 tons
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| | 2,2-Difluoroethanol Basic information |
| Product Name: | 2,2-Difluoroethanol | | Synonyms: | CHF2CH2OH;Ethanol, 2,2-difluoro-;2,2-Difluoroethanol,95%;2,2-Difluoroethanol 97%;2,2-Difluoroethanol97%;2,3-Difluoroethanol;1,1-Difluoro-2-hydroxyethane;2,2-Difluoroethan-1-ol 97% | | CAS: | 359-13-7 | | MF: | C2H4F2O | | MW: | 82.05 | | EINECS: | 670-547-3 | | Product Categories: | Four-membered heterocyclic compound;bc0001 | | Mol File: | 359-13-7.mol |  |
| | 2,2-Difluoroethanol Chemical Properties |
| Melting point | -28°C | | Boiling point | 95 °C | | density | 1.296 | | refractive index | 1.338 | | Fp | 3°C | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | soluble in chloroform, ethanol. | | pka | 13.00±0.10(Predicted) | | form | clear liquid | | color | Colorless to Almost colorless | | Specific Gravity | 1.296 | | BRN | 1731617 | | Henry's Law Constant | 9.3×10-1 mol/(m3Pa) at 25℃, Burkholder et al. (2019) | | CAS DataBase Reference | 359-13-7(CAS DataBase Reference) | | NIST Chemistry Reference | Difluoroethanol(359-13-7) | | EPA Substance Registry System | 2,2-Difluoroethanol (359-13-7) |
| | 2,2-Difluoroethanol Usage And Synthesis |
| Chemical Properties | Colorless Liquid | | Uses | 2,2-Difluoroethanol is used as a chemical intermediates. It has wide applications in medicine and fluoropolymers. | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 23, p. 985, 1980 DOI: 10.1021/jm00183a005 | | Synthesis | Example 13: Synthesis of 2,2-difluoroethanol from ethyl 2,2-difluoroacetate (Step b2)
In a 0.5 L glass reactor equipped with a mechanical stirrer, reflux condenser and temperature probe, 164 g of ethyl 2,2-difluoroacetate (GC purity 95%), 106 g of methanol, and 3 g of solid NaOH were added. the reaction was carried out at 65 °C for 2 h until the conversion was complete. The 2,2-difluoroethanol was isolated by distillation to give 96.3% GC purity and 87% isolated yield. | | References | [1] Patent: CN107986944, 2018, A. Location in patent: Paragraph 0020; 0023; 0026; 0029; 0032
[2] Patent: WO2009/40367, 2009, A1. Location in patent: Page/Page column 12
[3] Patent: US2014/243561, 2014, A1. Location in patent: Paragraph 0040; 0041; 0042
[4] Patent: WO2009/40367, 2009, A1. Location in patent: Page/Page column 10
[5] Patent: CN108178723, 2018, A. Location in patent: Paragraph 0015; 0016; 0018; 0020 |
| | 2,2-Difluoroethanol Preparation Products And Raw materials |
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