ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Valine derivatives >H-Nva-OMe HCl

H-Nva-OMe HCl

H-Nva-OMe HCl Suppliers list
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel: 4006356688 18621169109
Email: market03@meryer.com
Company Name: Energy Chemical  
Tel: 400-0056266
Email: sales8178@energy-chemical.com
Company Name: Capot Chemical Co., Ltd  
Tel: +86 (0) 571 85 58 67 18
Email:
Company Name: Jia Xing Isenchem Co.,Ltd  
Tel: 0573-85285100 18627885956
Email: isenchem@163.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Email: info@hanhongsci.com

H-Nva-OMe HCl manufacturers

  • H-NVA-OME HCL
  • H-NVA-OME HCL pictures
  • $100.00
  • 2019-07-06
  • CAS:56558-30-6
  • Min. Order: 1KG
  • Purity: 99%
H-Nva-OMe HCl Basic information
Product Name:H-Nva-OMe HCl
Synonyms:NORVALINE-OME HCL;L-2-AMINOVALERIC ACID-METHYL ESTER HCL;L-NORVALINE METHYL ESTER HCL;L-NORVALINE METHYL ESTER HYDROCHLORIDE;(S)-methyl 2-aminopentanoate hydrochloride;H-Nva-OMe hydrochloride;Methyl norvalinate hydrochloride;Methyl L-norvalinate hydrochloride
CAS:56558-30-6
MF:C6H13NO2.ClH
MW:167.63
EINECS:1533716-785-6
Product Categories:
Mol File:56558-30-6.mol
H-Nva-OMe HCl Structure
H-Nva-OMe HCl Chemical Properties
Melting point 103-105 °C
storage temp. Inert atmosphere,Room Temperature
form Solid
color Off-white to white
Safety Information
HazardClass IRRITANT
HS Code 2922498590
MSDS Information
H-Nva-OMe HCl Usage And Synthesis
Chemical PropertiesWhite to off-white powder
Uses(S)-Methyl 2-Aminopentanoate Hydrochloride can be prepared to use as a pesticides.
Synthesis
Methanol

67-56-1

L-Norvaline

6600-40-4

H-NVA-OME HCL

56558-30-6

L-norvaline (160 g, 1.34 mol) was dissolved in 28.5% hydrochloric acid solution (278 g) and diluted with methanol (500 ml). The reaction mixture was refluxed for 6 hours under the protection of inert atmosphere. After completion of the reaction, the solvent was removed by co-evaporation with toluene. The residue was treated with tert-butyl methyl ether (800 ml) at 50 °C. The resulting suspension was stirred at room temperature and subsequently filtered. The resulting white solid was washed with tert-butyl methyl ether to give 216 g of L-norvaline methyl ester hydrochloride in 97% yield.

References[1] Angewandte Chemie, 1992, vol. 104, # 1, p. 97 - 99
[2] Synthesis, 2010, # 17, p. 2915 - 2921
[3] Patent: WO2013/136265, 2013, A1. Location in patent: Page/Page column 21-22
[4] Patent: WO2004/33434, 2004, A1. Location in patent: Page 34
[5] Heterocycles, 1998, vol. 47, # 2, p. 765 - 780
H-Nva-OMe HCl Preparation Products And Raw materials
Raw materialsMethanol-->L-Norvaline
Tag:H-Nva-OMe HCl(56558-30-6) Related Product Information
L-Norvaline tert-butyl ester hydrochloride L-Norvaline ethyl ester hydrochloride Methyl L-leucinate hydrochloride Ethyl L-leucinate hydrochloride L-Leucine tert-butyl ester hydrochloride Ethyl N-benzoyl-L-argininate hydrochloride L-Glutamic acid dimethyl ester hydrochloride Diethyl L-glutamate hydrochloride Methyl L-argininate dihydrochloride Methyl L-prolinate hydrochloride H-Lys(Z)-OMe HCl Ac-Lys-OMe HCl L-Norvaline Ne-Boc-L-lysine tert-butyl ester hydrochloride Methyl L-isoleucinate hydrochloride Tos-Arg-OMe HCl H-Glu(OBzl)-OBzl HCl H-Lys(Z)-OtBu.HCl