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2-Chloro-5-hydroxypyridine

2-Chloro-5-hydroxypyridine Structure
2-Chloro-5-hydroxypyridine structure
CAS No.
41288-96-4
Chemical Name:
2-Chloro-5-hydroxypyridine
Synonyms
6-CHLOROPYRIDIN-3-OL;2-Chloro-5-Pyridol;2-CHLORO-5-PYRIDINOL;6-Chloro-3-pyridinol;2-Chloropyridin-5-ol;6-chloropyridine-3-ol;3-PYRIDINOL, 6-CHLORO-;2-Chloro-5-hydropyridine;2-CHLORO-5-HYDROXYPYRIDINE;3-Pyridinol,6-chloro-(9CI)
CBNumber:
CB8695961
Molecular Formula:
C5H4ClNO
Molecular Weight:
129.54
MDL Number:
MFCD00234050
MOL File:
41288-96-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:07:40
Product description Number Pack Size Price
2-Chloro-5-hydroxypyridine >97.0%(GC)(T) C2271 5g $140
2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) 230166 1g $159
2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) 230166 5g $206
2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) 230166 25g $375
2-Chloro-5-hydroxypyridine FC00525 0.1kg $150
More product size
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2-Chloro-5-hydroxypyridine Properties

Melting point 155-158°C
Boiling point 351.9±22.0 °C(Predicted)
Density 1.392±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form powder to crystal
pka 8.69±0.10(Predicted)
color Light yellow to Brown
InChI InChI=1S/C5H4ClNO/c6-5-2-1-4(8)3-7-5/h1-3,8H
InChIKey KVCOOWROABTXDJ-UHFFFAOYSA-N
SMILES C1=NC(Cl)=CC=C1O
CAS DataBase Reference 41288-96-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  T,Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36/37/39-36-37
HazardClass  IRRITANT
PackingGroup  III
HS Code  29333990
NFPA 704
1
2 0

2-Chloro-5-hydroxypyridine price More Price(89)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2271 2-Chloro-5-hydroxypyridine >97.0%(GC)(T) 41288-96-4 5g $140 2026-04-30 Buy
Usbiological 230166 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) 1g $159 2026-06-03 Buy
Usbiological 230166 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) 5g $206 2026-06-03 Buy
Usbiological 230166 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) 25g $375 2026-06-03 Buy
Biosynth FC00525 2-Chloro-5-hydroxypyridine 41288-96-4 0.1kg $150 2026-06-04 Buy
Product number Packaging Price Buy
C2271 5g $140 Buy
230166 1g $159 Buy
230166 5g $206 Buy
230166 25g $375 Buy
FC00525 0.1kg $150 Buy

2-Chloro-5-hydroxypyridine Chemical Properties,Uses,Production

Uses

2-Chloro-5-hydroxypyridine is an organic intermediate.

Chemical Properties

Light yellow Cryst

Synthesis

6-CHLORO-3-PYRIDINYL ACETATE

188057-24-1

2-Chloro-5-hydroxypyridine

41288-96-4

11B. 6-Chloropyridin-3-yl acetate (11.1 g, 64.7 mmol) from step 11a was dissolved in methanol at room temperature, followed by addition of solid potassium carbonate (4.47 g, 32.4 mmol). The reaction mixture was stirred for 2 hours and the volatiles were removed under reduced pressure. The residue was diluted with ether and water, and the aqueous phase was neutralized to pH 7 by addition of aqueous 1 N hydrochloric acid.The organic and aqueous layers were separated and the aqueous phase was extracted twice with ether. The organic extracts were combined, dried over magnesium sulfate and concentrated to give 2-chloro-5-hydroxypyridine as a white solid (8.03 g, 96% yield): melting point 155 °C; 1H NMR (CD3OD, 300 MHz) δ 7.20-7.28 (m, 2H), 7.88 (m, 1H); mass spectrum (CI/NH3) m/z: 130,132 (M+H) +; 147,149 (M+NH4)+.

References

[1] Patent: US6696439, 2004, B1. Location in patent: Page column 20
[2] Patent: US6001849, 1999, A
[3] Tetrahedron Letters, 2003, vol. 44, # 4, p. 725 - 728
[4] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 24
[5] Patent: WO2004/72072, 2004, A1. Location in patent: Page 85

2-Chloro-5-hydroxypyridine synthesis

188057-24-1
41288-96-4
Synthesis of 2-Chloro-5-hydroxypyridine from 6-CHLORO-3-PYRIDINYL ACETATE

2-Chloro-5-hydroxypyridine Preparation Products And Raw materials

Raw materials

Benzene, 1-[(1,1-dimethylethyl)sulfinyl]-4-methyl-, (R)- Ethyl 2-(6-chloropyridin-3-yloxy)-2-methylpropanoate Potassium 6-chloropyridine-3-trifluoroborate 6-CHLORO-3-PYRIDINYL ACETATE 2-CHLORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
2-Chloro-5-iodopyridine 2-Chloro-3-hydroxypyridine 5-Amino-2-chloropyridine Methanol Hydrochloric acid

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Preparation Products

6-Chloro-3-hydroxy-2-nitropyridine 6-CHLORO-2-IODO-3-HYDROXYPYRIDINE tert-Butyl 4-{[(6-chloropyridin-3-yl)oxy]methyl}piperidine-1-carboxylate 3-Pyridinol, 6-(4-morpholinyl)- PYRIDINE, 2-CHLORO-5-(PHENYLMETHOXY)-

2-Chloro-5-hydroxypyridine Suppliers

Global( 418)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+86-15350571055 Sibel@chuanghaibio.com China 8737 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106 sales@frappschem.com China 877 50
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21531 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32998 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2993 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10399 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8491 58
Accela ChemBio Inc. 		+1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Frapp's ChemicalNFTZ Co., Ltd. 		50
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Accela ChemBio Inc. 		58

View Lastest Price from 2-Chloro-5-hydroxypyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-hydroxypyridine pictures 2026-03-20 2-Chloro-5-hydroxypyridine
41288-96-4
 $8.90 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Chloro-5-hydroxypyridine pictures 2025-11-18 2-Chloro-5-hydroxypyridine
41288-96-4
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-Chloro-5-hydroxypyridine pictures 2025-04-04 2-Chloro-5-hydroxypyridine
41288-96-4
 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

2-Chloro-5-hydroxypyridine Spectrum

2-Chloro-5-hydroxypyridine(41288-96-4)1HNMR2-Chloro-5-hydroxypyridine(41288-96-4)FT-IR

41288-96-4(2-Chloro-5-hydroxypyridine)Related Search:

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Chromium picolinate 2-Chloro-3-cyanopyridine Pentachloropyridine Chrysin 5-Amino-2-chloropyridine
2-chloro-5-cyanopyridine 3-Bromo-6-chloro-2-methylpyridine 5-Bromo-2-chloropyridine 6-Chloro-2-methyl-3-nitropyridine 2-CHLORO-5-METHOXYPYRIDINE
2-Chloro-5-nitropyridine 2-Chloro-5-iodopyridine 5-Bromo-2-chlorobenzoic acid

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6-Chloro-3-pyridinol 3-PYRIDINOL, 6-CHLORO- 2-CHLORO-5-HYDROXYPYRIDINE 2-CHLORO-5-PYRIDINOL 2-Chloro-5-Pyridol 2-Chloropyridin-5-ol 3-Pyridinol,6-chloro-(9CI) 2-CHLORO-5-HYDROXYPYRIDINE 98% 2-CHLORO-5-HYDROXYPYRIDINE 99+% 2-Chloro-5-hydropyridine 6-chloropyridine-3-ol 2-Chloro-5-hydroxypyridine 98+% 2-Chloropyridin-5-ol, 6-Chloropyridin-3-ol 2-Chloro-5-hydroxypyridine≥ 99% (HPLC) 2-Chloro-5-hydroxypyridine(RS20004430) 2-Chloro-5-hydroxypyridine> 2-Chloro-5-hydroxypyridine ISO 9001：2015 REACH 6-CHLOROPYRIDIN-3-OL 41288-96-4 17368-12-7 Building Blocks Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Boronic Acid Halides Pyridines Pyridines derivates PYRIDINE pyridine derivative Pyridine Series