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Fmoc-11-aminoundecanoic acid

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Company Name: BeiJing Hwrk Chemicals Limted  
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Fmoc-11-aminoundecanoic acid manufacturers

Fmoc-11-aminoundecanoic acid Basic information
Product Name:Fmoc-11-aminoundecanoic acid
Synonyms:NALPHA-9-Fluorenylmethoxycarbonyl-11-aminoundecanoic acid;FMOC-11-AMINOUNDECYLIC ACID;FMOC-11-AUN-OH;FMOC-NH-(CH2)10-COOH;11-(FMOC-AMINO)UNDECANOIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-11-AMINOUNDECANOIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-11-AMINOUNDECYLIC ACID;N-(9-FLUORENYLMETHYLOXYCARBONYL)-11-AMINO-UNDECANOIC ACID
CAS:88574-07-6
MF:C26H33NO4
MW:423.54
EINECS:
Product Categories:Amino Acids
Mol File:88574-07-6.mol
Fmoc-11-aminoundecanoic acid Structure
Fmoc-11-aminoundecanoic acid Chemical Properties
storage temp. 2-8°C
form powder
color white
BRN 4887890
Major Applicationpeptide synthesis
InChI1S/C26H33NO4/c28-25(29)17-7-5-3-1-2-4-6-12-18-27-26(30)31-19-24-22-15-10-8-13-20(22)21-14-9-11-16-23(21)24/h8-11,13-16,24H,1-7,12,17-19H2,(H,27,30)(H,28,29)
InChIKeyIMEVDILDSCXKJW-UHFFFAOYSA-N
SMILESOC(=O)CCCCCCCCCCNC(=O)OCC1c2ccccc2-c3ccccc13
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 2924297099
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
SigmaAldrich English
Fmoc-11-aminoundecanoic acid Usage And Synthesis
DescriptionFmoc-11-aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Fmoc-11-aminoundecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
UsesFmoc-11-aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-11-aminoundecanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
reaction suitabilityreaction type: Fmoc solid-phase peptide synthesis
Fmoc-11-aminoundecanoic acid Preparation Products And Raw materials
Tag:Fmoc-11-aminoundecanoic acid(88574-07-6) Related Product Information
Fmoc-Abu-OH Fmoc-gamma-Abu-OH Fmoc-D-allo-Ile-OH N-FMoc-L-norvaline Fmoc-L-Glutamic acid 1-tert-butyl ester Fmoc-L-phenylglycine (2R,3S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-hydroxybutanoic acid hydrate Fmoc-L-Serine FMoc-D-serine Methyl ester Fmoc-Aib-OH Fmoc-D-leucine Fmoc-D-Ser-OH Fmoc-D-beta-homoalanine Fmoc-D-Tyr-OH Fmoc-D-Phg-OH Fmoc-Ser-OMe Fmoc-D-hocha-OH Fmoc-hocha-OH